SERS-based lateral flow assay for quantitative detection of C-reactive protein as an early bio-indicator of a radiation-induced inflammatory response in nonhuman primates

The Analyst ◽  
2018 ◽  
Vol 143 (9) ◽  
pp. 2115-2121 ◽  
Author(s):  
Zhen Rong ◽  
Rui Xiao ◽  
Shuang Xing ◽  
Guolin Xiong ◽  
Zuyin Yu ◽  
...  

We demonstrate a SERS-based lateral flow assay for rapid and quantitative detection of CRP and its potential for in-field evaluation of acute radiation syndrome.

2008 ◽  
Vol 336 (1) ◽  
pp. 30-36 ◽  
Author(s):  
Wingman Leung ◽  
Cangel Puiyee Chan ◽  
Timothy H. Rainer ◽  
Margaret Ip ◽  
George W.H. Cautherley ◽  
...  

2019 ◽  
Vol 35 (3) ◽  
pp. 257-263 ◽  
Author(s):  
Nan ZHAN ◽  
Yang ZHOU ◽  
Laibao MEI ◽  
Yuwang HAN ◽  
Hongman ZHANG

2019 ◽  
Vol 6 (1) ◽  
Author(s):  
Kyung Mi Park ◽  
Da Jung Chung ◽  
Mijin Choi ◽  
Taejoon Kang ◽  
Jinyoung Jeong

Abstract A fluorescent fullerene nanoparticle (NP)-based lateral flow immunochromatographic assay (LFIA) was developed for the rapid and quantitative detection of C-reactive protein (CRP) in serum. The polyclonal CRP-antibody-conjugated fullerene NPs were simply prepared by 1-ethyl-3-(3-dimethyllaminopropyl)-carbodiimide hydrochloride coupling after carboxylation of fluorescent fullerene NPs. By applying the CRP-antibody-conjugated fullerene NPs to a lateral flow test strip, quantitative analysis of CRP in serum was possible at a concentration range of 0.1–10 ng/ml within 15 min. We anticipate that this novel fluorescent fullerene NP-based LFIA can be useful for the rapid and accurate sensing of biological and chemical species, contributing to the disease diagnosis and prognosis, environmental monitoring, and food safety.


2020 ◽  
Vol 22 (11) ◽  
pp. 617-629
Author(s):  
Ngoc Linh Phung ◽  
Johanna G. Walter ◽  
Rebecca Jonczyk ◽  
Lisa K. Seiler ◽  
Thomas Scheper ◽  
...  

RSC Advances ◽  
2021 ◽  
Vol 11 (45) ◽  
pp. 28388-28394
Author(s):  
Renzhu Pang ◽  
Qunyan Zhu ◽  
Jia Wei ◽  
Yaoqi Wang ◽  
Fengqin Xu ◽  
...  

A gold-nanorod-based lateral flow immunoassay for rapid and quantitative detection of CRP by simultaneously monitoring the colorimetric and temperature signals.


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