Label-free determination of adenosine and mercury ions according to force mapping-based force-to-color variety

The Analyst ◽  
2018 ◽  
Vol 143 (18) ◽  
pp. 4400-4407 ◽  
Author(s):  
Qing Li ◽  
Gang Wei
Keyword(s):  
Label Free ◽  
Mercury Ions ◽  
Label Free Detection ◽  
Force Mapping

Force mapping can be used as a novel force-to-color sensing technique for the label-free detection of adenosine and Hg2+.

Biogenic Quantum Dots for Sensitive, Label-Free Detection of Mercury Ions

2019 ◽  
Vol 2 (6) ◽  
pp. 2661-2667 ◽  
Author(s):  
Li-Jiao Tian ◽  
Yuan Min ◽  
Xue-Meng Wang ◽  
Jie-Jie Chen ◽  
Wen-Wei Li ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Label Free ◽  
Mercury Ions ◽  
Label Free Detection

scholarly journals Direct and Competitive Optical Grating Immunosensors for Determination of Fusarium Mycotoxin Zearalenone

Toxins ◽  
2021 ◽  
Vol 13 (1) ◽  
pp. 43
Author(s):  
Inna Székács ◽  
Nóra Adányi ◽  
István Szendrő ◽  
András Székács
Keyword(s):  
Environmental Safety ◽  
Detection Methods ◽  
Label Free ◽  
Detection Range ◽  
Fusarium Mycotoxin ◽  
Label Free Detection ◽  
Optical Grating ◽  
Covalent Immobilisation ◽  
Magnitude Improvement

Novel optical waveguide lightmode spectroscopy (OWLS)-based immunosensor formats were developed for label-free detection of Fusarium mycotoxin zearalenone (ZON). To achieve low limits of detection (LODs), both immobilised antibody-based (direct) and immobilised antigen-based (competitive) assay setups were applied. Immunoreagents were immobilised on epoxy-, amino-, and carboxyl-functionalised sensor surfaces, and by optimising the immobilisation methods, standard sigmoid curves were obtained in both sensor formats. An outstanding LOD of 0.002 pg/mL was obtained for ZON in the competitive immunosensor setup with a dynamic detection range between 0.01 and 1 pg/mL ZON concentrations, depending on the covalent immobilisation method applied. This corresponds to a five orders of magnitude improvement in detectability of ZON relative to the previously developed enzyme-linked immonosorbent assay (ELISA) method. The selectivity of the immunosensor for ZON was demonstrated with structural analogues (α-zearalenol, α-zearalanol, and β-zearalanol) and structurally unrelated mycotoxins. The method was found to be applicable in maize extract using acetonitrile as the organic solvent, upon a dilution rate of 1:10,000 in buffer. Thus, the OWLS immunosensor method developed appears to be suitable for the quantitative determination of ZON in aqueous medium. The new technique can widen the range of sensoric detection methods of ZON for surveys in food and environmental safety assessment.

scholarly journals Chiral Hybrid Nanosystems and Their Biosensing Applications

2020 ◽  
Author(s):  
Vladimir E. Bochenkov ◽  
Tatyana I. Shabatina
Keyword(s):  
Refractive Index ◽  
Electric Fields ◽  
Metal Nanostructures ◽  
Order Structure ◽  
Molecular Adsorption ◽  
Label Free ◽  
Label Free Detection ◽  
Hybrid Nanosystems ◽  
Local Refractive Index

The presented chapter is devoted to chiral biosensing using various metal nanostructures and their hybrid nanosystems with optically active bio- and organic molecules. Plasmonic nanosystems and nanostructures provide an excellent platform for label-free detection of molecular adsorption by detecting tiny changes in the local refractive index or amplification of light-induced processes in biomolecules. Based on recent theoretical and experimental developments in plasmon-enhanced local electric fields, we consider the main types of molecular-plasmonic hybrid systems capable of generating an amplified chiroptical signal for such applications as detecting the presence of certain biomolecules and (in some cases) determination of their orientation and higher-order structure.

Ultrasensitive and label-free detection of creatine based on CdO nanoparticles: a real sample approach

2017 ◽  
Vol 41 (14) ◽  
pp. 6667-6677 ◽  
Author(s):  
Mohammed M. Rahman ◽  
Mohammad Musarraf Hussain ◽  
Abdullah M. Asiri
Keyword(s):  
Dynamic Range ◽  
Limit Of Detection ◽  
Cadmium Oxide ◽  
Real Sample ◽  
Label Free ◽  
Long Term Stability ◽  
Label Free Detection ◽  
Cdo Nanoparticles ◽  
Low Dimensional

Low-dimensional cadmium oxide nanoparticles (CdO NPs) were prepared by a facile wet-chemical method, which later electrochemically investigated for the determination of selective creatine and measured the analytical sensor parameters such as sensitivity, limit of detection (LOD), linear dynamic range (LDR), long-term stability, and real-sample validation.

A fluorescent probe with restricted intramolecular rotation-induced emission for label-free detection of mercury ions

The Analyst ◽  
2014 ◽  
Vol 139 (13) ◽  
pp. 3369 ◽  
Author(s):  
Shengliang Li ◽  
Hua Deng ◽  
Weipeng Cao ◽  
Chunqiu Zhang ◽  
Shubin Jin ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Label Free ◽  
Mercury Ions ◽  
Label Free Detection ◽  
Intramolecular Rotation

DNA functionalized gold nanorods/nanoplates assembly as sensitive LSPR-based sensor for label-free detection of mercury ions

2013 ◽  
Vol 110 ◽  
pp. 485-488 ◽  
Author(s):  
Dandan Li ◽  
Guangchao Zheng ◽  
Xiaofeng Ding ◽  
Jin Wang ◽  
Jinhuai Liu ◽  
...  
Keyword(s):  
Gold Nanorods ◽  
Label Free ◽  
Mercury Ions ◽  
Label Free Detection

Label-free detection of cytochrome C by a conducting polymer-based impedimetric screen-printed aptasensor

2018 ◽  
Vol 42 (8) ◽  
pp. 6034-6039 ◽  
Author(s):  
Atefeh Shafaat ◽  
Farnoush Faridbod ◽  
Mohammad Reza Ganjali
Keyword(s):  
Cytochrome C ◽  
Conducting Polymer ◽  
Cell Apoptosis ◽  
Label Free ◽  
Label Free Detection ◽  
Screen Printed

In this study we have introduced a new sensitive and selective biosensor for the determination of cytochrome C (Cyt C) as a biomarker for cell apoptosis.

Label-free detection of fibrinogen based on the fibrinogen-enhanced peroxidase activity of a fibrinogen–hemin composite

The Analyst ◽  
2018 ◽  
Vol 143 (3) ◽  
pp. 725-730 ◽  
Author(s):  
Tingting Hou ◽  
Yuanfu Zhang ◽  
Tao Wu ◽  
Meifeng Wang ◽  
Yinghong Zhang ◽  
...  
Keyword(s):  
Peroxidase Activity ◽  
Colorimetric Method ◽  
Label Free ◽  
Label Free Detection

A simple, label-free colorimetric method for the determination of fibrinogen (Fib) in plasma is presented.

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