scholarly journals A feasible strategy for self-assembly of gold nanoparticlesviadithiol-PEG for photothermal therapy of cancers

RSC Advances ◽  
2018 ◽  
Vol 8 (11) ◽  
pp. 6120-6124 ◽  
Author(s):  
Yingjie Fu ◽  
Qishuai Feng ◽  
Yajing Shen ◽  
Mengwei Chen ◽  
Chang Xu ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Polyethylene Glycol ◽  
Self Assembly ◽  
Photothermal Therapy ◽  
Cross Linking ◽  
Self Assembled

We designed and explored self-assembled gold nanoparticles (SAGNPs) by introducing dithiol modified polyethylene glycol (PEG) for internanoparticle cross-linking.

Self-assembly of gold nanoparticles in a block copolymer aggregate template driven by hydrophobic interactions

2019 ◽  
Vol 10 (46) ◽  
pp. 6269-6277
Author(s):  
Jong Dae Jang ◽  
Sang-Woo Jeon ◽  
Young-Jin Yoon ◽  
Joona Bang ◽  
Young Soo Han ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Block Copolymer ◽  
Self Assembly ◽  
Hydrophobic Interactions ◽  
Self Assembled

We report various self-assembled structures of gold nanoparticles in a block copolymer aggregate template, which are easily driven by hydrophobic interactions.

scholarly journals Self-Assembly of Semiconducting-Plasmonic Gold Nanoparticles with Enhanced Optical Property for Photoacoustic Imaging and Photothermal Therapy

Theranostics ◽  
2017 ◽  
Vol 7 (8) ◽  
pp. 2177-2185 ◽  
Author(s):  
Zhen Yang ◽  
Jibin Song ◽  
Yunlu Dai ◽  
Jingyi Chen ◽  
Feng Wang ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Optical Property ◽  
Self Assembly ◽  
Photothermal Therapy ◽  
Photoacoustic Imaging

Enzyme-triggered self-assembly of gold nanoparticles for enhanced retention effects and photothermal therapy of prostate cancer

2018 ◽  
Vol 54 (70) ◽  
pp. 9841-9844 ◽  
Author(s):  
Shuyan Yang ◽  
Defan Yao ◽  
Yanshu Wang ◽  
Weitao Yang ◽  
Bingbo Zhang ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Gold Nanoparticles ◽  
Targeted Therapy ◽  
Gold Nanoparticle ◽  
Self Assembly ◽  
Photothermal Therapy

A peptide-modified gold nanoparticle was developed for tumour-targeted therapy.

Electrochemical Aptasensor for Label-Free Detection of Protein Based on Gold Nanoparticle Involved Self-Assembly

2013 ◽  
Vol 310 ◽  
pp. 177-182
Author(s):  
Song Bai Zhang ◽  
Bing Jun Zhang ◽  
Qian Liu ◽  
Xia Hu ◽  
Li Ying Zheng ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Gold Nanoparticle ◽  
Self Assembly ◽  
Gold Electrode ◽  
Hot Water ◽  
Target Protein ◽  
Capture Probe ◽  
Label Free ◽  
Label Free Detection ◽  
Self Assembled

A label-free electrochemical biosensing strategy based on gold nanoparticle involved layer-by-layer self assembly for the detection of protein is proposed using platelet derived growth factor-BB dimer (PDGF-BB) as the model analyte. Utilizing the strong sulfur-Au affinity, ethanthiol and capture probe modified gold nanoparticles are self-assembled onto the surface of gold electrode successively. The aptamer probe for target protein hybridizes with the capture probe and the biosensor is fabricated. By measuring ac current voltammetry, the target protein can be sensitively detected in a linear dynamic range from 1-1000 ng/mL with a low detection limit of 0.5 ng/mL. Making use of self-assembled gold nanoparticles layer, a large amount of capture probes can be modified onto the gold electrode, supporting the high sensitivity of the proposed strategy. In addition, good reproducibility, high selectivity and stability are achieved. In particular, the biosensor can be easily regenerated by melting in hot water, making it reusable.

Interface-Directed Self-Assembly of Gold Nanoparticles and Fabrication of Hybrid Hollow Capsules by Interfacial Cross-Linking Polymerization

Langmuir ◽  
2012 ◽  
Vol 28 (25) ◽  
pp. 9365-9371 ◽  
Author(s):  
Jia Tian ◽  
Liang Yuan ◽  
Mingming Zhang ◽  
Fan Zheng ◽  
Qingqing Xiong ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Self Assembly ◽  
Cross Linking

scholarly journals Noncovalent Interaction between Gold Nanoparticles and Multiwalled Carbon Nanotubes via an Intermediatory

2009 ◽  
Vol 2009 ◽  
pp. 1-7 ◽  
Author(s):  
Jui-Ming Yeh ◽  
Kuan-Yeh Huang ◽  
Su-Yin Lin ◽  
Yu-Yao Wu ◽  
Chao-Chen Huang ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Gold Nanoparticles ◽  
Self Assembly ◽  
Thiol Group ◽  
Noncovalent Interaction ◽  
Multiwalled Carbon ◽  
Au Nps ◽  
Multi Walled Carbon Nanotubes ◽  
Self Assembled ◽  
Reflectance Ftir

A new and effective method has been developed where self-assembled gold nanoparticles (Au-NPs) of ∼10 nm diameter are successfully attached onto the surface of sidewalls and ends of thiol-terminated multi-walled carbon nanotubes (MWNTs) functionalized with orthomercaptoaniline, acting as a bridging agent. It can bridge the carbon nanotubes (CNTs) and Au-NPs via the bi-functional moiety with benzene unit at one end and thiol group at the other end by self-assembly. Theortho-mercaptoaniline was first grafted onto the surface of the CNTs viaπ-πinteraction between the benzene ring of the mercaptoaniline andπ-conjugated body of MWNTs surface to produce thiol-terminated CNTs. The bare surface of Au-NPs facilitates to attach on the thiol group of the thiol-terminated CNTs. Attenuated total reflectance FTIR, UV-visible, Raman spectroscopy and X-ray powder diffraction studies were used to verify whether the mercapto-benzene moieties have been attached to theπ-conjugated body of functionalized MWNTs. The direct evidence is obtained from transmission electron microscope (TEM) images where self-assembled Au-NPs are attached onto the functionalized MWNTs.

scholarly journals Selective Detection of Human Lung Adenocarcinoma Cells Based on the Aptamer-Conjugated Self-Assembled Monolayer of Gold Nanoparticles

Micromachines ◽  
2019 ◽  
Vol 10 (3) ◽  
pp. 195 ◽  
Author(s):  
Ngoc-Viet Nguyen ◽  
Chun-Ping Jen
Keyword(s):  
Gold Nanoparticles ◽  
Self Assembly ◽  
Human Lung ◽  
Specific Binding ◽  
Physical And Mechanical Properties ◽  
Target Cells ◽  
Self Assembled Monolayer ◽  
Assembly Method ◽  
Human Lung Adenocarcinoma Cells ◽  
Self Assembled

This study established a microfluidic chip for the capture of A549 human lung circulating tumor cells via the aptamer-conjugated self-assembled monolayer (SAM) of gold nanoparticles (AuNPs) in the channel. AuNPs are among the most attractive nanomaterials for the signal enhancement of biosensors owing to their unique chemical, physical, and mechanical properties. The microchip was fabricated using soft photolithography and casting and molding techniques. A self-assembly method was designed to attach AuNPs, cell-specific aptamers, and target cells onto the desired area (i.e., SAM area). In this study, the gold microelectrode configuration was characterized by fluorescence microscopy and impedance measurements to confirm the important modification steps. Subsequently, several investigations with the proposed assay were conducted with different cell samples to determine the specific binding ability of the device for A549 adenocarcinoma cancer cells. This work has ensured a simple, convenient, selective, and sensitive approach for the development of biosensors for lung cancer detection during the early stages.

scholarly journals Self-assembly of gold supraparticles with crystallographically aligned and strongly coupled nanoparticle building blocks for SERS and photothermal therapy

2016 ◽  
Vol 7 (9) ◽  
pp. 6232-6237 ◽  
Author(s):  
S. Paterson ◽  
S. A. Thompson ◽  
J. Gracie ◽  
A. W. Wark ◽  
R. de la Rica
Keyword(s):  
Gold Nanoparticles ◽  
Self Assembly ◽  
Photothermal Therapy ◽  
Building Blocks ◽  
New Method ◽  
Strongly Coupled ◽  
Self Assembling

A new method is introduced for self-assembling citrate-capped gold nanoparticles into supraparticles with crystallographically aligned building blocks.

Self-assembled targeted folate-conjugated eight-arm-polyethylene glycol–betulinic acid nanoparticles for co-delivery of anticancer drugs

2015 ◽  
Vol 3 (18) ◽  
pp. 3754-3766 ◽  
Author(s):  
Lin Dai ◽  
Xin Cao ◽  
Ke-Feng Liu ◽  
Chun-Xiao Li ◽  
Gui-Feng Zhang ◽  
...  
Keyword(s):  
Polyethylene Glycol ◽  
Cancer Cells ◽  
Solid Tumors ◽  
Anticancer Drugs ◽  
Betulinic Acid ◽  
Self Assembly ◽  
Assembly Process ◽  
Epr Effect ◽  
Self Assembled

Folate-8arm-PEG–betulinic acid nanoparticles prepared via a self-assembly process are stable in circulation, resulting in the EPR effect of solid tumors, and are efficiently internalized by cancer cells.

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