A dual signal amplification method for exosome detection based on DNA dendrimer self-assembly

The Analyst ◽  
2019 ◽  
Vol 144 (6) ◽  
pp. 1995-2002 ◽  
Author(s):  
Mei-Ling Gao ◽  
Fang He ◽  
Bin-Cheng Yin ◽  
Bang-Ce Ye
Keyword(s):  
Self Assembly ◽  
Signal Amplification ◽  
Vital Role ◽  
Amplification Method ◽  
Dual Signal Amplification

An increasing number of studies have found that circulating exosomes play a vital role in the occurrence and metastasis of cancer.

Hairpin DNA-fueled dynamic self-assembly of three-arm DNA branched junctions consisting of active DNAzyme structures for enzyme-free ultrasensitive detection of nucleic acids

2016 ◽  
Vol 8 (47) ◽  
pp. 8262-8265 ◽  
Author(s):  
Ke Yang ◽  
Ming Zeng ◽  
Xing He ◽  
Jianming Li ◽  
Dinggeng He
Keyword(s):  
Nucleic Acids ◽  
Self Assembly ◽  
Signal Amplification ◽  
Ultrasensitive Detection ◽  
Hairpin Dna ◽  
Amplification Strategy ◽  
Dual Signal Amplification

An enzyme-free dual signal amplification strategy based on programmable molecular hairpins has been developed for amplified detection of DNA via the hairpin DNA-fueled dynamic self-assembly of three-arm DNAzyme.

A dual signal amplification method for miR-204 assay by combining chimeric molecular beacon with double-stranded nuclease

2018 ◽  
Vol 10 (48) ◽  
pp. 5834-5841 ◽  
Author(s):  
Hao Liu ◽  
Jialong Fan ◽  
Weiping Liu ◽  
Chunyi Tong ◽  
Zhenhua Xie ◽  
...  
Keyword(s):  
Signal Amplification ◽  
Molecular Beacon ◽  
Disease Diagnosis ◽  
Early Disease ◽  
Amplification Method ◽  
Dual Signal Amplification

Due to the miRNA's key roles in early disease diagnosis, an assay based on chimeric molecular beacon was constructed for miR204 detection with LOD lower to 50 pM.

A dual-signal amplification method for the DNA detection based on exonuclease III

2014 ◽  
Vol 61 ◽  
pp. 370-373 ◽  
Author(s):  
Zhimin Cai ◽  
Yiying Chen ◽  
Chunshui Lin ◽  
Yanfang Wu ◽  
Chaoyong James Yang ◽  
...  
Keyword(s):  
Signal Amplification ◽  
Dna Detection ◽  
Exonuclease Iii ◽  
Amplification Method ◽  
Dual Signal Amplification

A sensitive dual signal amplification method for western blotting based on antibody-functionalised graphene oxide and gold nanoparticles

The Analyst ◽  
2012 ◽  
Vol 137 (16) ◽  
pp. 3620 ◽  
Author(s):  
Hongjun Lin ◽  
Jingrui Huo ◽  
Aihong Zhang ◽  
Yingfu Liu ◽  
Qingming Wang ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Graphene Oxide ◽  
Western Blotting ◽  
Signal Amplification ◽  
Amplification Method ◽  
Dual Signal Amplification
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