scholarly journals Construction of a quaternary ammonium salt platform with different alkyl groups for antibacterial and biosensor applications

RSC Advances ◽  
2018 ◽  
Vol 8 (6) ◽  
pp. 2941-2949 ◽  
Author(s):  
Xue Lv ◽  
Chuang Liu ◽  
Shixin Song ◽  
Yun Qiao ◽  
Yuanjiao Hu ◽  
...  
Keyword(s):  
Catalytic Activity ◽  
Chain Length ◽  
Ammonium Salt ◽  
Quaternary Ammonium ◽  
Quaternary Ammonium Salt ◽  
Alkyl Chain ◽  
Antibacterial Activities ◽  
Alkyl Chain Length ◽  
Alkyl Groups ◽  
Biosensor Applications

The immobilized-protein in an appropriate alkyl chain length of DM displayed higher antibacterial activities, exhibited a more effective DET and a promising catalytic activity toward H2O2.

scholarly journals Gemini (dimeric) surfactant perturbation of the human erythrocyte.

2000 ◽  
Vol 47 (3) ◽  
pp. 651-660 ◽  
Author(s):  
M Dubnicková ◽  
M Bobrowska-Hägerstrand ◽  
T Söderström ◽  
A Iglic ◽  
H Hägerstrand
Keyword(s):  
Cell Surface ◽  
Chain Length ◽  
Human Erythrocyte ◽  
Alkyl Chain ◽  
Alkyl Chain Length ◽  
Single Chain ◽  
Inner Membrane ◽  
Phosphatidylserine Exposure ◽  
Alkyl Groups ◽  
Dimeric Surfactant

We studied the ability of di-cationic gemini surfactantsdi (amphiphiles), i.e. 1,4-butanediammonium-N,N-dialkyl-N,N,N',N'-tetramethyl bromides (Di-Cm-di-QAS (s = 4), where m = 8, 11, 13, 16 and s = the number of alkyl groups in the spacer) to induce shape alteration, vesiculation, haemolysis and phosphatidylserine exposure in human erythrocytes, and to protect erythrocytes against hypotonic haemolysis. At high sublytic concentrations the Di-Cm-di-QAS (s = 4) amphiphiles rapidly induced echinocytic (spiculated) shapes and a release of exovesicles, mainly in the form of tubes, from the cell surface. Following 60 min incubation erythrocytes were sphero-echinocytic and a few cells with invaginations/endovesicles were observed. No phosphatidylserine exposure was detected. The haemolytic potency increased with an increase of the alkyl chain length. At sublytic concentrations the Di-Cm-di-QAS (s = 4) amphiphiles protected erythrocytes against hypotonic haemolysis. It is suggested that the Di-Cm-di-QAS (s = 4) amphiphiles perturb the membrane in a similar way as single-chain cationic amphiphiles, but that they do not easily translocate to the inner membrane leaflet.

Poly(n-alkylsilsesquioxane) liquids prepared by cosolvent-free hydrolytic polycondensation of n-alkyltrialkoxysilanes: effects of liquid–liquid phase separation during aging and alkyl chain length on structure and viscosity

2016 ◽  
Vol 45 (39) ◽  
pp. 15532-15540 ◽  
Author(s):  
Yuko Fukuda ◽  
Koichi Kajihara ◽  
Shiori Kakinoki ◽  
Junhyeok Jang ◽  
Hirohisa Yoshida ◽  
...  
Keyword(s):  
Phase Separation ◽  
Liquid Phase ◽  
Chain Length ◽  
Alkyl Chain ◽  
Alkyl Chain Length ◽  
Liquid Phase Separation ◽  
Hydrolytic Polycondensation ◽  
Alkyl Groups ◽  
Liquid Liquid Phase Separation

Trimetoxy- and triethoxysilanes with the same n-alkyl groups yield polysilsesquioxane liquids of similar properties by cosolvent-free hydrolytic polycondensation via aging.

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