Self-Assembled Coumarin Nanoparticle in Aqueous Solution as Selective Mitochondrial-Targeting Drug Delivery System

2018 ◽  
Vol 10 (4) ◽  
pp. 3380-3391 ◽  
Author(s):  
Ji Ha Lee ◽  
Ka Young Kim ◽  
Hanyong Jin ◽  
Yeong Eun Baek ◽  
Yeonweon Choi ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Aqueous Solution ◽  
Drug Delivery System ◽  
Delivery System ◽  
Mitochondrial Targeting ◽  
Self Assembled

scholarly journals A self-assembled RNA-triple helix hydrogel drug delivery system targeting triple-negative breast cancer

2020 ◽  
Vol 8 (16) ◽  
pp. 3527-3533 ◽  
Author(s):  
Lairong Ding ◽  
Junwei Li ◽  
Changrong Wu ◽  
Feng Yan ◽  
Xuemei Li ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Triple Negative Breast Cancer ◽  
Triple Helix ◽  
Triple Negative ◽  
Breast Cancers ◽  
Self Assembled ◽  
Rna Triple Helix

A novel RNA-triple-helix hydrogel for treatment of triple negative breast cancers (TNBCs) by incorporating RNA-triple-helix and siRNA duplexes of CXCR4 into the same RNA nanoparticles was developed, without the synthetic polycationic reagents.

scholarly journals Self-assembled pH-responsive supramolecular hydrogel for hydrophobic drug delivery

RSC Advances ◽  
2018 ◽  
Vol 8 (55) ◽  
pp. 31581-31587 ◽  
Author(s):  
Lin Wang ◽  
Xuefeng Shi ◽  
Jian Zhang ◽  
Yuejun Zhu ◽  
Jinben Wang
Keyword(s):  
Drug Delivery ◽  
Cancer Cells ◽  
Drug Delivery System ◽  
Delivery System ◽  
Hydrophobic Drug ◽  
Ph Responsive ◽  
Supramolecular Hydrogel ◽  
Self Assembled

Supramolecular hydrogel, AGC16/NTS, was used to encapsulate hydrophobic drug curcumin (Cur), constructing a pH-responsive drug delivery system; the uptake of released Cur by cancer cells also occurred.

Highly uniform self-assembled microspheres from single macromolecule self-recognition for enhanced cancer immunotherapy

2020 ◽  
Vol 56 (64) ◽  
pp. 9190-9193
Author(s):  
Xin Shen ◽  
Zhenxia Zhou ◽  
Dongmei Qi ◽  
Yanchao Li ◽  
Zhiying Zeng ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Immunotherapy ◽  
Drug Delivery System ◽  
Delivery System ◽  
Local Drug Delivery ◽  
Self Recognition ◽  
Self Assembled ◽  
Local Drug Delivery System ◽  
Highly Uniform ◽  
Single Macromolecule

Self-assembled highly uniform microspheres has been developed as a local drug delivery system for effective synergistic immunotherapy.

Pharmaceutically Active Ionic Liquid Self-Assembled Vesicles for the Application as an Efficient Drug Delivery System

ChemPhysChem ◽  
2013 ◽  
Vol 14 (15) ◽  
pp. 3454-3457 ◽  
Author(s):  
Longlong Zhang ◽  
Jing Liu ◽  
Tingting Tian ◽  
Ya Gao ◽  
Xiaoqing Ji ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Ionic Liquid ◽  
Drug Delivery System ◽  
Delivery System ◽  
Self Assembled

Development of Core-Crosslinked Micelles for Drug Delivery System

2012 ◽  
Vol 486 ◽  
pp. 449-454 ◽  
Author(s):  
Yue Zhao ◽  
Ming Tao Liang ◽  
Yoseop Kim ◽  
Xin Tan ◽  
Ling Zhang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Raft Polymerization ◽  
Poly Ethylene Glycol ◽  
Reversible Addition ◽  
Self Assembled ◽  
Poly Ethylene ◽  
Crosslinked Micelles ◽  
Glycol Methyl Ether

A polymer drug delivery system was developed using crosslinked self-assembled micelles, which form stable coreshell particles. The block copolymer, composed of poly [poly (ethylene glycol) methyl ether methacrylat-block-[poly (methyl methacrylate-p-nitrophenyl acrylate)] [P(PEGMEMA)-b-P(MMA-NPA)], was synthesized via reversible addition fragmentation chain transfer (RAFT) polymerization. The self-assembled micelles were stabilized by core crosslinking through the reaction of p-nitrophenyl acrylate with 1,8-octandiamine forming stable coreshell particles.

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