scholarly journals Molecular-level insight into the binding of arginine to a zwitterionic Langmuir monolayer

RSC Advances ◽  
2017 ◽  
Vol 7 (49) ◽  
pp. 30862-30869 ◽  
Author(s):  
Joaquín Klug ◽  
Diego Masone ◽  
Mario G. Del Pópolo
Keyword(s):  
Electrostatic Potential ◽  
Molecular Level ◽  
Langmuir Monolayer ◽  
Compression Isotherm ◽  
Lateral Mobility ◽  
Insight Into

Arginine molecules bind to a DPPC monolayer, altering the interfacial electrostatic potential and the lateral mobility of the lipids, while having little effect on the compression isotherm of the monolayer.

scholarly journals Noni fruit’s water spot appearance on the second day of harvest: a trade-off between resistance and energy

2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Tian Wu ◽  
Danyan Hu ◽  
Qingfen Wang
Keyword(s):  
Statistical Analysis ◽  
Molecular Level ◽  
Morinda Citrifolia ◽  
Transcriptome Data ◽  
Trade Off ◽  
Kegg Pathways ◽  
Available Energy ◽  
Climacteric Fruit ◽  
The Relationship ◽  
Insight Into

Abstract Background Noni (Morinda citrifolia Linn.) is a tropical tree that bears climacteric fruit. Previous observations and research have shown that the second day (2 d) after harvest is the most important demarcation point when the fruit has the same appearance as the freshly picked fruit (0 d); however, they are beginning to become water spot appearance. We performed a conjoint analysis of metabolome and transcriptome data for noni fruit of 0 d and 2 d to reveal what happened to the fruit at the molecular level. Genes and metabolites were annotated to KEGG pathways and the co-annotated KEGG pathways were used as a statistical analysis. Results We found 25 pathways that were significantly altered at both metabolic and transcriptional levels, including a total of 285 differentially expressed genes (DEGs) and 11 differential metabolites through an integrative analysis of transcriptomics and metabolomics. The energy metabolism and pathways originating from phenylalanine were disturbed the most. The upregulated resistance metabolites and genes implied the increase of resistance and energy consumption in the postharvest noni fruit. Most genes involved in glycolysis were downregulated, further limiting the available energy. This lack of energy led noni fruit to water spot appearance, a prelude to softening. The metabolites and genes related to the resistance and energy interacted and restricted each other to keep noni fruit seemingly hard within two days after harvest, but actually the softening was already unstoppable. Conclusions This study provides a new insight into the relationship between the metabolites and genes of noni fruit, as well as a foundation for further clarification of the post-ripening mechanism in noni fruit.

scholarly journals Cisplatin under oriented external electric fields: A deeper insight into electrochemotherapy at the molecular level

2020 ◽  
Author(s):  
Li Zhang ◽  
Ya‐Ling Ye ◽  
Xiao‐Ling Zhang ◽  
Xiang‐Hui Li ◽  
Qiao‐Hong Chen ◽  
...  
Keyword(s):  
Electric Fields ◽  
Molecular Level ◽  
External Electric Fields ◽  
Insight Into

scholarly journals Molecular-Level Insight into How Hydroxyl Groups Boost Catalytic Activity in CO2 Hydrogenation into Methanol

Chem ◽  
2018 ◽  
Vol 4 (3) ◽  
pp. 613-625 ◽  
Author(s):  
Yuhan Peng ◽  
Liangbing Wang ◽  
Qiquan Luo ◽  
Yun Cao ◽  
Yizhou Dai ◽  
...  
Keyword(s):  
Catalytic Activity ◽  
Molecular Level ◽  
Co2 Hydrogenation ◽  
Hydroxyl Groups ◽  
Insight Into

scholarly journals Insight into molecular-level interactions between imidazolium-based ionic liquids and cellulose combining NMR, SAXS and MD simulations

2019 ◽  
Vol 75 (a1) ◽  
pp. a268-a268
Author(s):  
Aparna Annamraju ◽  
Nicholas D. Smith ◽  
Loukas Petridis ◽  
Hugh O'Neill ◽  
Sai Venkatesh Pingali ◽  
...  
Keyword(s):  
Ionic Liquids ◽  
Molecular Level ◽  
Md Simulations ◽  
Insight Into

Wingless induces transdetermination in developing Drosophila imaginal discs

Development ◽  
1995 ◽  
Vol 121 (5) ◽  
pp. 1263-1272 ◽  
Author(s):  
L. Maves ◽  
G. Schubiger
Keyword(s):  
Molecular Level ◽  
Ectopic Expression ◽  
Imaginal Discs ◽  
Developmental Studies ◽  
New Approach ◽  
Cell Determination ◽  
Disc Cells ◽  
The Subject ◽  
Insight Into

Drosophila imaginal discs, the precursors of the adult fly appendages, have been the subject of intensive developmental studies, particularly on cell determination. Cultured disc fragments are recognized not only for the ability to maintain their determined state through extra cell divisions but also for the ability to transdetermine, or switch to the determined state of a different disc. An understanding of transdetermination at a molecular level will provide further insight into the requirements for maintaining cell determination. We find that ectopic expression of the Drosophila gene wingless induces transdetermination of foreleg imaginal disc cells to wing cells. This transdetermination occurs in foreleg discs of developing larvae without disc fragmentation. The in situ-transdetermining cells localize to the dorsal region of the foreleg disc. This wingless-induced transdetermination event is remarkably similar to the leg-to-wing switch that occurs after leg disc culture. Thus we have identified a new approach to a molecular dissection of transdetermination.

scholarly journals Spectroscopic Studies of the Salmonella enterica Adenosyltransferase Enzyme SeCobA: Molecular-Level Insight into the Mechanism of Substrate Cob(II)alamin Activation

Biochemistry ◽  
2014 ◽  
Vol 53 (50) ◽  
pp. 7969-7982 ◽  
Author(s):  
Ivan G. Pallares ◽  
Theodore C. Moore ◽  
Jorge C. Escalante-Semerena ◽  
Thomas C. Brunold
Keyword(s):  
Salmonella Enterica ◽  
Molecular Level ◽  
Spectroscopic Studies ◽  
Insight Into

scholarly journals Molecular Level Insight into Enhanced n‐Type Transport in Solution‐Printed Hybrid Thermoelectrics

2019 ◽  
Vol 9 (13) ◽  
pp. 1803469 ◽  
Author(s):  
Edmond W. Zaia ◽  
Madeleine P. Gordon ◽  
Valerie Niemann ◽  
Jaeyoo Choi ◽  
Ruchira Chatterjee ◽  
...  
Keyword(s):  
Molecular Level ◽  
Insight Into

Computer Simulation of Vesicle Fusion

2011 ◽  
Vol 474-476 ◽  
pp. 943-948
Author(s):  
Shao Gui Wu ◽  
Hong Xia Guo
Keyword(s):  
Computer Simulation ◽  
Molecular Level ◽  
Dissipative Particle Dynamics ◽  
Simulation Method ◽  
Particle Dynamics ◽  
Vesicle Fusion ◽  
Simulation System ◽  
Dynamics Simulation ◽  
Dissipative Particle Dynamics Simulation ◽  
Insight Into

A dissipative particle dynamics simulation method is used to get insight into molecular-level details of vesicle fusion in this study. For simplicity, the simulation system contains water and amphiphiles. The fusion mechanism is investigated in detail. It is found that the whole fusion process is in well agreement with the “stalk-pore” hypothesis. The dynamics of vesicle fusion is analyzed by monitoring the time evolutions of morphologies.

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