scholarly journals Separation performance of a large π-conjugated truxene-based dendrimer as stationary phase for gas chromatography

RSC Advances ◽  
2017 ◽  
Vol 7 (71) ◽  
pp. 44665-44672 ◽  
Author(s):  
Meng Wang ◽  
Yinhui Yang ◽  
Meiling Qi ◽  
Jinliang Wang
Keyword(s):  
Gas Chromatography ◽  
High Resolution ◽  
Stationary Phase ◽  
Separation Performance ◽  
Chromatographic Separations

High-resolution performance of a π-conjugated truxene-based dendrimer as the stationary phase for gas chromatographic separations.

A novel column modification approach for capillary gas chromatography: combination with a triptycene-based stationary phase achieves high separation performance and inertness

2021 ◽  
Author(s):  
Yongrui He ◽  
Meiling Qi
Keyword(s):  
Gas Chromatography ◽  
High Resolution ◽  
Stationary Phase ◽  
Capillary Gas Chromatography ◽  
Separation Performance ◽  
The Novel ◽  
Capillary Gc ◽  
Gc Analysis ◽  
High Separation

Integration of the novel column modification approach with a triptycene-based stationary phase achieves high-resolution performance and inertness towards acids/bases and isomers for capillary GC analysis.

Separation Performance of MOFs Zn(ISN)2·2H2O as Stationary Phase for High-Resolution GC

2013 ◽  
Vol 76 (13-14) ◽  
pp. 831-836 ◽  
Author(s):  
Xin-huan Zhang ◽  
Sheng-ming Xie ◽  
Ai-hong Duan ◽  
Bang-jin Wang ◽  
Li-Ming Yuan
Keyword(s):  
High Resolution ◽  
Stationary Phase ◽  
Separation Performance

A highly ordered chiral inorganic mesoporous material used as stationary phase for high-resolution gas chromatographic separations

2018 ◽  
Vol 1557 ◽  
pp. 99-106 ◽  
Author(s):  
Yan-Xia Li ◽  
Shi-Guo Fu ◽  
Jun-Hui Zhang ◽  
Sheng-Ming Xie ◽  
Lang Li ◽  
...  
Keyword(s):  
High Resolution ◽  
Stationary Phase ◽  
Mesoporous Material ◽  
Chromatographic Separations

scholarly journals Simple and Sensitive Methods for the Determination of 2-(4′-Chloromethyl phenyl) Benzonitrile and 2-(4′-Bromomethyl phenyl) Benzonitrile Contents in Valsartan Drug Substance by Gas Chromatography

2013 ◽  
Vol 2013 ◽  
pp. 1-5
Author(s):  
G. Amarnatha Reddy ◽  
K. Hussain Reddy ◽  
M. Narendra Kumar ◽  
Hemant kumar Sharma
Keyword(s):  
Gas Chromatography ◽  
Stationary Phase ◽  
Particle Diameter ◽  
Internal Standard ◽  
Drug Substance ◽  
Ionization Detector ◽  
Chromatographic Separations ◽  
Flame Ionization ◽  
Dimethyl Polysiloxane

Simple and reliable gas chromatographic methods were developed, optimized, and validated for the determination of 2-(4′-chloromethyl phenyl) benzonitrile (2-CMPB) and 2-(4′-bromomethyl phenyl) benzonitrile (2-BMPB) contents in valsartan drug substance, using benzophenone as internal standard (IS). Efficient chromatographic separations were achieved on DB-1, 30 m length with 0.53 mm i.d., and 3 μm particle diameter column consists of 100% dimethyl polysiloxane as a stationary phase by passing helium as a carrier gas. The analytes were extracted in dichloromethane and monitored by flame ionization detector. The performance of these methods was assessed by evaluating specificity, precision, sensitivity, linearity, and accuracy. The limits of detection (LOD) and limits of quantification (LOQ) established for 2-CMPB are 0.10 μg mL−1 and 0.32 μg mL−1, respectively. For 2-BMPB, LOD is 0.31 μg mL−1 and LOQ is 0.95 μg mL−1. The average recoveries for 2-CMPB are in the range of 96.8% to 106.7% and for 2-BMPB (LOQ level) are 99.3%. The methods can be successfully applied for the routine analysis of valsartan drug substance.

scholarly journals Amphiphilic Block Copolymer PCL-PEG-PCL as Stationary Phase for Capillary Gas Chromatographic Separations

Molecules ◽  
2019 ◽  
Vol 24 (17) ◽  
pp. 3158 ◽  
Author(s):  
Tao Sun ◽  
Xiaomin Shuai ◽  
Kaixin Ren ◽  
Xingxing Jiang ◽  
Yujie Chen ◽  
...  
Keyword(s):  
Block Copolymer ◽  
Stationary Phase ◽  
Stationary Phases ◽  
Complex Mixture ◽  
Amphiphilic Block Copolymer ◽  
Separation Performance ◽  
Chromatographic Separations ◽  
Static Coating ◽  
High Column

This work presents the first example of utilization of amphiphilic block copolymer PCL-PEG-PCL as a stationary phase for capillary gas chromatographic (GC) separations. The PCL-PEG-PCL capillary column fabricated by static coating provides a high column efficiency of 3951 plates/m for n-dodecane at 120 °C. McReynolds constants and Abraham system constants were also determined in order to evaluate the polarity and possible molecular interactions of the PCL-PEG-PCL stationary phase. Its selectivity and resolving capability were investigated by using a complex mixture covering analytes of diverse types and positional, structural, and cis-/trans-isomers. Impressively, it exhibits high resolution performance for aliphatic and aromatic isomers with diverse polarity, including those critical isomers such as butanol, dichlorobenzene, dimethylnaphthalene, xylenol, dichlorobenzaldehyde, and toluidine. Moreover, it was applied for the determination of isomer impurities in real samples, suggesting its potential for practical use. The superior separation performance demonstrates the potential of PCL-PEG-PCL and related block copolymers as stationary phases in GC and other separation technologies.

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