An activatable anticancer polymer–drug conjugate based on the self-immolative azobenzene motif

2017 ◽  
Vol 5 (24) ◽  
pp. 4574-4578 ◽  
Author(s):  
Taejun Eom ◽  
Wonjae Yoo ◽  
Yong-Deok Lee ◽  
Jae Hyung Park ◽  
Youngson Choe ◽  
...  
Keyword(s):  
Anticancer Drug ◽  
Cellular Uptake ◽  
Graft Copolymer ◽  
The Self ◽  
Side Chain ◽  
Synthetic Graft ◽  
Drug Conjugate ◽  
Self Immolation ◽  
Azobenzene Groups

Triggered cellular uptake of a synthetic graft copolymer carrying an anticancer drug is achieved through self-immolation of the side-chain azobenzene groups.

scholarly journals Violently Peaceful: Tibetan Self-Immolation and the Problem of the Non/Violence Binary

Open Theology ◽  
2015 ◽  
Vol 1 (1) ◽  
Author(s):  
John Soboslai
Keyword(s):  
Hannah Arendt ◽  
The Self ◽  
Self Immolation ◽  
Ethical Systems

AbstractThe paper investigates the conceptual dichotomy of violence and nonviolence in reference to the self-immolations that have been taking place in Tibet for the last several years. First using the insights of Hannah Arendt to distinguish between the categories of violent, nonviolent and peaceful, I approach the question of violence as the problem of acts that transgress prohibitions against causing harm. Using that heuristic, I examine the ways multiple ethical systems are vying for recognition regarding the selfimmolations, and how a certain Buddhist ambivalence around extreme acts of devotion complicate any easy designations of the act as ‘violent’ or ‘nonviolent’. I conclude by suggesting how any such classification inculcates us into questions of power and assertions of appropriate authority.

Azobenzene-functionalized graphene nanoribbons: bottom-up synthesis, photoisomerization behaviour and self-assembled structures

2020 ◽  
Vol 8 (31) ◽  
pp. 10837-10843
Author(s):  
Zhichun Shangguan ◽  
Chunyang Yu ◽  
Chen Li ◽  
Xianhui Huang ◽  
Yiyong Mai ◽  
...  
Keyword(s):  
Self Assembly ◽  
Graphene Nanoribbons ◽  
The Self ◽  
Functionalized Graphene ◽  
Bottom Up ◽  
Self Assembled ◽  
Azobenzene Groups

We show the strategy of introducing azobenzene groups into graphene nanoribbons (GNRs), which not only endows GNRs with fast photo-responsiveness but also induces the self-assembly of the GNRs into ultra-long nanowires.

scholarly journals Correction to “Macromolecular Architecture and Encapsulation of the Anticancer Drug Everolimus Control the Self-Assembly of Amphiphilic Polypeptide-Containing Hybrids”

2020 ◽  
Vol 21 (4) ◽  
pp. 1644-1644
Author(s):  
Anastasis Karatzas ◽  
Johannes S. Haataja ◽  
Dimitrios Skoulas ◽  
Panayiotis Bilalis ◽  
Spyridon Varlas ◽  
...  
Keyword(s):  
Anticancer Drug ◽  
Self Assembly ◽  
The Self ◽  
Macromolecular Architecture

scholarly journals Molecular dynamics simulations of the self-organization of side-chain decorated polyaromatic conjugation molecules: phase separated lamellar and columnar structures and dispersion behaviors in toluene solvent

RSC Advances ◽  
2018 ◽  
Vol 8 (20) ◽  
pp. 11134-11144 ◽  
Author(s):  
Lanyan He ◽  
Pingmei Wang ◽  
Lipeng He ◽  
Zhou Qu ◽  
Jianhui Luo ◽  
...  
Keyword(s):  
Molecular Dynamics ◽  
Molecular Dynamics Simulations ◽  
Molecular Dynamic ◽  
Md Simulations ◽  
The Self ◽  
Self Organization ◽  
Side Chain ◽  
Dynamics Simulations

The self-organization of five model side-chain decorated polyaromatic asphaltene molecules with or without toluene solvent was investigated by means of molecular dynamic (MD) simulations.

Construction of micelles based on biocompatible pseudo-graft polymers via β-cyclodextrin/cholesterol interaction for protein delivery

RSC Advances ◽  
2014 ◽  
Vol 4 (77) ◽  
pp. 40882-40891 ◽  
Author(s):  
Hui Han ◽  
De-E Liu ◽  
Hongguang Lu ◽  
Wen-Xing Gu ◽  
Hui Gao
Keyword(s):  
Aspartic Acid ◽  
Graft Copolymer ◽  
Self Assembly ◽  
Protein Delivery ◽  
Inclusion Complexation ◽  
The Self ◽  
Graft Polymers ◽  
Copolymer Micelle

A pseudo-graft copolymer micelle was constructed from the self-assembly of (6-(2-aminoethyl)-amino-6-deoxy)-cyclodextrin (β-CDen)-modified poly(aspartic acid) (PASP-CD) with cholesterol-modified poly(d,l-lactide) (PLA-Chol) using host–guest inclusion complexation in water.

Syntheses and properties of polyurethanes containing side-chain azobenzene groups

2003 ◽  
Vol 52 (5) ◽  
pp. 658-663 ◽  
Author(s):  
Mi-Ra Kim ◽  
Phan-Seok Kim ◽  
Eun-Hee Kang ◽  
Chang-Sik Ha ◽  
Jin-Kook Lee
Keyword(s):  
Side Chain ◽  
Azobenzene Groups

scholarly journals Influence of Side Chain Length on the Self-Assembly of Hairy-Rod Poly(9,9-dialkylfluorene)s in the Poor Solvent Methylcyclohexane

2007 ◽  
Vol 40 (26) ◽  
pp. 9398-9405 ◽  
Author(s):  
M. Knaapila ◽  
F. B. Dias ◽  
V. M. Garamus ◽  
L. Almásy ◽  
M. Torkkeli ◽  
...  
Keyword(s):  
Chain Length ◽  
Self Assembly ◽  
The Self ◽  
Side Chain ◽  
Side Chain Length ◽  
The Poor ◽  
Poor Solvent

scholarly journals Relationship between Side-Chain Polarity and the Self-Assembly Characteristics of Perylene Diimide Derivatives in Aqueous Solution

ChemistryOpen ◽  
2017 ◽  
Vol 6 (2) ◽  
pp. 266-272 ◽  
Author(s):  
Jurgen Schill ◽  
Lech-Gustav Milroy ◽  
Jody A. M. Lugger ◽  
Albertus P. H. J. Schenning ◽  
Luc Brunsveld
Keyword(s):  
Aqueous Solution ◽  
Self Assembly ◽  
The Self ◽  
Perylene Diimide ◽  
Side Chain ◽  
Perylene Diimide Derivatives
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