scholarly journals Facile production of nanocomposites of carbon nanotubes and polycaprolactone with high aspect ratios with potential applications in drug delivery

RSC Advances ◽  
2018 ◽  
Vol 8 (30) ◽  
pp. 16444-16454 ◽  
Author(s):  
Edyta Niezabitowska ◽  
Jessica Smith ◽  
Mark R. Prestly ◽  
Riaz Akhtar ◽  
Felix W. von Aulock ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Drug Delivery ◽  
Carbon Nanotube ◽  
Aspect Ratios ◽  
Potential Applications ◽  
Facile Route

Facile route to polymer carbon nanotube nanocomposites.

Nanohybrid Nanoparticles Based on Chitosan/Functionalized Carbon Nanotubes as Anti-HIV Nanocarrier

NANO ◽  
2015 ◽  
Vol 10 (01) ◽  
pp. 1550010 ◽  
Author(s):  
R. Afshari ◽  
S. Mazinani ◽  
M. Abdouss
Keyword(s):  
Carbon Nanotubes ◽  
Drug Delivery ◽  
Carbon Nanotube ◽  
Drug Delivery Systems ◽  
Drug Loading ◽  
Delivery Systems ◽  
Potential Applications ◽  
Multi Walled Carbon Nanotubes ◽  
Walled Carbon Nanotubes

Carbon nanotube-natural biopolymer nanovectors have important potential applications in delivery system for drugs and biomolecules. In this work, the use of multi-walled carbon nanotubes (MWCNT) as nanoreservoirs for drug loading and controlled release is demonstrated. We synthesized different carbon nanotube-based drug delivery systems including acid and amide-functionalized MWCNT; chitosan (CS) covalently grafted to functionalized MWCNT and MWCNT-CS nanoparticles (NPs) using an ionotropic gelation method as a sustained-release systems for delivery of Tenofovir (hydrophilic anti-retroviral drug). The prepared NPs as different drug delivery systems were characterized by Fourier transform infrared (FTIR) spectroscopy, thermogravimetric analysis (TGA) and scanning electron microscopy (SEM). As it is shown, in vitro drug release studies indicated that the cumulative release rate of Tenofovir from MWCNT–CS NPs shows the best result and it reaches the maximum value (90%) after about 120 h. Moreover, comparing to ungrafted CNTs, MWCNT–CS shows high dispersability and long-term stability in aqueous medium which approves the effective solubilization of MWCNT followed by grafting with CS.

Adsorption of Fluoride by Aligned Carbon Nanotubes Supported Ceria Nanoparticles

2007 ◽  
Vol 121-123 ◽  
pp. 1221-1224 ◽  
Author(s):  
Ze Chao Di ◽  
Yan Hui Li ◽  
Xian Jia Peng ◽  
Zhao Kun Luan ◽  
Ji Liang
Keyword(s):  
Heat Treatment ◽  
Carbon Nanotubes ◽  
Drinking Water ◽  
Carbon Nanotube ◽  
Fluoride Concentration ◽  
Ceria Nanoparticles ◽  
Adsorption Effect ◽  
Fluoride Adsorption ◽  
Aligned Carbon Nanotubes ◽  
Potential Applications

Ceria nanoparticles supported on aligned carbon nanotubes (CeO2/ACNTs), a novel adsorbent for fluoride from drinking water, were prepared by chemical reaction of CeCl3 with NaOH on aligned carbon nanotube solution and subsequent heat treatment. The best fluoride adsorption effect of CeO2/ACNTs occurs at pH 4.0 ~ 9.0. The largest adsorption capacity of CeO2/ACNTs reaches 33.7 mg g-1 at an equilibrium fluoride concentration of 18.0 mg l-1 at pH 7.0. The experiment results suggest that CeO2/ACNTs have great potential applications in environmental protection.

scholarly journals Self-assembled nanocapsules in water: a molecular mechanistic study

2017 ◽  
Vol 19 (31) ◽  
pp. 20377-20382
Author(s):  
Hang Xiao ◽  
Xiaoyang Shi ◽  
Xi Chen
Keyword(s):  
Carbon Nanotubes ◽  
Drug Delivery ◽  
Internal Pressure ◽  
Mechanistic Study ◽  
Potential Applications ◽  
Self Assembled ◽  
High Internal Pressure ◽  
Very High

One-end-open carbon nanotubes with an appropriate radius difference can coaxially self-assemble into a nanocapsule with very high internal pressure (on the order of 1 GPa), underpinning potential applications in nano-reactors, drug-delivery, etc.

The “click-on-tube” approach for the production of efficient drug carriers based on oxidized multi-walled carbon nanotubes

2016 ◽  
Vol 4 (21) ◽  
pp. 3823-3831 ◽  
Author(s):  
Stefano Fedeli ◽  
Alberto Brandi ◽  
Lorenzo Venturini ◽  
Paola Chiarugi ◽  
Elisa Giannoni ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Drug Delivery ◽  
Carbon Nanotube ◽  
Drug Delivery System ◽  
Delivery System ◽  
Drug Carriers ◽  
Multi Walled Carbon Nanotube ◽  
Multi Walled Carbon Nanotubes ◽  
Walled Carbon Nanotubes ◽  
Straightforward Approach

An efficient drug delivery system through a straightforward approach to multi-walled carbon nanotube decoration.

scholarly journals Carbon-nanotube-based electrically-short resonant antennas

2013 ◽  
Vol 6 (1) ◽  
pp. 57-62
Author(s):  
Pierre Franck ◽  
Dominique Baillargeat ◽  
Beng Kang Tay
Keyword(s):  
Carbon Nanotubes ◽  
Carbon Nanotube ◽  
Physical Interpretation ◽  
Trend Prediction ◽  
Trade Offs ◽  
Monopole Antennas ◽  
Potential Applications ◽  
Rf Devices

We present a study on using carbon nanotubes (CNTs) as the radiating part of resonant antennas in order to reduce their dimensions. A mesoscopic electromagnetic (EM) model for CNTs was developed to allow the simulation of RF devices in classical EM solvers while retaining the specific properties of CNTs. A circuit approach is also used to provide a physical interpretation of the results on monopole antennas and trend prediction. These techniques constitute a platform to study the trends and trade-offs involved in the design of these antennas. Finally, these results are used to assess suitable fabrication techniques for CNT-based short resonant antennas and conclusions are drawn on their potential applications.

scholarly journals Carboxylated Capped Carbon Nanotubes Interacting with Nimesulide Molecules: Applied Electric Fields Effects

2015 ◽  
Vol 2015 ◽  
pp. 1-6
Author(s):  
Vivian Machado de Menezes ◽  
Ivana Zanella ◽  
Solange Binotto Fagan
Keyword(s):  
Carbon Nanotubes ◽  
Drug Delivery ◽  
Carbon Nanotube ◽  
Ab Initio ◽  
Electric Fields ◽  
Carboxyl Group ◽  
External Electric Fields ◽  
Drug Delivery Applications ◽  
Repulsive Forces

Interactions of carboxylated capped carbon nanotubes with nimesulide molecules under electric fields were investigated byab initiosimulations. Repulsive forces between the nimesulide molecules and the carboxyl group of the carbon nanotubes, except for the nimesulide radical configuration, were observed. To keep the original molecule in the pristine form, electric fields with different intensities were applied, where changes in the behavior of the interactions between the molecules were noticed. It was shown that the intensity of the interaction between the nimesulide and the hydrophilic carboxylated capped carbon nanotube can be modulated by the action of the external electric fields making promising systems for drug delivery applications.

scholarly journals Carbon Nanotube and Graphene Based Polyamide Electrospun Nanocomposites: A Review

2016 ◽  
Vol 2016 ◽  
pp. 1-16 ◽  
Author(s):  
Fabiola Navarro-Pardo ◽  
Ana L. Martinez-Hernandez ◽  
Carlos Velasco-Santos
Keyword(s):  
Mechanical Properties ◽  
Carbon Nanotubes ◽  
Carbon Nanotube ◽  
Research Groups ◽  
Potential Applications ◽  
Versatile Technique

Electrospinning is a unique and versatile technique to produce nanofibres; the facility to incorporate fillers has expanded its range of applications. This review gives a brief description of the process and the different polymers employed for obtaining nanofibres. Owing to the ability of fibrillation of polyamides, these polymers have resulted in a wide variety of interesting results obtained when using this technique; therefore these features are summarised. Additionally, because of the feasibility of incorporating carbon nanotubes and graphene in these nanofibres and the growing interest on these nanomaterials, this review focuses in the most common methods employed for their incorporation in electrospun polyamides. Several equipment setups used for the electrospinning of the nanofibres are explained. The outstanding electrical, optical, crystallinity, and mechanical properties obtained by a number of research groups are discussed. The potential applications of the resulting nanocomposites have also been explored.

scholarly journals Carbon and Core Shell like Molecular Nanostructures in Cancer diagnosis and Therapy

2018 ◽  
Vol 2 (1) ◽  
Keyword(s):  
Carbon Nanotubes ◽  
Drug Delivery ◽  
Biomedical Applications ◽  
Single Walled Carbon Nanotubes ◽  
Pristine Cnts ◽  
Potential Applications ◽  
Real Time Applications ◽  
Cancer Diagnosis And Therapy ◽  
Walled Carbon Nanotubes ◽  
Cancerous Cells

During the past years, carbon nanotubes (CNTs) have attracted considerable interest since their first discovery. Great progress has been made in the field of nanomaterials given their great potential in biomedical applications. Carbon nanotubes (CNTs), due to their unique physicochemical properties, have become a popular tool in cancer diagnosis and therapy. They are considered one of the most promising nanomaterials with the capability of both detecting the cancerous cells and delivering drugs or small therapeutic molecules to these cells because of the unique structure, extremely high specific surface area to-volume ratio enable them to use in an intense real time applications such as detection and treatment of cancerous cells, nervous disorders, tissue repair. and excellent electrical and mechanical properties carbon nanotubes composed of excellent mechanical strength, electrical and thermal conductivities makes them a suitable substance toward developing medical devices., CNTs have been explored in almost every single cancer treatment modality, including drug delivery with small nanomolecules, lymphatic targeted chemotherapy, thermal therapy, photodynamic therapy, and gene therapy and demonstrate a great promise in their use in targeted drug delivery systems, diagnostic techniques and in bio-analytical applications. Majority of the biomedical applications of CNTs must be used after successful functionalization for more potential applications than pristine CNTs. There are several approaches to modify pristine CNTs to potentially active. CNTs poised into the human life and exploited in medical context. Here in, we reviewed the following topics (i) Functionalization of CNTs (ii) CNTs in real time applications such as drug delivery, gene therapy, biosensors and bio imaging; (iii) CNTs 3D printed scaffolds for medicine and (iv) Biocompatability and Biodegradability. Single-walled carbon nanotubes (SWCNTs) were synthesized using the high-pressure carbon monoxide disproportionation process (HiPCO). The SWCNT diameter, diameter distribution and yield can be varied depending on the process parameters. The obtained HiPCO product present an iron nanoparticle encapsulated heteronanocarbon (core-shell nanoparticles) at low pressure (1 bar) after removing of iron metal catalyst nanoparticle and amorphous carbon by acid immersion and oxidation. The resulting therapeutic molecule in the form of coreshell nanoparticles and single walled carbon nanotubes after functionalization by filling of iron can be use as therapeutic nanomaterials in nanomedicine in diagnosis and treatment of cancer tumor. This paper describes the synthesis method and role of multifunctional nanoparticle in diagnosis and treatment of cancer. Therefore, the aim of this review is to provide basic information on nanoparticles, describe previously developed methods to functionalize nanoparticles and discuss their potential applications in nanobiomedical and mention the therapeutic nanoparticle large scale production and commercialization challenges. In the final part of the review, emphasis is given on the pharmacokinetic aspects of carbon nanotubes including administration routes, absorption mechanisms, distribution and elimination of carbon nanotubes based systems. Lastly, a comprehensive account about the potential biomedical applications has been given followed by insights into the future carbon nanotubes from synthesis to in vivo biomedical applications.

Bioinspired Graphene Nanogut

2013 ◽  
Vol 80 (6) ◽  
Author(s):  
Zhao Qin ◽  
Markus J. Buehler
Keyword(s):  
Carbon Nanotubes ◽  
Drug Delivery ◽  
Carbon Nanotube ◽  
Biological System ◽  
Scaling Laws ◽  
Functional Materials ◽  
Cross Sectional ◽  
Mismatch Strain ◽  
Damage Repair ◽  
Low Dimensional

Low-dimensional nanomaterials are attractive for various applications, including damage repair, drug delivery, and bioimaging. The ability to control the morphology of nanomaterials is critical for manufacturing as well as for utilizing them as functional materials or devices. However, the manipulation of such materials remains challenging, and effective methods to control their morphology remain limited. Here, we propose to mimic a macroscopic biological system—the gut—as a means to control the nanoscale morphology by exploiting the concept of mismatch strain. We show that, by mimicking the development of the gut, one can obtain a controlled wavy shape of a combined carbon nanotube and graphene system. We show that the scaling laws that control the formation of the gut at the macroscale are suitable for ultrasmall-diameter carbon nanotubes with a diameter smaller than 7 Å but do not account for the morphology of systems with larger diameter nanotubes. We find that the deviation is caused by cross-sectional buckling of carbon nanotube, where this behavior relates to the different constitutive laws for carbon nanotube and graphene in contrast to the macroscale biological system. Our study illustrates the possibility of downscaling macroscale phenomena to the nanoscale using continuum mechanics theory, with wide-ranging applications in nanotechnology.

On the Modeling of Carbon Nanotubes as Drug Delivery Nanocapsules

2012 ◽  
pp. 222-234
Author(s):  
F. Alisafaei ◽  
R. Ansari
Keyword(s):  
Carbon Nanotubes ◽  
Drug Delivery ◽  
Carbon Nanotube ◽  
Van Der Waals ◽  
Single Walled Carbon Nanotubes ◽  
Medical Applications ◽  
Suction Force ◽  
Nanoscale Object ◽  
Or Genes ◽  
Walled Carbon Nanotubes

The structure of carbon nanotubes is recognized to be suitable for medical applications such as encapsulating drugs or genes with the aim of targeted deliveries. In this regard, knowing about the suction force exerted on a nonoscale object which is supposed to be sucked into a carbon nanotube, and whether the object is accepted by the carbon nanotube are important issues to be studied. In this chapter, considering the nanoscale object as a carbon nanotube, a new semi-analytical method is developed to determine the van der Waals interaction between two concentric single-walled carbon nanotubes.

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