scholarly journals Multiple advanced logic gates made of DNA-Ag nanocluster and the application for intelligent detection of pathogenic bacterial genes

2018 ◽  
Vol 9 (7) ◽  
pp. 1774-1781 ◽  
Author(s):  
Xiaodong Lin ◽  
Yaqing Liu ◽  
Jiankang Deng ◽  
Yanlong Lyu ◽  
Pengcheng Qian ◽  
...  

A set of basic logic gates was constructed on a simple and universal DNA-AgNCs platform, and further integrated into advanced logic circuits for DNA computing and biosensing.

Author(s):  
А.А. Оленев ◽  
К.А. Киричек ◽  
Е.В. Потехина

В статье рассматриваются возможности применения библиотеки Logic системы компьютерной алгебры Maple в аспекте компьютерного моделирования логических схем в различных базисах. Смоделированы основные логические элементы в Maple. На конкретном примере детально представлен алгоритм построения логической схемы в различных базисах. The article discusses the possibilities of using the Logic library of the Maple computer algebra system in the aspect of computer modeling of logic circuits in various bases. Basic logic gates are modeled in Maple. On a specific example, an algorithm for constructing a logical circuit in various bases is presented in detail.


Molecules ◽  
2018 ◽  
Vol 23 (11) ◽  
pp. 2989 ◽  
Author(s):  
Weixuan Han ◽  
Changjun Zhou

DNA strand displacement, which plays a fundamental role in DNA computing, has been widely applied to many biological computing problems, including biological logic circuits. However, there are many biological cascade logic circuits with domain labels based on DNA strand displacement that have not yet been designed. Thus, in this paper, cascade 8-bit adder/subtractor with a domain label is designed based on DNA strand displacement; domain t and domain f represent signal 1 and signal 0, respectively, instead of domain t and domain f are applied to representing signal 1 and signal 0 respectively instead of high concentration and low concentration high concentration and low concentration. Basic logic gates, an amplification gate, a fan-out gate and a reporter gate are correspondingly reconstructed as domain label gates. The simulation results of Visual DSD show the feasibility and accuracy of the logic calculation model of the adder/subtractor designed in this paper. It is a useful exploration that may expand the application of the molecular logic circuit.


Molecules ◽  
2019 ◽  
Vol 24 (22) ◽  
pp. 4134 ◽  
Author(s):  
Fengjie Yang ◽  
Yuan Liu ◽  
Bin Wang ◽  
Changjun Zhou ◽  
Qiang Zhang

Recently, DNA molecules have been widely used to construct advanced logic devices due to their unique properties, such as a simple structure and predictable behavior. In fact, there are still many challenges in the process of building logic circuits. Among them, the scalability of the logic circuit and the elimination of the crosstalk of the cascade circuit have become the focus of research. Inspired by biological allosteric regulation, we developed a controllable molecular logic circuit strategy based on the activity of DNAzyme. The E6 DNAzyme sequence was temporarily blocked by hairpin DNA and activated under appropriate input trigger conditions. Using a substrate with ribonucleobase (rA) modification as the detection strand, a series of binary basic logic gates (YES, AND, and INHIBIT) were implemented on the computational component platform. At the same time, we demonstrate a parallel demultiplexer and two multi-level cascade circuits (YES-YES and YES-Three input AND (YES-TAND)). In addition, the leakage of the cascade process was reduced by exploring factors such as concentration and DNA structure. The proposed DNAzyme activity regulation strategy provides great potential for the expansion of logic circuits in the future.


2003 ◽  
Vol 26 (2) ◽  
pp. 111-114 ◽  
Author(s):  
Muhammad Taher Abuelma'atti

In this letter a new technique is introduced for implementing the basic logic functions using analog current-mode techniques. By expanding the logic functions in power series expressions, and using summers and multipliers, realization of the basic logic functions is simplified. Since no transistors are working in saturation, the problem of fan-out is alleviated. To illustrate the proposed technique, a circuit for simultaneous realization of the logic functions NOT, OR, NAND and XOR is considered. SPICE simulation results, obtained with 3 V supply, are included


Author(s):  
Narciso Garcia ◽  
Arthur Damask ◽  
Steven Schwarz
Keyword(s):  

2018 ◽  
Vol 42 (22) ◽  
pp. 18050-18058 ◽  
Author(s):  
Juan D. Villada ◽  
Richard F. D’Vries ◽  
Mario Macías ◽  
Fabio Zuluaga ◽  
Manuel N. Chaur

A new polymorph of fluorescein hydrazone was fully characterized via single X-ray crystallography. In addition, multiple logic circuits and a Half-Adder operator were designed using the fluorescence and UV-Vis switching responses of the fluorescein compound to different metal cations and pH changes.


Sign in / Sign up

Export Citation Format

Share Document