Coordination polymer hybridized Au nanocages: a nanoplatform for dual-modality imaging guided near-infrared driven photothermal therapy in vivo

2017 ◽  
Vol 5 (44) ◽  
pp. 8761-8769 ◽  
Author(s):  
Congyang Yan ◽  
Lili Cui ◽  
Qi Yang ◽  
Xiaobao Zhou ◽  
Lixing Pan ◽  
...  

Coordination polymer hybridized Au nanocages (AuNC@CPs) were prepared, which were used for near-infrared (NIR)-driven photothermal therapy (PTT) guided by photoacoustic (PA) and magnetic resonance (MR) imaging in vivo.

2016 ◽  
Vol 52 (86) ◽  
pp. 12745-12748 ◽  
Author(s):  
Hualong Fu ◽  
Cheng Peng ◽  
Zhigang Liang ◽  
Jiapei Dai ◽  
Boli Liu ◽  
...  

Three fluorinated (19F or 18F) small molecules were evaluated as fluorescent or radiolabeled probes for Aβ deposits in the brain.


Nanoscale ◽  
2021 ◽  
Vol 13 (9) ◽  
pp. 5077-5093 ◽  
Author(s):  
Zhou Sha ◽  
Shuguang Yang ◽  
Liwen Fu ◽  
Mengru Geng ◽  
Jiani Gu ◽  
...  

The as-prepared nanoparticles integrate bone targeted chem-chemodynamic combination therapy and dual-modality computed tomography/magnetic resonance (CT/MR) imaging into a single platform.


Cytotherapy ◽  
2014 ◽  
Vol 16 (5) ◽  
pp. 699-710 ◽  
Author(s):  
Yu-Chen Chen ◽  
Song Wen ◽  
Song-An Shang ◽  
Ying Cui ◽  
Bing Luo ◽  
...  

2020 ◽  
Vol 12 (1) ◽  
Author(s):  
Songtao Zhang ◽  
Longhai Jin ◽  
Jianhua Liu ◽  
Yang Liu ◽  
Tianqi Zhang ◽  
...  

AbstractIn spite of the tumor microenvironments responsive cancer therapy based on Fenton reaction (i.e., chemodynamic therapy, CDT) has been attracted more attentions in recent years, the limited Fenton reaction efficiency is the important obstacle to further application in clinic. Herein, we synthesized novel FeO/MoS2 nanocomposites modified by bovine serum albumin (FeO/MoS2-BSA) with boosted Fenton reaction efficiency by the synergistic effect of co-catalyze and photothermal effect of MoS2 nanosheets triggered by the second near-infrared (NIR II) light. In the tumor microenvironments, the MoS2 nanosheets not only can accelerate the conversion of Fe3+ ions to Fe2+ ions by Mo4+ ions on their surface to improve Fenton reaction efficiency, but also endow FeO/MoS2-BSA with good photothermal performances for photothermal-enhanced CDT and photothermal therapy (PTT). Consequently, benefiting from the synergetic-enhanced CDT/PTT, the tumors are eradicated completely in vivo. This work provides innovative synergistic strategy for constructing nanocomposites for highly efficient CDT.


2015 ◽  
Vol 2 (Suppl 1) ◽  
pp. A89 ◽  
Author(s):  
Charalmpos Tsoukalas ◽  
Gautier Laurent ◽  
Gloria Jiménez Sánchez ◽  
Theodoros Tsotakos ◽  
Rana Bazzi ◽  
...  

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