The improvement of corrosion resistance, biocompatibility and osteogenesis of the novel porous Mg–Nd–Zn alloy

2017 ◽  
Vol 5 (36) ◽  
pp. 7661-7674 ◽  
Author(s):  
Wei Liu ◽  
Jiaxing Wang ◽  
Guofeng Jiang ◽  
Jinxiao Guo ◽  
Qiuyan Li ◽  
...  
Keyword(s):  
Corrosion Resistance ◽  
Bone Repair ◽  
Repair Material ◽  
The Novel ◽  
Zn Alloy ◽  
Bone Repair Material

A magnesium scaffold is a promising biodegradable bone repair material.

Copper-doped mesoporous bioactive glass endows magnesium based scaffold with antibacterial activity and corrosion resistance

2021 ◽  
Author(s):  
Youwen Yang ◽  
changfu lu ◽  
mingli yang ◽  
dongsheng wang ◽  
Shuping Peng ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Corrosion Resistance ◽  
Bacterial Infection ◽  
Bioactive Glass ◽  
Bone Repair ◽  
Repair Material ◽  
Metal Element ◽  
Biodegradable Magnesium ◽  
Bone Repair Material ◽  
Mesoporous Bioactive Glass

Biodegradable magnesium (Mg) scaffold as bone repair material is desired to own antibacterial function to reduce the risk of bacterial infection. The alloying with antibacterial metal element such as copper...

scholarly journals The Preparation andIn VitroEvaluations of a Nanoscaled Injectable Bone Repair Material

2015 ◽  
Vol 2015 ◽  
pp. 1-8
Author(s):  
Xinhui Liu ◽  
Chao Zhu ◽  
Yijiong Li ◽  
Yueling Yan ◽  
Chuanyong Hou ◽  
...  
Keyword(s):  
Laser Scanning ◽  
Bone Repair ◽  
Cell Attachment ◽  
Repair Material ◽  
Cellular Functions ◽  
Repair Materials ◽  
Proliferation And Differentiation ◽  
Negative Effect ◽  
Bone Repair Material

There are usually two forms of bone repair materials, block and granular, for common clinical use. This paper describes a novel injectable material, nano-HA/collagen/alginate (nHAC/Alg) composite biomaterial, including its preparation and evaluationsin vitro. Based on the idea of bionics and the study of collagen/calcium phosphate salt composite materials, the injectable bone repair material was developed. Then, human bone marrow stem cells (hBMSCs) were cultured on the nHAC/Alg material. The cell attachment, proliferation, and differentiation were evaluated with inverted microscope, scanning electron microscope, laser scanning confocal microscope, 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide (MTT) analysis, and alkaline phosphatase (ALP) test. The results showed that nHAC/Alg not only had no negative effect on cellular functions but also promotes cell proliferation and differentiation into osteogenic cells, which suggests that the nanoscaled injectable bone repair material has good clinical application prospects for bone repair.

Osteogenic properties of bioactive sodium titanate/titanium oxide composite coating prepared by anodic oxidation in NaOH electrolyte

2021 ◽  
Author(s):  
Yuqiang Guo ◽  
Boyao Wu ◽  
Yi Hu ◽  
Rui Zuo ◽  
Xugang Lu ◽  
...  
Keyword(s):  
Titanium Oxide ◽  
Composite Coating ◽  
Anodic Oxidation ◽  
Bone Repair ◽  
Oxide Coating ◽  
Sodium Titanate ◽  
Repair Material ◽  
Oxide Composite ◽  
Titanium Oxide Coating ◽  
Bone Repair Material

Our sodium titanate/titanium oxide coating has excellent osteogenic performance and has potential to be used as a bone repair material.

A co-dispersed nanosystem from strontium-anchored reduced graphene oxide to enhance bioactivity and mechanical property in polymer scaffolds

2021 ◽  
Author(s):  
Fangwei Qi ◽  
chen wang ◽  
Shuping Peng ◽  
Cijun Shuai ◽  
Wenjing Yang ◽  
...  
Keyword(s):  
Mechanical Property ◽  
Graphene Oxide ◽  
Reduced Graphene Oxide ◽  
Bone Repair ◽  
Repair Material ◽  
Polymer Scaffolds ◽  
Reduced Graphene ◽  
Good Biocompatibility ◽  
Bone Repair Material

Poly (L-lactide) (PLLA) is a promising bone repair material owing to its good biocompatibility and natural degradability, but the lacked bioactivity and insufficient mechanical property restrict its further application. Strontium...

scholarly journals Preparation, bioactivity and mechanism of nano-hydroxyapatite/sodium alginate/chitosan bone repair material

2017 ◽  
Vol 16 (1) ◽  
pp. 28-35 ◽  
Author(s):  
Jianguo Liao ◽  
Yanqun Li ◽  
Haiyan Li ◽  
Jingxian Liu ◽  
Yufen Xie ◽  
...  
Keyword(s):  
Compressive Strength ◽  
Sodium Alginate ◽  
Bone Repair ◽  
Weight Bearing ◽  
Synthesis Method ◽  
Repair Material ◽  
In Vitro Bioactivity ◽  
Promote Cell Proliferation ◽  
Bone Repair Material

Background: As the major inorganic component of natural bone, nano-hydroxyapatite (n-HA) on its own is limited in its use in bone repair, due to its brittleness. Chitosan (CS) and sodium alginate (SAL) are used to reduce its brittleness and tendency to degradation. However, the compressive strength of the composite is still low, and its biological performance needs further study. Methods: Nano-hydroxyapatite/sodium alginate/chitosan (n-HA/SAL/CS) composite was prepared via an in situ synthesis method. Further, we prepared the n-HA/SAL/CS self-setting bone repair material by mixing n-HA/SAL/CS powder with a curing liquid (20 wt.% citric acid). In addition, the in vitro bioactivity and cell cytotoxicity were also explored. Results: Transmission electron microscopy photos revealed that the n-HA crystals were uniformly distributed throughout the polymer matrix. Infrared IR spectroscopy indicated that the HA interacted with the COO− of SAL and NH2− of CS. The compressive strength of the n-HA/SAL/CS bone cement was 34.3 MPa and matched the demands of weight-bearing bones. Soaking in vitro in simulated body fluid demonstrated that the composite material had reasonably good bioactivity, while cytotoxicity tests indicated that the n-HA/SAL/CS cement could promote cell proliferation and was biocompatible. Conclusions: Compressive strength of n-HA/SAL/CS can satisfy the needs of cancellous bone, and in vitro bioactivity and cytotoxicity tests results indicated that the n-HA/SAL/CS composite could act as an optimal bone repair material.

Composites of poly(L -lactide-trimethylene carbonate-glycolide) and surface modified SBA-15 as bone repair material

2018 ◽  
Vol 29 (4) ◽  
pp. 1322-1333 ◽  
Author(s):  
Jielin Wang ◽  
Beibei Du ◽  
Zhongyong Fan ◽  
Suming Li ◽  
Peng Yun ◽  
...  
Keyword(s):  
Bone Repair ◽  
Repair Material ◽  
Trimethylene Carbonate ◽  
Surface Modified ◽  
Bone Repair Material

Magnesium-based layered double hydroxide nanosheets: a new bone repair material with unprecedented osteogenic differentiation performance

Nanoscale ◽  
2020 ◽  
Vol 12 (37) ◽  
pp. 19075-19082
Author(s):  
Yingjie Wang ◽  
Xuan Mei ◽  
Yanyan Bian ◽  
Tingting Hu ◽  
Xisheng Weng ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Osteogenic Differentiation ◽  
Layered Double Hydroxide ◽  
Bone Repair ◽  
Repair Material ◽  
Double Hydroxide ◽  
Bone Repair Material

Monolayer magnesium-based layered double hydroxide nanosheets loaded with alendronate were fabricated, which showed unprecedented osteogenic differentiation and bone regeneration performance.

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