Highly Regioselective Synthesis of Indene Derivatives Including an Allene Functional Group via Pd/C-Catalyzed Cyclization Reaction in Air

2007 ◽  
Vol 9 (18) ◽  
pp. 3527-3529 ◽  
Author(s):  
Hai-Peng Bi ◽  
Xue-Yuan Liu ◽  
Fa-Rong Gou ◽  
Li-Na Guo ◽  
Xin-Hua Duan ◽  
...  
Keyword(s):  
Functional Group ◽  
Cyclization Reaction ◽  
Regioselective Synthesis

Regioselective Synthesis of 2,3‐Dihydrobenzo[ f ]isoindolones via Ag‐Catalyzed Sequential Ugi 4CR/Cascade Radical Cyclization Reaction

2021 ◽  
Vol 363 (4) ◽  
pp. 1038-1043
Author(s):  
Ying‐Chun He ◽  
Yan‐Mei Yan ◽  
Zhen‐Xing Ren ◽  
Yong‐Zhao Wang ◽  
Qiang Yu ◽  
...  
Keyword(s):  
Radical Cyclization ◽  
Cyclization Reaction ◽  
Regioselective Synthesis

NHC-catalyzed oxidative cyclization reaction for the synthesis of 3-substituted phthalides

2014 ◽  
Vol 12 (15) ◽  
pp. 2388-2393 ◽  
Author(s):  
So Won Youn ◽  
Hyoung Sub Song ◽  
Jong Hyub Park
Keyword(s):  
Michael Addition ◽  
Functional Group ◽  
Addition Reaction ◽  
Oxidative Cyclization ◽  
Cyclization Reaction ◽  
Michael Addition Reaction ◽  
Stereogenic Center

An efficient NHC-catalyzed domino oxidation/oxa-Michael addition reaction of 2-alkenylbenzaldehydes has been developed to afford 3-substituted phthalides bearing a C3-stereogenic center with a broad substrate scope and wide functional group tolerance.

One-Pot Regioselective Synthesis of 2,5,6,7-Tetrahydroimidazo [1,2-a]imidazol-3-ones Starting from (Vinylimino)phosphoranes

Synlett ◽  
2019 ◽  
Vol 30 (07) ◽  
pp. 857-859 ◽  
Author(s):  
Fen Tan ◽  
Zheng-Zheng Meng ◽  
Xiao-Qin Xiong ◽  
Guo-Ping Zeng ◽  
Ming-Wu Ding
Keyword(s):  
Nucleophilic Addition ◽  
Cyclization Reaction ◽  
Regioselective Synthesis ◽  
One Pot ◽  
Tosyl Chloride ◽  
Aryl Isocyanates ◽  
Wittig Reactions

A new, one-pot, regioselective preparation of 2,5,6,7-tetrahydroimidazo[1,2-a]imidazol-3-ones by a sequential aza-Wittig/nucleophilic addition/cyclization reaction was developed. The aza-Wittig reactions of ethyl (2Z)-3-aryl-2-[(triphenylphosphoranylidene)amino] acrylates with aryl isocyanates produced carbodiimide intermediates that were then treated sequentially with 2-aminoethanol and tosyl chloride/triethylamine to give the corresponding (2Z)-2-[(substituted)benzylidene]-2,5,6,7-tetrahydro-3H-imidazo[1,2-a]imidazol-3-ones in good overall yields and with high regioselectivity.

scholarly journals Copper(i)-carbenes as key intermediates in the [3 + 2]-cyclization of pyridine derivatives with alkenyldiazoacetates: a computational study

2019 ◽  
Vol 17 (3) ◽  
pp. 646-654 ◽  
Author(s):  
Luis A. López ◽  
Javier González
Keyword(s):  
Computational Study ◽  
Cyclization Reaction ◽  
Regioselective Synthesis ◽  
Pyridine Derivatives

This work reports a computational study of the copper(i)-catalyzed regioselective synthesis of indolizine derivatives through the [3 + 2]-cyclization reaction of vinyldiazo acetates and pyridine derivatives.

Amine-catalyzed and functional group-controlled chemo- and regioselective synthesis of multi-functionalized CF3-benzene via a metal-free process

2019 ◽  
Vol 21 (22) ◽  
pp. 6179-6186 ◽  
Author(s):  
Fu Peng ◽  
Qian Zhao ◽  
Wei Huang ◽  
Shuai-Jiang Liu ◽  
Ya-Jun Zhong ◽  
...  
Keyword(s):  
Functional Group ◽  
Regioselective Synthesis ◽  
Substituted Benzenes ◽  
Metal Free ◽  
Free Process ◽  
Novel Strategy

A novel strategy for the synthesis of CF3-containing multi-substituted benzenes with high chemo- and regioselectivities under metal-free and air-tolerant conditions was established.

Regioselective Synthesis of α-Phosphinoylnaphthols through Rhodium-Catalyzed Annulation of 1-Alkynylphosphine Oxides with Sulfoxonium Ylides

Synlett ◽  
2020 ◽  
Vol 31 (15) ◽  
pp. 1482-1486
Author(s):  
Wucheng Xie ◽  
Junjun Shi ◽  
Binting Lin ◽  
Xinyi Jian ◽  
Qinhong Lin
Keyword(s):  
Functional Group ◽  
Regioselective Synthesis

α-Phosphinoylnaphthols were obtained by redox-neutral annulation­ of 1-alkynylphosphine oxides with α-carbonyl sulfoxonium ylides under rhodium(III) catalysis. This protocol shows good regio­selectivity and broad functional-group tolerance.

Iron-Catalysed Regioselective Arylsulfonylation of Quinoline N-Oxides with Sodium Arylsulfinates under Microwave Irradiation

2017 ◽  
Vol 41 (12) ◽  
pp. 705-708 ◽  
Author(s):  
Wenpeng Mai ◽  
Mingxiu Lv ◽  
Xiaofeng Zhang ◽  
Kui Lu
Keyword(s):  
Microwave Irradiation ◽  
Functional Group ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Regioselective Synthesis ◽  
One Pot ◽  
Cross Coupling Reaction

An efficient protocol for one-pot deoxygenative and regioselective synthesis of 2-arylsulfonylquinolines has been developed via iron-catalysed cross-coupling reaction of quinoline N-oxides with sodium arylsulfinates in moderate to good yields under microwave irradiation. The reactions proceeded over a broad range of substrates with good regioselectivity and functional group tolerance.

Efficient Synthesis of Indole Derivatives Containing the Tetrazole Moeity Utilizing an Ugi-Azide Post-Transformation Strategy

Synlett ◽  
2018 ◽  
Vol 29 (14) ◽  
pp. 1892-1896 ◽  
Author(s):  
Saeed Balalaie ◽  
Ali Nikbakht ◽  
Fatemeh Baghestani ◽  
Frank Rominger
Keyword(s):  
Room Temperature ◽  
Functional Group ◽  
Cyclization Reaction ◽  
Indole Derivatives ◽  
Efficient Synthesis ◽  
Efficient Strategy ◽  
High Yields ◽  
Operational Simplicity ◽  
Transformation Strategy

An efficient strategy has been developed for the synthesis of indole derivatives containing the tetrazole moiety using a AuCl3-catalyzed cyclization reaction. The precursors of the cycloadduct were easily prepared by an Ugi-azide 4-CR in methanol at room temperature. The merit of this protocol lies in its operational simplicity, readily available starting materials, high yields of product, and good functional group tolerance.

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