scholarly journals Template-promoted self-replication in dynamic combinatorial libraries made from a simple building block

2018 ◽  
Vol 54 (93) ◽  
pp. 13096-13098 ◽  
Author(s):  
B. Bartolec ◽  
M. Altay ◽  
S. Otto
Keyword(s):  
Self Assembly ◽  
Building Block ◽  
Combinatorial Libraries ◽  
Self Replication ◽  
Simple Building Block

Self-assembly driven self-replication based on a very simple building block is facilitated by a template.

Building understanding: Sensitive issues and putting the researcher in the research

2010 ◽  
Vol 12 (1) ◽  
Author(s):  
Jennifer O'Brien
Keyword(s):  
Building Block ◽  
Ethical Dilemmas ◽  
Ethical Consideration ◽  
Ethnographic Research ◽  
Research Groups ◽  
Methodological Consideration ◽  
Sensitive Issues ◽  
Simple Building Block

Stemming from ethnographic research in a chronically poor district of rural Uganda, this paper recounts a number of attempts to investigate young people’s understanding of HIV and its transmission. The failure of the initial, more traditional methodologies are used to critically evaluate the positionality or role the researcher played as she became embedded within the community to the extent she lost objectivity as a researcher. Inadvertently, a simple building block game was used as a methodology. This was successful in generating interesting ‘data’ and proved that even research groups deemed difficult to access can be reached with some methodological consideration. The tool was, however, almost over successful and generated dramatic ethical dilemmas which ethically questioned the potential of the research and had a significant impact on the researcher. This paper therefore stresses the necessity to give ethical consideration to the research and its participants but to not over look the researcher.

scholarly journals Self-replication of a quantum artificial organism driven by single-photon pulses

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Daniel Valente
Keyword(s):  
Self Assembly ◽  
Artificial Life ◽  
Single Photon ◽  
Self Organization ◽  
Physical Systems ◽  
Self Organized ◽  
Living Organisms ◽  
A Chain ◽  
Thermodynamic Mechanism ◽  
Self Replication

AbstractImitating the transition from inanimate to living matter is a longstanding challenge. Artificial life has achieved computer programs that self-replicate, mutate, compete and evolve, but lacks self-organized hardwares akin to the self-assembly of the first living cells. Nonequilibrium thermodynamics has achieved lifelike self-organization in diverse physical systems, but has not yet met the open-ended evolution of living organisms. Here, I look for the emergence of an artificial-life code in a nonequilibrium physical system undergoing self-organization. I devise a toy model where the onset of self-replication of a quantum artificial organism (a chain of lambda systems) is owing to single-photon pulses added to a zero-temperature environment. I find that spontaneous mutations during self-replication are unavoidable in this model, due to rare but finite absorption of off-resonant photons. I also show that the replication probability is proportional to the absorbed work from the photon, thereby fulfilling a dissipative adaptation (a thermodynamic mechanism underlying lifelike self-organization). These results hint at self-replication as the scenario where dissipative adaptation (pointing towards convergence) coexists with open-ended evolution (pointing towards divergence).

Laterally functionalized pillar[5]arene: a new building block for covalent self-assembly

2017 ◽  
Vol 53 (64) ◽  
pp. 9024-9027 ◽  
Author(s):  
Shuang Fu ◽  
Guo An ◽  
Hongcheng Sun ◽  
Quan Luo ◽  
Chunxi Hou ◽  
...  
Keyword(s):  
Polymer Films ◽  
Self Assembly ◽  
Building Block ◽  
2D Polymer

Polymer nanocapsules and 2D-polymer films were successfully constructed by using a novel laterally functionalized pillararene derivative.

A ‘Building Block’ Approach To Mixed-Colloid Systems Through Electrostatic Self-Organization

2001 ◽  
Vol 676 ◽  
Author(s):  
Trent H. Galow ◽  
Andrew K. Boal ◽  
Vincent M. Rotello
Keyword(s):  
Particle Size ◽  
Self Assembly ◽  
Building Block ◽  
Acid Base ◽  
Electrostatic Assembly ◽  
Polymer Colloid ◽  
Colloid Systems ◽  
Carboxylic Acid Derivative ◽  
Block Approach ◽  
Shape And Size

ABSTRACTWe have developed a highly modular electrostatically-mediated approach to colloid-colloid and polymer-colloid networks using ‘building block’ and ‘bricks and mortar’ self-assembly methodologies, respectively. The former approach involved functionalization of one type of nanoparticle building block with a primary amine and a counterpart building block with a carboxylic acid derivative. After combining these two systems, acid-base chemistry followed by immediate charge-pairing resulted in the spontaneous formation of electrostatically-bound mixed-nanoparticle constructs. The shape and size of these ensembles were controlled via variation of particle size and stoichiometries. In the ‘bricks and mortar’ approach, a functionalized polymer is combined with complementary nanoparticles to provide mixed polymer-nanoparticle networked structures. A notable feature is the inherent porosity resulting from the electrostatic assembly. The shape and size of these ensembles were controlled via variation of particle size, stoichiometries and the order in which they were added.

Self-Assembly of Goldberg Polyhedra from a Concave [WV5O11(RCO2)5(SO4)]3–Building Block with 5-Fold Symmetry

2018 ◽  
Vol 140 (50) ◽  
pp. 17365-17368 ◽  
Author(s):  
Yuteng Zhang ◽  
Hongmei Gan ◽  
Chao Qin ◽  
Xinlong Wang ◽  
Zhongmin Su ◽  
...  
Keyword(s):  
Self Assembly ◽  
Building Block

Halide ion-driven self-assembly of Zn(ii) compounds derived from an asymmetrical hydrazone building block: a combined experimental and theoretical study

2016 ◽  
Vol 40 (12) ◽  
pp. 10116-10126 ◽  
Author(s):  
Ghodrat Mahmoudi ◽  
Farhad Akbari Afkhami ◽  
Himanshu Sekhar Jena ◽  
Parisa Nematollahi ◽  
Mehdi D. Esrafili ◽  
...  
Keyword(s):  
Self Assembly ◽  
Building Block ◽  
Theoretical Study ◽  
Counter Ion ◽  
Non Covalent Interactions ◽  
Covalent Interactions

Self-assembly of Zn(ii) compounds is influenced by a counter ion and non-covalent interactions.

scholarly journals Crystal engineered acid-base complexes with 2d and 3d hydrogen bonding systems using p-hydroxybenzoic acid as the building block

2010 ◽  
Vol 75 (4) ◽  
pp. 459-473 ◽  
Author(s):  
Pu Zhao ◽  
Xian Wang ◽  
Fang Jian ◽  
Jun Zhang ◽  
Lian Xiao
Keyword(s):  
Self Assembly ◽  
Building Block ◽  
Three Dimensional ◽  
Hydroxybenzoic Acid ◽  
Acid Base ◽  
3D Network ◽  
Acid And Base ◽  
Butyl Amine ◽  
Bonding Systems ◽  
Simply Connected

p-Hydroxybenzoic acid (p-HOBA) was selected as the building block for self-assembly with five bases, i.e., diethylamine, tert-butyl amine, cyclohexylamine, imidazole and piperazine, and generate the corresponding acid-base complexes 1-5. Crystal structure analyses suggest that proton-transfer from the carboxyl hydrogen to the nitrogen atom of the bases can be observed in 1-4; while only in 5 does a solvent water molecule co-exists with p-HOBA and piperazine. With the presence of O-H?O hydrogen bonds in 1-4, the deprotonated p-hydroxybenzoate anions (p-HOBAA-) are simply connected each other in a head-to-tail motif to form one-dimensional (1D) arrays, which are further extended to distinct two-dimensional (2D) (for 1 and 4) and three-dimensional (3D) (for 2 and 3 ) networks via N-H?O interactions. While in 5, neutral acid and base are combined pair wise by O-H?N and N-H?O bonds to form a 1D tape and then the 1D tapes are sequentially combined by water molecules to create a 3D network. Some interlayer or intralayer C-H?O, C-H?? and ??? interactions help to stabilize the supramolecular buildings. Melting point determination analyses indicate that the five acidbase complexes are not the ordinary superposition of the reactants and they are more stable than the original reactants.

Oxidation-induced control of self-assembly using a bis-dipyrromethyl substituted phenanthroline building block

2008 ◽  
Vol 32 (5) ◽  
pp. 777
Author(s):  
Patrick Plitt ◽  
Vincent M. Lynch ◽  
Jonathan L. Sessler
Keyword(s):  
Self Assembly ◽  
Building Block

Synthesis of 6-hydroxy-N-(6-methylpyridin-2-yl) naphthalene-2- carboxamide and its alkoxy analogues

2017 ◽  
Vol 1 (3) ◽  
Author(s):  
Braja G. Bag ◽  
Subrata Ghorai ◽  
Saikat K. Panja ◽  
Shaishab K. Dinda ◽  
Koushik Paul
Keyword(s):  
Self Assembly ◽  
Alkyl Chains ◽  
Replication Studies ◽  
Naphthoic Acid ◽  
New Strategy ◽  
Donor Acceptor ◽  
High Yields ◽  
Self Replication

6-hydroxy-N-(6-methylpyridin-2-yl)naphthalene-2- carboxamide and its alkoxy analogues bearing long alkyl chains have been synthesized using 6-hydroxy-2-naphthoic acid and 2-amino-6-picoline. The facile synthetic scheme reported here using conventional laboratory reagents opens up a new strategy for the generation of libraries of such compounds in high yields. The H-bond donor acceptor groups along with the reactive 2-naphthol moiety present in the target compounds make them useful for their use in self-assembly and self-replication studies.

Sign in / Sign up

Export Citation Format

Share Document