scholarly journals Design of bright near-infrared-emitting quantum dots capped with different stabilizing ligands for tumor targeting

RSC Advances ◽  
2018 ◽  
Vol 8 (8) ◽  
pp. 4221-4229 ◽  
Author(s):  
Xijing Liu ◽  
Peijiang Zhou ◽  
Hongyu Liu ◽  
Hongju Zhan ◽  
Qiang Zhang ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Tumor Targeting ◽  
Near Infrared ◽  
Diagnosis And Therapy ◽  
Stabilizing Ligands

Advanced research into biocompatible NIR-emitting QDs provides significant promise for long-term diagnosis and therapy through in vivo observations.

Glucose-functionalized near-infrared Ag2Se quantum dots with renal excretion ability for long-term in vivo tumor imaging

2019 ◽  
Vol 7 (38) ◽  
pp. 5782-5788 ◽  
Author(s):  
Xiao-Lei Ge ◽  
Biao Huang ◽  
Zhi-Ling Zhang ◽  
Xiaolan Liu ◽  
Man He ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Fluorescent Probes ◽  
Near Infrared ◽  
Renal Excretion ◽  
Tumor Imaging

Non-toxic and long-term fluorescent probes for tumor imaging are in urgent need for non-invasively obtaining information about tumor genesis and metastasis in vivo.

Biocompatible Near-Infrared Quantum Dots as Ultrasensitive Probes for Long-Term in vivo Imaging Applications

Small ◽  
2009 ◽  
Vol 5 (17) ◽  
pp. 1997-2004 ◽  
Author(s):  
Ken-Tye Yong ◽  
Indrajit Roy ◽  
Hong Ding ◽  
Earl J. Bergey ◽  
Paras N. Prasad
Keyword(s):  
Quantum Dots ◽  
In Vivo Imaging ◽  
Near Infrared

scholarly journals Time-Programmed Delivery of Sorafenib and Anti-CD47 Antibody via a Double-Layer-Gel Matrix for Postsurgical Treatment of Breast Cancer

2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Liping Huang ◽  
Yiyi Zhang ◽  
Yanan Li ◽  
Fanling Meng ◽  
Hongyu Li ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Near Infrared ◽  
Immune Escape ◽  
Regulatory Protein ◽  
In Vivo Studies ◽  
Breast Cancer Patients ◽  
Thermally Responsive ◽  
Immunosuppressive Microenvironment

AbstractThe highly immunosuppressive microenvironment after surgery has a crucial impact on the recurrence and metastasis in breast cancer patients. Programmable delivery of immunotherapy-involving combinations through a single drug delivery system is highly promising, yet greatly challenging, to reverse postoperative immunosuppression. Here, an injectable hierarchical gel matrix, composed of dual lipid gel (DLG) layers with different soybean phosphatidylcholine/glycerol dioleate mass ratios, was developed to achieve the time-programmed sequential delivery of combined cancer immunotherapy. The outer layer of the DLG matrix was thermally responsive and loaded with sorafenib-adsorbed graphene oxide (GO) nanoparticles. GO under manually controlled near-infrared irradiation generated mild heat and provoked the release of sorafenib first to reeducate tumor-associated macrophages (TAMs) and promote an immunogenic tumor microenvironment. The inner layer, loaded with anti-CD47 antibody (aCD47), could maintain the gel state for a much longer time, enabling the sustained release of aCD47 afterward to block the CD47-signal regulatory protein α (SIRPα) pathway for a long-term antitumor effect. In vivo studies on 4T1 tumor-bearing mouse model demonstrated that the DLG-based strategy efficiently prevented tumor recurrence and metastasis by locally reversing the immunosuppression and synergistically blocking the CD47-dependent immune escape, thereby boosting the systemic immune responses.

Near-infrared persistent luminescence hollow mesoporous nanospheres for drug delivery and in vivo renewable imaging

2016 ◽  
Vol 4 (48) ◽  
pp. 7845-7851 ◽  
Author(s):  
Junpeng Shi ◽  
Meng Sun ◽  
Xia Sun ◽  
Hongwu Zhang
Keyword(s):  
Drug Delivery ◽  
Near Infrared ◽  
High Sensitivity ◽  
Drug Carriers ◽  
Template Method ◽  
Persistent Luminescence ◽  
Deep Tissue ◽  
Large Capacity

Near-infrared persistent luminescence hollow mesoporous nanospheres have been synthesized via a template method. These nanospheres can be used as large capacity drug carriers and realize super long-term and high sensitivity tracking of drug delivery in deep tissue.

scholarly journals Extending the Near-Infrared Emission Range of Indium Phosphide Quantum Dots for Multiplexed In Vivo Imaging

Nano Letters ◽  
2021 ◽  
Author(s):  
Alexander M. Saeboe ◽  
Alexey Yu. Nikiforov ◽  
Reyhaneh Toufanian ◽  
Joshua C. Kays ◽  
Margaret Chern ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Indium Phosphide ◽  
In Vivo Imaging ◽  
Near Infrared ◽  
Infrared Emission ◽  
Near Infrared Emission

In Vivo Fluorescence Imaging with Ag2S Quantum Dots in the Second Near-Infrared Region

2012 ◽  
Vol 51 (39) ◽  
pp. 9818-9821 ◽  
Author(s):  
Guosong Hong ◽  
Joshua T. Robinson ◽  
Yejun Zhang ◽  
Shuo Diao ◽  
Alexander L. Antaris ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Fluorescence Imaging ◽  
Near Infrared ◽  
Infrared Region ◽  
In Vivo Fluorescence ◽  
In Vivo Fluorescence Imaging ◽  
Near Infrared Region ◽  
Ag2s Quantum Dots

Near-infrared emissive lanthanide hybridized carbon quantum dots for bioimaging applications

2016 ◽  
Vol 4 (38) ◽  
pp. 6366-6372 ◽  
Author(s):  
Fengshou Wu ◽  
Huifang Su ◽  
Xunjin Zhu ◽  
Kai Wang ◽  
Zhenfeng Zhang ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Near Infrared ◽  
Carbon Quantum Dots ◽  
Facile Preparation

Facile preparation of lanthanide hybridized carbon quantum dots (Ln-CQDs) and their potential for visible/NIR bioimagingin vivo.

scholarly journals PEGylated Phospholipid Micelle-Encapsulated Near-Infrared PbS Quantum Dots for in vitro and in vivo Bioimaging

Theranostics ◽  
2012 ◽  
Vol 2 (7) ◽  
pp. 723-733 ◽  
Author(s):  
Rui Hu ◽  
Wing-Cheung Law ◽  
Guimiao Lin ◽  
Ling Ye ◽  
Jianwei Liu ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Near Infrared ◽  
Pbs Quantum Dots
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