One-step detection of hexokinase activity using a personal glucose meter

2018 ◽  
Vol 10 (18) ◽  
pp. 2075-2080 ◽  
Author(s):  
Jie Bai ◽  
Liyan Liu ◽  
Yanmei Han ◽  
Congcong Jia ◽  
Cuixia Liang
Keyword(s):  
Hexokinase Activity ◽  
Step Detection ◽  
Personal Glucose Meter ◽  
One Step ◽  
Glucose Meter

Using commercially available personal glucose meters for the determination of hexokinase activity.

A sensitive one-step method for quantitative detection of α-amylase in serum and urine using a personal glucose meter

The Analyst ◽  
2015 ◽  
Vol 140 (4) ◽  
pp. 1161-1165 ◽  
Author(s):  
Qing Wang ◽  
Hui Wang ◽  
Xiaohai Yang ◽  
Kemin Wang ◽  
Rongjuan Liu ◽  
...  
Keyword(s):  
Amylase Activity ◽  
Direct Determination ◽  
Quantitative Detection ◽  
Step Method ◽  
Personal Glucose Meter ◽  
One Step ◽  
Glucose Meter ◽  
Serum And Urine

A one-step assay for direct determination of α-amylase activity in serum and urine was developed using a portable personal glucose meter.

A portable and antibody-free sandwich assay for determination of chloramphenicol in food based on a personal glucose meter

2015 ◽  
Vol 407 (9) ◽  
pp. 2499-2507 ◽  
Author(s):  
Si Chen ◽  
Ning Gan ◽  
Huairong Zhang ◽  
Futao Hu ◽  
Tianhua Li ◽  
...  
Keyword(s):  
Sandwich Assay ◽  
Personal Glucose Meter ◽  
Glucose Meter

Development and Validation of an LC-MS/MS Method for Simultaneous Determination of Canagliflozin and Metformin HCl in Rat Plasma and its Application

2020 ◽  
Vol 16 (6) ◽  
pp. 752-762
Author(s):  
Vivek Nalawade ◽  
Vaibhav A. Dixit ◽  
Amisha Vora ◽  
Himashu Zade
Keyword(s):  
Internal Standard ◽  
Rat Plasma ◽  
Precipitation Method ◽  
Herbal Extracts ◽  
One Step ◽  
Precision And Accuracy ◽  
Development And Validation ◽  
The Impact ◽  
Metformin Hcl

Background: Food and herbal extracts rich in Quercetin (QRT) are often self-medicated by diabetics and can potentially alter the pharmacokinetics (PK) of Metformin HCl (MET) and Canagliflozin (CNG) leading to food or herb-drug interactions and reduced therapeutic efficacy. However, the impact of these flavonoids on the pharmacokinetic behaviour of MET and CNG is mostly unknown. Methods: A simple one-step protein precipitation method was developed for the determination of MET and CNG from rat plasma. The mobile phase chosen was MeOH 65% and 35% water containing 0.1% formic acid at a flow rate of 1mL/min. Results: The retention time of MET, internal standard (Valsartan) and CNG was 1.83, 6.2 and 8.2 min, respectively. The method was found to be linear in the range of 200 - 8000 ng/mL for CNG and 100 = 4000 ng/ml for MET. Precision and accuracy of the method were below 20% at LLOQ and below 15% for LQC, MQC, and HQC. Conclusion: The method was successfully applied for the determination of PK of MET and CNG by using 100 μL of rat plasma. QRT co-administration affects the PK parameters of MET and CNG. This alteration in PK parameters might be of significant use for clinicians and patients.

scholarly journals Chlorine-Functional Silsesquioxanes (POSS-Cl) as Effective Flame Retardants and Reinforcing Additives for Rigid Polyurethane Foams

Molecules ◽  
2021 ◽  
Vol 26 (13) ◽  
pp. 3979
Author(s):  
Anna Strąkowska ◽  
Sylwia Członka ◽  
Karolina Miedzińska ◽  
Krzysztof Strzelec
Keyword(s):  
Flame Retardants ◽  
Elevated Temperatures ◽  
Bending Strength ◽  
Reaction System ◽  
Fire Retardant ◽  
Polyurethane Foams ◽  
Polymerization Reaction ◽  
Three Point Bending ◽  
One Step

The subject of the research was the production of silsesquioxane modified rigid polyurethane (PUR) foams (POSS-Cl) with chlorine functional groups (chlorobenzyl, chloropropyl, chlorobenzylethyl) characterized by reduced flammability. The foams were prepared in a one-step additive polymerization reaction of isocyanates with polyols, and the POSS modifier was added to the reaction system in an amount of 2 wt.% polyol. The influence of POSS was analyzed by performing a series of tests, such as determination of the kinetics of foam growth, determination of apparent density, and structure analysis. Compressive strength, three-point bending strength, hardness, and shape stability at reduced and elevated temperatures were tested, and the hydrophobicity of the surface was determined. The most important measurement was the determination of the thermal stability (TGA) and the flammability of the modified systems using a cone calorimeter. The obtained results, after comparing with the results for unmodified foam, showed a large influence of POSS modifiers on the functional properties, especially thermal and fire-retardant, of the obtained PUR-POSS-Cl systems.

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