K2CO3 catalyzed regioselective synthesis of thieno[2,3-b]thiochromen-4-one oximes: access to the corresponding amine and nitroso derivatives

2017 ◽  
Vol 15 (26) ◽  
pp. 5625-5634 ◽  
Author(s):  
Karuna Mahato ◽  
Prasanta Ray Bagdi ◽  
Abu T. Khan
Keyword(s):  
Efficient Method ◽  
Cyclization Reaction ◽  
Regioselective Synthesis

An unprecedented and efficient method for the synthesis of useful thieno[2,3-b]thiochromen-4-one oximes is accomplished via a thio[3 + 2] cyclization reaction of 4-hydroxydithiocoumarins and trans-β-nitrostyrenes in the presence of 10 mol% K2CO3 in ethanol under reflux conditions.

Regioselective Synthesis of 2,3‐Dihydrobenzo[ f ]isoindolones via Ag‐Catalyzed Sequential Ugi 4CR/Cascade Radical Cyclization Reaction

2021 ◽  
Vol 363 (4) ◽  
pp. 1038-1043
Author(s):  
Ying‐Chun He ◽  
Yan‐Mei Yan ◽  
Zhen‐Xing Ren ◽  
Yong‐Zhao Wang ◽  
Qiang Yu ◽  
...  
Keyword(s):  
Radical Cyclization ◽  
Cyclization Reaction ◽  
Regioselective Synthesis

One-Pot Regioselective Synthesis of 2,5,6,7-Tetrahydroimidazo [1,2-a]imidazol-3-ones Starting from (Vinylimino)phosphoranes

Synlett ◽  
2019 ◽  
Vol 30 (07) ◽  
pp. 857-859 ◽  
Author(s):  
Fen Tan ◽  
Zheng-Zheng Meng ◽  
Xiao-Qin Xiong ◽  
Guo-Ping Zeng ◽  
Ming-Wu Ding
Keyword(s):  
Nucleophilic Addition ◽  
Cyclization Reaction ◽  
Regioselective Synthesis ◽  
One Pot ◽  
Tosyl Chloride ◽  
Aryl Isocyanates ◽  
Wittig Reactions

A new, one-pot, regioselective preparation of 2,5,6,7-tetrahydroimidazo[1,2-a]imidazol-3-ones by a sequential aza-Wittig/nucleophilic addition/cyclization reaction was developed. The aza-Wittig reactions of ethyl (2Z)-3-aryl-2-[(triphenylphosphoranylidene)amino] acrylates with aryl isocyanates produced carbodiimide intermediates that were then treated sequentially with 2-aminoethanol and tosyl chloride/triethylamine to give the corresponding (2Z)-2-[(substituted)benzylidene]-2,5,6,7-tetrahydro-3H-imidazo[1,2-a]imidazol-3-ones in good overall yields and with high regioselectivity.

scholarly journals Copper(i)-carbenes as key intermediates in the [3 + 2]-cyclization of pyridine derivatives with alkenyldiazoacetates: a computational study

2019 ◽  
Vol 17 (3) ◽  
pp. 646-654 ◽  
Author(s):  
Luis A. López ◽  
Javier González
Keyword(s):  
Computational Study ◽  
Cyclization Reaction ◽  
Regioselective Synthesis ◽  
Pyridine Derivatives

This work reports a computational study of the copper(i)-catalyzed regioselective synthesis of indolizine derivatives through the [3 + 2]-cyclization reaction of vinyldiazo acetates and pyridine derivatives.

Complementary and Regioselective Synthesis of Isomeric 3-[Isoxazol-3(or 5)-yl]indoles from β-Ethylthio-β-indolyl-α,β-unsaturated Ketones

Synthesis ◽  
2021 ◽  
Author(s):  
Haifeng Yu ◽  
Wenju Wang ◽  
Kehua Wang ◽  
Xue Zhang
Keyword(s):  
Efficient Method ◽  
Hydroxylamine Hydrochloride ◽  
Regioselective Synthesis ◽  
Unsaturated Ketones ◽  
Cyclocondensation Reaction

AbstractA simple and efficient method for the complementary and regioselective synthesis of isomeric 3-(isoxazol-5-yl)indoles and 3-(isoxazol-3-yl)indoles has been developed by the regioselective cyclocondensation reaction of β-ethylthio-β-indolyl-α,β-unsaturated ketones and hydroxylamine hydrochloride. It was found that the cyclocondensation reaction in the presence of excess NaOEt in refluxing EtOH gives 3-(isoxazol-5-yl)indoles in good yields, whereas using NaOAc in boiling AcOH gives 3-(isoxazol-3-yl)indoles in good yields.

Iodine monobromide catalysed regioselective synthesis of 3-arylquinolines from α-aminoacetophenones and trans-β-nitrostyrenes

2019 ◽  
Vol 17 (2) ◽  
pp. 347-353 ◽  
Author(s):  
Radhakrishna Gattu ◽  
Santa Mondal ◽  
Saghir Ali ◽  
Abu T. Khan
Keyword(s):  
Efficient Method ◽  
Regioselective Synthesis ◽  
Iodine Monobromide

A simple and efficient method for regioselective synthesis of 3-arylquinolines is described from α-aminoacetophenones and trans-β-nitrostyrenes using 20 mol% iodine monobromide as a catalyst in acetonitrile solvent at 80 °C.

Bifunctionalized Allenes, Part IX: An Efficient Method for Regioselective Synthesis of 4-Heteroatom-Functionalized Allenecarboxylates

2013 ◽  
Vol 24 (4) ◽  
pp. 322-331 ◽  
Author(s):  
Ivaylo K. Ivanov ◽  
Ivaylo D. Parushev ◽  
Valerij Ch. Christov
Keyword(s):  
Efficient Method ◽  
Regioselective Synthesis

Highly Regioselective Synthesis of Indene Derivatives Including an Allene Functional Group via Pd/C-Catalyzed Cyclization Reaction in Air

2007 ◽  
Vol 9 (18) ◽  
pp. 3527-3529 ◽  
Author(s):  
Hai-Peng Bi ◽  
Xue-Yuan Liu ◽  
Fa-Rong Gou ◽  
Li-Na Guo ◽  
Xin-Hua Duan ◽  
...  
Keyword(s):  
Functional Group ◽  
Cyclization Reaction ◽  
Regioselective Synthesis
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