Preparation of a highly reactive polymer click reagent, PEG nitrile N-oxide, and its application in block and star polymer synthesis

2017 ◽  
Vol 8 (9) ◽  
pp. 1445-1448 ◽  
Author(s):  
Toyokazu Tsutsuba ◽  
Hiromitsu Sogawa ◽  
Toshikazu Takata
Keyword(s):  
Ethylene Glycol ◽  
Polymer Synthesis ◽  
Star Polymer ◽  
Poly Ethylene Glycol ◽  
Reactive Polymer ◽  
Poly Ethylene

The polymer nitrile N-oxide containing poly(ethylene glycol) (PEG) skeleton PEG-CNO was synthesized via a stepwise reaction.

Encapsulation of chondrocytes in injectable alkali-treated collagen gels prepared using poly(ethylene glycol)-based 4-armed star polymer

Biomaterials ◽  
2005 ◽  
Vol 26 (11) ◽  
pp. 1247-1252 ◽  
Author(s):  
Tetsushi Taguchi ◽  
Liming Xu ◽  
Hisatoshi Kobayashi ◽  
Akiyoshi Taniguchi ◽  
Kazunori Kataoka ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Star Polymer ◽  
Collagen Gels ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

scholarly journals Drug Carriers With Star Polymer Structures

2018 ◽  
pp. S293-S303 ◽  
Author(s):  
L. KOTRCHOVÁ ◽  
L. KOSTKA ◽  
T. ETRYCH
Keyword(s):  
Ethylene Glycol ◽  
Drug Carriers ◽  
Water Soluble ◽  
Star Polymer ◽  
Poly Ethylene Glycol ◽  
The Core ◽  
Polyamidoamine Dendrimers ◽  
Hydroxypropyl Methacrylamide ◽  
Poly Ethylene ◽  
Synthetic Approaches

In this review we summarize several synthetic approaches to the advanced synthesis of star-like polymer-based drug carriers. Moreover, their application as nanomedicines for therapy or the diagnosis of neoplastic diseases and their biodistribution are reviewed in detail. From a broad spectrum of star-like systems, we focus only on fully water-soluble systems, mainly based on poly(ethylene glycol) or N-(2-hydroxypropyl)methacrylamide polymer and copolymer arms and polyamidoamine dendrimers serving as the core of the star-like systems.

Poly(ethylene glycol) Star Polymer Hydrogels

1998 ◽  
Vol 31 (23) ◽  
pp. 8149-8156 ◽  
Author(s):  
Kelley Britton Keys ◽  
Fotios M. Andreopoulos ◽  
Nikolaos A. Peppas
Keyword(s):  
Ethylene Glycol ◽  
Star Polymer ◽  
Poly Ethylene Glycol ◽  
Polymer Hydrogels ◽  
Poly Ethylene

Preparation and swelling behavior of end-linked hydrogels prepared from linear poly(ethylene glycol) and dendrimer-star polymers

2021 ◽  
Vol 41 (3) ◽  
pp. 202-210
Author(s):  
Jun Wang ◽  
Guangna Qu ◽  
Xiangbin Liu ◽  
Qin Yu ◽  
Na Zhang
Keyword(s):  
Molecular Weight ◽  
Ethylene Glycol ◽  
Swelling Behavior ◽  
Star Polymer ◽  
Molar Ratio ◽  
Solution Temperature ◽  
Poly Ethylene Glycol ◽  
Dsc Measurements ◽  
Poly Ethylene ◽  
Epoxy Groups

Abstract Linear diepoxide-terminated poly(ethylene glycol) (PEG) of molar mass 600, 1000 and 2000 g mol−1 was end-linked with dendrimer-star polymer (PAMAM) of generations 1.0 in water to prepare architecturally well-defined copolymer hydrogels. The structures and properties of the products were characterized using infrared, 1H NMR, DSC measurements, scanning electron microscopy (SEM) and swelling behavior tests. The swelling behavior of these hydrogels was tested in distilled water at constant temperature and the equilibrium swelling ratio (ESR) was determined for structurally different hydrogels and various environmental conditions, which showed that ESR was influenced by the molecular weight of PEG, the molar ratio of H amine groups/epoxy groups, temperature and pH. Higher ESR was obtained for either longer-chain PEG, non-stoichiometric H amine/epoxy groups ratio, acidic pH or lower temperatures. When the hydrogel was switched from 10 °C to 65 °C and pH 3.5 to 11.5, the swelling behavior of the hydrogels showed good reversibility for swelling–deswelling. When the molecular weight of PEG was changed in the range of 600–2000, the lower critical solution temperature (LCST) of hydrogel increased from 30 to 40 °C. When the molar ratio of H amine/epoxy groups was changed, the LCST was not significantly changed.

Synthesis of a Nanostructured Star Block Copolymer with a Cyclotriphosphazene Core

2006 ◽  
Vol 6 (11) ◽  
pp. 3446-3449
Author(s):  
Jae Kook Han ◽  
Sung Tae Kim ◽  
Hyun Jung Kim ◽  
Yong Ku Kwon
Keyword(s):  
Lactic Acid ◽  
Block Copolymer ◽  
Ethylene Glycol ◽  
Sodium Salt ◽  
Star Polymer ◽  
Poly Ethylene Glycol ◽  
Block Polymer ◽  
Star Block Copolymer ◽  
Poly Ethylene ◽  
Glycol Methyl Ether

An amphiphilic star block copolymer of poly(L-lactic acid)-b-poly(ethylene glycol) (PLLA-b-PEG) was synthesized using a hexachlorocyclotriphosphazene ring (N3P3Cl6) as a core. N3P3(OC6H4-p-CHO)6 was prepared by the reaction between the hexachlorocyclotriphosphazene core and 4-hydroxybenzaldehyde sodium salt. N3P3(OC6H4-p-CH2OH)6 was then obtained by reduction of N3P3(OC6H4-p-CHO)6. N3P3(OC6H4-p-CH2OH)6 was used as an initiator to obtain a PLLA-grafted star branched polymer by polymerizing lactide, which was then treated with succinic acid to produce a carboxylated PLLA-grafted star polymer. PEG blocks were attached to a carboxylated PLLA-grafted star polymer to produce an amphiphilic PLLA-b-PEG-grafted star block polymer by additional esterification with poly(ethylene glycol methyl ether).

PIEZOELECTRIC PROPERTIES OF POLY(3-HYDROXYBUTYRATE-CO-3-HEDROXYBUTYRATE)-CO-POLY(ETHYLENE GLYCOL) PRODUCED BY CONTROLLED MICROBIOLOGICAL BIOSYNTHESIS

2019 ◽  
Vol 10 (10) ◽  
Author(s):  
Anton Bonartsev ◽  
Vera Voinova ◽  
Elizaveta Akoulina ◽  
Andrey Dudun ◽  
Irina Zharkova ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Piezoelectric Properties ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

Thermosensitives hydrogels based on poly (ethylene glycol): I. Synthesis, characterization and release

2007 ◽  
Vol 32 (5) ◽  
pp. 431-446 ◽  
Author(s):  
Tahar Bartil ◽  
Mahmoud Bounekhel ◽  
Cedric Calberg ◽  
Robert Jerome
Keyword(s):  
Ethylene Glycol ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene
Sign in / Sign up

Export Citation Format

Share Document