Development of a unique family of two-photon full-color-tunable fluorescent materials for imaging in live subcellular organelles, cells, and tissues

2017 ◽  
Vol 5 (13) ◽  
pp. 2436-2444 ◽  
Author(s):  
Hua Chen ◽  
Yonghe Tang ◽  
Huiming Shang ◽  
Xiuqi Kong ◽  
Rui Guo ◽  
...  
Keyword(s):  
Optical Property ◽  
Rational Design ◽  
Biological Imaging ◽  
Imaging Studies ◽  
Design Synthesis ◽  
Subcellular Organelles ◽  
Two Photon ◽  
Full Color ◽  
Color Tunable ◽  
Fluorescent Materials

We outline the rational design, synthesis, optical property studies, and biological imaging studies of a unique family of two-photon full-color-tunable functional fluorescent materials.

A general strategy for development of a single benzene fluorophore with full-color-tunable, environmentally insensitive, and two-photon solid-state emission

2019 ◽  
Vol 55 (76) ◽  
pp. 11462-11465 ◽  
Author(s):  
Zhen Xiang ◽  
Zhi-Yao Wang ◽  
Tian-Bing Ren ◽  
Wang Xu ◽  
Yu-Peng Liu ◽  
...  
Keyword(s):  
Solid State ◽  
General Strategy ◽  
Two Photon ◽  
Full Color ◽  
Color Tunable

We report here a single-benzene based fluorescent framework, amino-terephthalonitrile, denoted SB-Fluor.

Full-color tunable organic nanoparticles with FRET-assisted enhanced two-photon excited fluorescence for bio-imaging

2013 ◽  
Vol 1 (44) ◽  
pp. 6035 ◽  
Author(s):  
Zhenzhen Xu ◽  
Qing Liao ◽  
Xingrui Shi ◽  
Hui Li ◽  
Haoli Zhang ◽  
...  
Keyword(s):  
Organic Nanoparticles ◽  
Two Photon ◽  
Full Color ◽  
Color Tunable ◽  
Bio Imaging

DNA Inspirited Rational Construction of Nonconventional Luminophores with Efficient and Color-Tunable Afterglow

2020 ◽  
Author(s):  
Yunzhong Wang ◽  
Saixing Tang ◽  
Yating Wen ◽  
Shuyuan Zheng ◽  
Bing Yang ◽  
...  
Keyword(s):  
Rational Design ◽  
Room Temperature ◽  
Double Helix ◽  
Mechanical Grinding ◽  
Room Temperature Phosphorescence ◽  
Color Tunable ◽  
Potential Applications ◽  
Rational Construction ◽  
Double Helix Structure ◽  
Made In

<div>Persistent room-temperature phosphorescence (p-RTP) from pure organics is attractive </div><div>due to its fundamental importance and potential applications in molecular imaging, </div><div>sensing, encryption, anticounterfeiting, etc.1-4 Recently, efforts have been also made in </div><div>obtaining color-tunable p-RTP in aromatic phosphors5 and nonconjugated polymers6,7. </div><div>The origin of color-tunable p-RTP and the rational design of such luminogens, </div><div>particularly those with explicit structure and molecular packing, remain challenging. </div><div>Noteworthily, nonconventional luminophores without significant conjugations generally </div><div>possess excitation-dependent photoluminescence (PL) because of the coexistence of </div><div>diverse clustered chromophores6,8, which strongly implicates the possibility to achieve </div><div>color-tunable p-RTP from their molecular crystals assisted by effective intermolecular </div><div>interactions. Here, inspirited by the highly stable double-helix structure and multiple </div><div>hydrogen bonds in DNA, we reported a series of nonconventional luminophores based on </div><div>hydantoin (HA), which demonstrate excitation-dependent PL and color-tunable p-RTP </div><div>from sky-blue to yellowish-green, accompanying unprecedentedly high PL and p-RTP </div><div>efficiencies of up to 87.5% and 21.8%, respectively. Meanwhile, the p-RTP emissions are </div><div>resistant to vigorous mechanical grinding, with lifetimes of up to 1.74 s. Such robust, </div><div>color-tunable and highly efficient p-RTP render the luminophores promising for varying </div><div>applications. These findings provide mechanism insights into the origin of color-tunable </div><div>p-RTP, and surely advance the exploitation of efficient nonconventional luminophores.</div>

scholarly journals Design, synthesis and application in biological imaging of a novel red fluorescent dye based on a rhodanine derivative

RSC Advances ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 160-163
Author(s):  
Zijing Li ◽  
Bin Huang ◽  
Yuan Wang ◽  
Wenbo Yuan ◽  
Yijing Wu ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Fluorescence Imaging ◽  
Inhibitory Concentration ◽  
Fluorescent Dye ◽  
Biological Imaging ◽  
Design Synthesis ◽  
Red Emission ◽  
Rhodanine Derivative

2RDNTPA can be applied in fluorescence imaging of living cancer cells (HepG2) with red emission of 620 nm and negligible cytotoxicity with a half maximal inhibitory concentration much more than 100 μM.

scholarly journals Biological nanoscale fluorescent probes: From structure and performance to bioimaging

2020 ◽  
Vol 39 (1) ◽  
pp. 209-221
Author(s):  
Jiafeng Wan ◽  
Xiaoyuan Zhang ◽  
Kai Zhang ◽  
Zhiqiang Su
Keyword(s):  
Fluorescent Probes ◽  
Organic Dyes ◽  
Resonance Energy Transfer ◽  
Resonance Energy ◽  
High Sensitivity ◽  
Biological Imaging ◽  
Fluorescent Materials ◽  
And Performance

Abstract In recent years, nanomaterials have attracted lots of attention from researchers due to their unique properties. Nanometer fluorescent materials, such as organic dyes, semiconductor quantum dots (QDs), metal nano-clusters (MNCs), carbon dots (CDs), etc., are widely used in biological imaging due to their high sensitivity, short response time, and excellent accuracy. Nanometer fluorescent probes can not only perform in vitro imaging of organisms but also achieve in vivo imaging. This provides medical staff with great convenience in cancer treatment. Combined with contemporary medical methods, faster and more effective treatment of cancer is achievable. This article explains the response mechanism of three-nanometer fluorescent probes: the principle of induced electron transfer (PET), the principle of fluorescence resonance energy transfer (FRET), and the principle of intramolecular charge transfer (ICT), showing the semiconductor QDs, precious MNCs, and CDs. The excellent performance of the three kinds of nano fluorescent materials in biological imaging is highlighted, and the application of these three kinds of nano fluorescent probes in targeted biological imaging is also introduced. Nanometer fluorescent materials will show their significance in the field of biomedicine.

Sign in / Sign up

Export Citation Format

Share Document