scholarly journals Self-quenched ferrocenyl diketopyrrolopyrrole organic nanoparticles with amplifying photothermal effect for cancer therapy

2017 ◽  
Vol 8 (11) ◽  
pp. 7457-7463 ◽  
Author(s):  
Pingping Liang ◽  
Qianyun Tang ◽  
Yu Cai ◽  
Gongyuan Liu ◽  
Weili Si ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Photothermal Therapy ◽  
Photoacoustic Imaging ◽  
Photothermal Effect ◽  
Organic Nanoparticles

A NIR D–A–D structure of a ferrocene flanked diketopyrrolopyrrole derivative with a tetracyanobutadiene unit is synthesized for photoacoustic imaging-guided amplifying photothermal therapy.

scholarly journals Boosting Chemodynamic Therapy by the Synergistic Effect of Co-Catalyze and Photothermal Effect Triggered by the Second Near-Infrared Light

2020 ◽  
Vol 12 (1) ◽  
Author(s):  
Songtao Zhang ◽  
Longhai Jin ◽  
Jianhua Liu ◽  
Yang Liu ◽  
Tianqi Zhang ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Bovine Serum Albumin ◽  
Synergistic Effect ◽  
Bovine Serum ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Infrared Light ◽  
Photothermal Effect ◽  
Reaction Efficiency

AbstractIn spite of the tumor microenvironments responsive cancer therapy based on Fenton reaction (i.e., chemodynamic therapy, CDT) has been attracted more attentions in recent years, the limited Fenton reaction efficiency is the important obstacle to further application in clinic. Herein, we synthesized novel FeO/MoS2 nanocomposites modified by bovine serum albumin (FeO/MoS2-BSA) with boosted Fenton reaction efficiency by the synergistic effect of co-catalyze and photothermal effect of MoS2 nanosheets triggered by the second near-infrared (NIR II) light. In the tumor microenvironments, the MoS2 nanosheets not only can accelerate the conversion of Fe3+ ions to Fe2+ ions by Mo4+ ions on their surface to improve Fenton reaction efficiency, but also endow FeO/MoS2-BSA with good photothermal performances for photothermal-enhanced CDT and photothermal therapy (PTT). Consequently, benefiting from the synergetic-enhanced CDT/PTT, the tumors are eradicated completely in vivo. This work provides innovative synergistic strategy for constructing nanocomposites for highly efficient CDT.

Organic molecules with propeller structures for efficient photoacoustic imaging and photothermal ablation of cancer cells

2017 ◽  
Vol 1 (8) ◽  
pp. 1556-1562 ◽  
Author(s):  
Xiaolei Cai ◽  
Jie Liu ◽  
Weng Heng Liew ◽  
Yukun Duan ◽  
Junlong Geng ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Small Molecule ◽  
Photothermal Therapy ◽  
Organic Molecules ◽  
Photoacoustic Imaging ◽  
Organic Nanoparticles ◽  
Photothermal Ablation ◽  
Donor Acceptor

We report organic nanoparticles for efficient photoacoustic imaging and photothermal therapy, based on the small molecule BTPETTQ which has a propeller structure and a donor–acceptor–donor configuration.

A polydopamine-coated LAPONITE®-stabilized iron oxide nanoplatform for targeted multimodal imaging-guided photothermal cancer therapy

2019 ◽  
Vol 7 (24) ◽  
pp. 3856-3864 ◽  
Author(s):  
Mengxue Liu ◽  
Jiulong Zhang ◽  
Xin Li ◽  
Chao Cai ◽  
Xueyan Cao ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Sialic Acid ◽  
Magnetic Resonance ◽  
Cancer Therapy ◽  
Cancer Cells ◽  
Photothermal Therapy ◽  
Multimodal Imaging ◽  
Photoacoustic Imaging

A novel targeted theranostic nanoplatform (LAP–Fe3O4@PDA–PEG–PBA) is constructed for magnetic resonance and photoacoustic imaging-guided photothermal therapy of cancer cells overexpressing sialic acid.

scholarly journals Enzyme-Loaded pH-Sensitive Photothermal Hydrogels for Mild-temperature-mediated Combinational Cancer Therapy

2021 ◽  
Vol 9 ◽  
Author(s):  
Jindong Xia ◽  
Xueqin Qing ◽  
Junjian Shen ◽  
Mengbin Ding ◽  
Yue Wang ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Ph Sensitive ◽  
Photothermal Effect ◽  
Photothermal Conversion ◽  
Normal Tissues ◽  
Turn On ◽  
Shock Proteins ◽  
Mild Temperature

Photothermal therapy (PTT) that utilizes hyperthermia to ablate cancer cells is a promising approach for cancer therapy, while the generated high temperature may lead to damage of surrounding normal tissues and inflammation. We herein report the construction of glucose oxidase (GOx)-loaded hydrogels with a pH-sensitive photothermal conversion property for combinational cancer therapy at mild-temperature. The hydrogels (defined as CAG) were formed via coordination of alginate solution containing pH-sensitive charge-transfer nanoparticles (CTNs) as the second near-infrared (NIR-II) photothermal agents and GOx. In the tumor sites, GOx was gradually released from CAG to consume glucose for tumor starvation and aggravate acidity in tumor microenvironment that could turn on the NIR-II photothermal conversion property of CTNs. Meanwhile, the released GOx could suppress the expression of heat shock proteins to enable mild NIR-II PTT under 1,064 nm laser irradiation. As such, CAG mediated a combinational action of mild NIR-II PTT and starvation therapy, not only greatly inhibiting the growth of subcutaneously implanted tumors in a breast cancer murine model, but also completely preventing lung metastasis. This study thus provides an enzyme loaded hydrogel platform with a pH-sensitive photothermal effect for mild-temperature-mediated combinational cancer therapy.

Hybrid MoSe2–indocyanine green nanosheets as a highly efficient phototheranostic agent for photoacoustic imaging guided photothermal cancer therapy

2018 ◽  
Vol 6 (6) ◽  
pp. 1503-1516 ◽  
Author(s):  
Jingqin Chen ◽  
Xueshen Li ◽  
Xiaoyang Liu ◽  
Huixiang Yan ◽  
Zhihua Xie ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Indocyanine Green ◽  
Photothermal Therapy ◽  
Photoacoustic Imaging ◽  
Highly Efficient

The synthesis of sMoSe2–ICG NSs for highly efficient tumor photoacoustic imaging guided photothermal therapy.

Near-infrared conjugated polymers for photoacoustic imaging-guided photothermal/chemo combination therapy

2017 ◽  
Vol 5 (27) ◽  
pp. 5479-5487 ◽  
Author(s):  
Yue Cao ◽  
Yannan Wu ◽  
Guannan Wang ◽  
Jingwen Yi ◽  
Chunlei Yu ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Combination Therapy ◽  
Conjugated Polymers ◽  
Conversion Efficiency ◽  
Infrared Absorption ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Photoacoustic Imaging ◽  
Imaging Agents ◽  
New Generation

Conjugated polymers with intensive near-infrared absorption and high photothermal conversion efficiency have emerged as a new generation of photothermal therapy and photoacoustic imaging agents for cancer therapy.

Silicon nanowires decorated with gold nanoparticles via in situ reduction for photoacoustic imaging-guided photothermal cancer therapy

2019 ◽  
Vol 7 (28) ◽  
pp. 4393-4401 ◽  
Author(s):  
Lina Sun ◽  
Ying Chen ◽  
Fei Gong ◽  
Qian Dang ◽  
Guangzhen Xiang ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Cancer Therapy ◽  
Solid Tumors ◽  
Silicon Nanowires ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Photoacoustic Imaging ◽  
In Situ Reduction ◽  
Great Progress

Photothermal therapy (PTT) in the first near-infrared (NIR-I) window has made great progress in the treatment of solid tumors, while only a few PTT agents in the second NIR (NIR-II) region have been studied.

2-Dicyanomethylenethiazole based NIR absorbing organic nanoparticles for photothermal therapy and photoacoustic imaging

2019 ◽  
Vol 7 (25) ◽  
pp. 3950-3957 ◽  
Author(s):  
Zikang Chen ◽  
Qi Xia ◽  
Yuping Zhou ◽  
Xipan Li ◽  
Li Qi ◽  
...  
Keyword(s):  
Conversion Efficiency ◽  
Photothermal Therapy ◽  
Photoacoustic Imaging ◽  
Organic Nanoparticles ◽  
Photothermal Conversion ◽  
Nir Absorption ◽  
Good Biocompatibility

TPTHM NPs are candidates for PAI/PTT agents due to their NIR absorption, good biocompatibility, high photostability and photothermal conversion efficiency (38%).

Bi19S27I3 nanorods: a new candidate for photothermal therapy in the first and second biological near-infrared windows

Nanoscale ◽  
2021 ◽  
Author(s):  
Jinsong Xiong ◽  
Qinghuan Bian ◽  
Shuijin Lei ◽  
Yatian Deng ◽  
Kehan Zhao ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Research Interest ◽  
The Past ◽  
Nir Light ◽  
Considerable Research ◽  
Key Factor

Near-infrared (NIR) light induced photothermal cancer therapy using nanomaterials as photothermal agents has attracted considerable research interest over the past few years. As the key factor in the photothermal therapy...

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