Rapid delivery of paclitaxel with an organic solvent-free system based on a novel cell penetrating peptide for suppression of tumor growth

2017 ◽  
Vol 5 (37) ◽  
pp. 7768-7774
Author(s):  
Yuping Wei ◽  
Liang Zhang ◽  
Yankai Fu ◽  
Xia Xu
Keyword(s):  
Tumor Growth ◽  
Organic Solvent ◽  
Delivery System ◽  
Hela Cells ◽  
Cell Penetrating Peptide ◽  
Free System ◽  
Tail Vein ◽  
Tail Vein Injection ◽  
Cell Penetrating ◽  
Solvent Free System

PTX is rapidly translocated into HeLa cells with the help of R7. The intracellular PTX concentration of R7/PTX complex group is 3 fold that of the free PTX group. This delivery system does not contain any organic solvent. The tumor growth is significantly suppressed by a tail vein injection of the R7/PTX complex.

Cell-penetrating peptide mimicking polymer-based combined delivery of paclitaxel and siRNA for enhanced tumor growth suppression

2012 ◽  
Vol 434 (1-2) ◽  
pp. 488-493 ◽  
Author(s):  
Yeon Lim Jang ◽  
Ui Jeong Yun ◽  
Min Sang Lee ◽  
Myung Goo Kim ◽  
Sohee Son ◽  
...  
Keyword(s):  
Tumor Growth ◽  
Growth Suppression ◽  
Cell Penetrating Peptide ◽  
Cell Penetrating ◽  
Tumor Growth Suppression

Enhanced activity of vancomycin by encapsulation in hybrid magnetic nanoparticles conjugated to a cell-penetrating peptide

Nanoscale ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 3855-3870 ◽  
Author(s):  
Wenjie Zhang ◽  
Reza Taheri-Ledari ◽  
Zoleikha Hajizadeh ◽  
Ehsan Zolfaghari ◽  
Mohammad Reza Ahghari ◽  
...  
Keyword(s):  
Magnetic Nanoparticles ◽  
Delivery System ◽  
Cell Penetrating Peptide ◽  
Enhanced Activity ◽  
Cell Penetrating ◽  
A Cell ◽  
Antibiotic Delivery

We describe a novel antibiotic delivery system based on magnetic nanoparticles (NPs) conjugated to a cell-penetrating peptide (CPP).

scholarly journals Designing and enhancing the antifungal activity of corneal specific cell penetrating peptide using gelatin hydrogel delivery system

2019 ◽  
Vol Volume 14 ◽  
pp. 605-622 ◽  
Author(s):  
Chatterjee Amit ◽  
Shalini Muralikumar ◽  
Sargunam Janaki ◽  
Meena Lakshmipathy ◽  
Kulandhai Lilly Therese ◽  
...  
Keyword(s):  
Antifungal Activity ◽  
Delivery System ◽  
Cell Penetrating Peptide ◽  
Specific Cell ◽  
Gelatin Hydrogel ◽  
Cell Penetrating

Dual-functionalized calcium carbonate based gene delivery system for efficient gene delivery

RSC Advances ◽  
2014 ◽  
Vol 4 (73) ◽  
pp. 38623-38629 ◽  
Author(s):  
Chao-Qun Wang ◽  
Meng-Qing Gong ◽  
Jin-Long Wu ◽  
Ren-Xi Zhuo ◽  
Si-Xue Cheng
Keyword(s):  
Calcium Carbonate ◽  
Gene Delivery ◽  
Delivery System ◽  
Gene Transfection ◽  
Cell Penetrating Peptide ◽  
Gene Delivery System ◽  
Dna Nanoparticles ◽  
Efficient Gene ◽  
Cell Penetrating ◽  
A Cell

Dual-functionalized KALA/PS/CaCO3/DNA nanoparticles containing a cell penetrating peptide (KALA) and protamine sulfate (PS) could effectively mediate gene transfection at a low DNA concentration.

Enzyme-triggered delivery of chlorambucil from conjugates based on the cell-penetrating peptide BP16

2015 ◽  
Vol 13 (5) ◽  
pp. 1470-1480 ◽  
Author(s):  
Marta Soler ◽  
Marta González-Bártulos ◽  
Eduard Figueras ◽  
Xavi Ribas ◽  
Miquel Costas ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Cells ◽  
Drug Delivery System ◽  
Delivery System ◽  
Cell Penetrating Peptide ◽  
Cell Penetrating ◽  
Uptake And Release

The combination of the cell-penetrating peptide BP16 with the enzymatic cleavable sequence Gly-Phe-Leu-Gly constitutes a drug delivery system for the effective uptake and release of chlorambucil in cancer cells.

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