scholarly journals Investigation on the self-assembled behaviors of C18unsaturated fatty acids in arginine aqueous solution

RSC Advances ◽  
2017 ◽  
Vol 7 (66) ◽  
pp. 41561-41572 ◽  
Author(s):  
Yuxian Wang ◽  
Ling Jiang ◽  
Qinke Shen ◽  
Jian Shen ◽  
Yuwang Han ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Aqueous Solution ◽  
Fatty Acids ◽  
Theoretical Basis ◽  
The Self ◽  
Self Assembled

Self-assembled behaviors of UFAs in arginine solution have provided a theoretical basis for the application of two functional molecules in drug delivery.

scholarly journals Self-assembled chromogen-loaded polymeric cocoon for respiratory virus detection

Nanoscale ◽  
2021 ◽  
Vol 13 (1) ◽  
pp. 388-396
Author(s):  
Indra Memdi Khoris ◽  
Akhilesh Babu Ganganboina ◽  
Tetsuro Suzuki ◽  
Enoch Y. Park
Keyword(s):  
Aqueous Solution ◽  
Self Assembly ◽  
Respiratory Virus ◽  
Virus Detection ◽  
The Self ◽  
Signal Molecules ◽  
Self Assembled

Inspired by the self-assembly approach, in this work, the chromogen, 3,3′,5,5′-tetramethylbenzidine (TMB), was successfully co-precipitated in aqueous solution to form collective nanoparticles (NPs) of signal molecules (TMB-NPs).

scholarly journals Tuning the Hydrophobicity of a Hydrogel Using Self-Assembled Domains of Polymer Cross-Linkers

Materials ◽  
2019 ◽  
Vol 12 (10) ◽  
pp. 1635 ◽  
Author(s):  
Hee-Jin Kim ◽  
Sungwoo Cho ◽  
Seung Joo Oh ◽  
Sung Gyu Shin ◽  
Hee Wook Ryu ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Fluorescence Analysis ◽  
Building Blocks ◽  
The Self ◽  
Cell Therapies ◽  
Hydrophobically Modified ◽  
3D Matrix ◽  
Self Assembled ◽  
Cellular Microenvironments ◽  
Irregular Arrangement

Hydrogels incorporated with hydrophobic motifs have received considerable attention to recapitulate the cellular microenvironments, specifically for the bio-mineralization of a 3D matrix. Introduction of hydrophobic molecules into a hydrogel often results in irregular arrangement of the motifs, and further phase separation of hydrophobic domains, but limited efforts have been made to resolve this challenge in developing the hydrophobically-modified hydrogel. Therefore, this study presents an advanced integrative strategy to incorporate hydrophobic domains regularly in a hydrogel using self-assembled domains formed with polymer cross-linkers, building blocks of a hydrogel. Self-assemblies formed by polymer cross-linkers were examined as micro-domains to incorporate hydrophobic motifs in a hydrogel. The self-assembled structures in a pre-gelled solution were confirmed with the fluorescence analysis and the hydrophobicity of a hydrogel could be tuned by incorporating the hydrophobic chains in a controlled manner. Overall, the results of this study would greatly serve to tuning performance of a wide array of hydrophobically-modified hydrogels in drug delivery, cell therapies and tissue engineering.

A self-assembled DNA nanostructure for targeted and pH-triggered drug delivery to combat doxorubicin resistance

2016 ◽  
Vol 4 (22) ◽  
pp. 3854-3858 ◽  
Author(s):  
Juan Liu ◽  
Xiaowei Ma ◽  
Chunni Lei ◽  
Xiangdong Xue ◽  
Tuo Wei ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Cells ◽  
The Self ◽  
Doxorubicin Resistance ◽  
Dna Nanostructure ◽  
Self Assembled ◽  
Target Cancer

The self-assembled DNA nanostructure was able to specifically target cancer cells and release the drug at pH 5.0.

SANS study on self-assembled structures of Pluronic F127 triblock copolymer induced by additives and temperature

2013 ◽  
Vol 47 (1) ◽  
pp. 53-59 ◽  
Author(s):  
Tae-Hwan Kim ◽  
Young-Soo Han ◽  
Jong-Dae Jang ◽  
Baek-Seok Seong
Keyword(s):  
Aqueous Solution ◽  
Triblock Copolymer ◽  
Structural Information ◽  
Material Balance ◽  
The Self ◽  
Pluronic F127 ◽  
Spherical Micelle ◽  
Simple Material ◽  
Temperature Range ◽  
Self Assembled

In the temperature range of 303–333 K, the self-assembled structures of a mixture of Pluronic F127 triblock copolymer [PEO106PPO70PEO106; PEO is poly(ethylene oxide) and PPO is poly(propylene oxide)] and an organic derivative, 5-methyl salicylic acid (5mS), in aqueous solution have been investigated using small-angle neutron scattering (SANS). Above a 5mS concentration of 1.93 g l−1, the F127–5mS mixture solution became cloudy with a blue colour arising from the Tyndall effect, indicating that large polymer aggregates had formed in the mixture solution. SANS measurements showed that the self-assembled structure of the F127–5mS mixture transformed from a spherical to a cylindrical micelle with increasing the concentration of 5mS in the temperature range of 303–323 K. When the 5mS concentration was increased to 3.3 g l−1, the self-assembled structure of the F127–5mS mixture at 333 K underwent an additional phase transition from a cylindrical to a spherical micelle of large size at a 5mS concentration of 2.75 g l−1, although its self-assembled structure changed from a spherical to a cylindrical micelle at a 5mS concentration of 1.93 g l−1as well. The phase transitions are explained by the variation of the mass fraction of the hydrophilic part of F127 and the coupled effect of the limited solubility and the strong tendency to bind with amphiphilic molecules of 5mS. Using a simple material balance equation and the structural information obtained from SANS model analyses, the numbers of D2O and of 5mS molecules in the core and corona regions are calculated. This result can provide a simple and easy way to prepare various nanostructures using a Pluronic triblock copolymer in aqueous solution and may be very useful for practical applications of a Pluronic polymer such as various nanobuilding blocks or nanotemplates.

Self-assembly of the active lactone form of a camptothecin–phospholipid complex for sustained nuclear drug delivery

RSC Advances ◽  
2016 ◽  
Vol 6 (86) ◽  
pp. 82949-82960 ◽  
Author(s):  
Zhongxiong Fan ◽  
Guihua Liu ◽  
Yang Li ◽  
Jinyuan Ma ◽  
Jinyan Lin ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Self Assembly ◽  
The Self ◽  
Phospholipid Complex ◽  
Lactone Form ◽  
Self Assembled

(A) Illustration of the preparation of the CPT–SPC complex and its self-assembled nanoparticles (CPT–SPC NPs). (B) Illustration of drug delivery of the self-assembled CPT–SPC NPs.

Self-Assembled Coumarin Nanoparticle in Aqueous Solution as Selective Mitochondrial-Targeting Drug Delivery System

2018 ◽  
Vol 10 (4) ◽  
pp. 3380-3391 ◽  
Author(s):  
Ji Ha Lee ◽  
Ka Young Kim ◽  
Hanyong Jin ◽  
Yeong Eun Baek ◽  
Yeonweon Choi ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Aqueous Solution ◽  
Drug Delivery System ◽  
Delivery System ◽  
Mitochondrial Targeting ◽  
Self Assembled

Study of Pt Nanoparticles Protected by 1-Dodecanethiol Self-Assembled Films on Iron Surface Using Electrochemical Methods,UV-Vis and XPS Measurements

2011 ◽  
Vol 239-242 ◽  
pp. 273-278
Author(s):  
Zhe Zhang ◽  
Le Ruan ◽  
Ming Zi Jia ◽  
Ji Qiong Jiang ◽  
Xing Shen Deng
Keyword(s):  
Aqueous Solution ◽  
Electrochemical Impedance Spectroscopy ◽  
Photoelectron Spectroscopy ◽  
Electrochemical Impedance ◽  
Pt Nanoparticles ◽  
The Self ◽  
Iron Surface ◽  
X Ray ◽  
Vis Spectroscopy ◽  
Self Assembled

In this article, Pt nanoparticles protected by 1-dodecanethiol (DDT) were self-assembled on iron surface forming mixed self-assembled films. Those nanoparticles were prepared in aqueous solution and transferred from water phase to toluene phase. The self-assembled films of nanoparticles protected by DDT were prepared on iron surface. The nanoparticles were characterized by UV-vis spectroscopy. Electrochemical impedance spectroscopy (EIS), polarization curves, X-ray photoelectron spectroscopy (XPS) were applied to characterize the self-assembled films on iron surface.

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