Near-infrared conjugated polymers for photoacoustic imaging-guided photothermal/chemo combination therapy

2017 ◽  
Vol 5 (27) ◽  
pp. 5479-5487 ◽  
Author(s):  
Yue Cao ◽  
Yannan Wu ◽  
Guannan Wang ◽  
Jingwen Yi ◽  
Chunlei Yu ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Combination Therapy ◽  
Conjugated Polymers ◽  
Conversion Efficiency ◽  
Infrared Absorption ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Photoacoustic Imaging ◽  
Imaging Agents ◽  
New Generation

Conjugated polymers with intensive near-infrared absorption and high photothermal conversion efficiency have emerged as a new generation of photothermal therapy and photoacoustic imaging agents for cancer therapy.

scholarly journals Polydopamine-decorated tobacco mosaic virus for photoacoustic/magnetic resonance bimodal imaging and photothermal cancer therapy

Nanoscale ◽  
2019 ◽  
Vol 11 (19) ◽  
pp. 9760-9768 ◽  
Author(s):  
He Hu ◽  
Qi Yang ◽  
Simona Baroni ◽  
Hong Yang ◽  
Silvio Aime ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Cancer Therapy ◽  
Tobacco Mosaic Virus ◽  
Mosaic Virus ◽  
Conversion Efficiency ◽  
Infrared Absorption ◽  
Near Infrared ◽  
Photothermal Conversion ◽  
Bimodal Imaging ◽  
Good Biocompatibility

The Gd-TMV–PDA nanotheranostic reagents demonstrated highly r1-relaxivity of ∼80 mM−1 s−1 at 60 MHz, strong near-infrared absorption with high photothermal conversion efficiency (28.9%), excellent photoacoustic contrast and good biocompatibility.

Novel phthalocyanine-based polymeric micelles with high near-infrared photothermal conversion efficiency under 808 nm laser irradiation for in vivo cancer therapy

2019 ◽  
Vol 7 (14) ◽  
pp. 2247-2251 ◽  
Author(s):  
Lu Li ◽  
Qingzhu Yang ◽  
Lei Shi ◽  
Nannan Zheng ◽  
Zeyu Li ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Cancer Cells ◽  
Laser Irradiation ◽  
Conversion Efficiency ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Polymeric Micelles ◽  
Photothermal Conversion ◽  
Phthalocyanine Molecule

Novel phthalocyanine molecule 4OCSPC with deep NIR absorbance showed excellent photothermal therapy property for cancer cells.

Silicon nanowires decorated with gold nanoparticles via in situ reduction for photoacoustic imaging-guided photothermal cancer therapy

2019 ◽  
Vol 7 (28) ◽  
pp. 4393-4401 ◽  
Author(s):  
Lina Sun ◽  
Ying Chen ◽  
Fei Gong ◽  
Qian Dang ◽  
Guangzhen Xiang ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Cancer Therapy ◽  
Solid Tumors ◽  
Silicon Nanowires ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Photoacoustic Imaging ◽  
In Situ Reduction ◽  
Great Progress

Photothermal therapy (PTT) in the first near-infrared (NIR-I) window has made great progress in the treatment of solid tumors, while only a few PTT agents in the second NIR (NIR-II) region have been studied.

Bi19S27I3 nanorods: a new candidate for photothermal therapy in the first and second biological near-infrared windows

Nanoscale ◽  
2021 ◽  
Author(s):  
Jinsong Xiong ◽  
Qinghuan Bian ◽  
Shuijin Lei ◽  
Yatian Deng ◽  
Kehan Zhao ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Research Interest ◽  
The Past ◽  
Nir Light ◽  
Considerable Research ◽  
Key Factor

Near-infrared (NIR) light induced photothermal cancer therapy using nanomaterials as photothermal agents has attracted considerable research interest over the past few years. As the key factor in the photothermal therapy...

Pyrazino[2,3-g]quinoxaline-Based Nanoparticles as Near-Infrared Phototheranostic Agents for Efficient Photoacoustic-Imaging-Guided Photothermal Therapy

2021 ◽  
Vol 4 (2) ◽  
pp. 2019-2029
Author(s):  
Li-Peng Zhang ◽  
Lin Kang ◽  
Xianqiang Li ◽  
Shiyang Liu ◽  
Tianlong Liu ◽  
...  
Keyword(s):  
Photothermal Therapy ◽  
Near Infrared ◽  
Photoacoustic Imaging

scholarly journals Boosting Chemodynamic Therapy by the Synergistic Effect of Co-Catalyze and Photothermal Effect Triggered by the Second Near-Infrared Light

2020 ◽  
Vol 12 (1) ◽  
Author(s):  
Songtao Zhang ◽  
Longhai Jin ◽  
Jianhua Liu ◽  
Yang Liu ◽  
Tianqi Zhang ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Bovine Serum Albumin ◽  
Synergistic Effect ◽  
Bovine Serum ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Infrared Light ◽  
Photothermal Effect ◽  
Reaction Efficiency

AbstractIn spite of the tumor microenvironments responsive cancer therapy based on Fenton reaction (i.e., chemodynamic therapy, CDT) has been attracted more attentions in recent years, the limited Fenton reaction efficiency is the important obstacle to further application in clinic. Herein, we synthesized novel FeO/MoS2 nanocomposites modified by bovine serum albumin (FeO/MoS2-BSA) with boosted Fenton reaction efficiency by the synergistic effect of co-catalyze and photothermal effect of MoS2 nanosheets triggered by the second near-infrared (NIR II) light. In the tumor microenvironments, the MoS2 nanosheets not only can accelerate the conversion of Fe3+ ions to Fe2+ ions by Mo4+ ions on their surface to improve Fenton reaction efficiency, but also endow FeO/MoS2-BSA with good photothermal performances for photothermal-enhanced CDT and photothermal therapy (PTT). Consequently, benefiting from the synergetic-enhanced CDT/PTT, the tumors are eradicated completely in vivo. This work provides innovative synergistic strategy for constructing nanocomposites for highly efficient CDT.

MnO2-Coated Porous Pt@CeO2 Core-Shell Nanostructures for Photoacoustic Imaging-Guided Tri-modal Cancer Therapy

Nanoscale ◽  
2021 ◽  
Author(s):  
Qing Xu ◽  
Danyang Li ◽  
Haijun Zhou ◽  
Biaoqi Chen ◽  
Junlei Wang ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Conversion Efficiency ◽  
Photoacoustic Imaging ◽  
Core Shell ◽  
Photothermal Conversion ◽  
The Core ◽  
Shell Nanostructures

We describe the synthesis of MnO2-coated porous Pt@CeO2 core–shell nanostructures (Pt@CeO2@MnO2) as a new theranostic nano-platform. The porous Pt cores endow the core–shell nanostructures with high photothermal conversion efficiency (80%)...

scholarly journals Melanoma Cancer Therapy Using PEGylated Nanoparticles and Semiconductor Laser

2021 ◽  
Author(s):  
Abdorreza Asrar ◽  
Zahra Sobhani ◽  
Mohammad Ali Behnam
Keyword(s):  
Cancer Therapy ◽  
Laser Beam ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Histopathological Study ◽  
Melanoma Tumor ◽  
Tio2 Nps ◽  
Melanoma Cancer ◽  
Murine Melanoma ◽  
Pegylated Nanoparticles

Purpose: Photothermal therapy is a procedure that converts laser beam energy to heat so can disturb tumor cells. Carbon nanotubes (CNTs) have unique properties in absorption optical energy and could change optical power into heat in photothermal therapy procedures. Additionally, titanium dioxide (TiO2) NPs have a unique feature in absorbing and scattering light. Therefore, these mentioned NPs could play a synergistic role in the photothermal therapy method. Methods: CNTs and TiO2 NPs were injected into the melanoma tumor sites of cancerous mice. Then sites were excited using the laser beam (λ= 808nm, P= 2W, and I= 4W/cm2). Injected NPs caused hyperthermia in solid tumors. Tumor size assay, statistical analysis, and histopathological study of the treated cases were performed to assess the role of mentioned NPs in photothermal therapy of murine melanoma cancer. Results: The results showed that CNTs performed better than TiO2 NPs in destroying murine melanoma cancer cells in animals. Conclusion: The present study compared the photothermal activity of excited CNTs and TiO2 NPs in cancer therapy at the near-infrared spectrum of light. Tumors were destroyed selectively because of their weakened heat resistance versus normal tissue. Photothermal therapy of malignant melanoma through CNTs caused remarkable necrosis into the tumor tissues versus TiO2 NPs.

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