scholarly journals Direct palladium-mediated on-resin disulfide formation from Allocam protected peptides

2017 ◽  
Vol 15 (14) ◽  
pp. 2914-2918 ◽  
Author(s):  
Thilini D. Kondasinghe ◽  
Hasina Y. Saraha ◽  
Samantha B. Odeesho ◽  
Jennifer L. Stockdill
Keyword(s):  
Convenient Method ◽  
Direct Conversion ◽  
Solid Support ◽  
Disulfide Formation ◽  
Protected Peptides

We present a mild, convenient method for direct conversion of Allocam protected peptides to disulfide-containing protected peptides on solid support.

Direct Conversion of Esters to Hydroxyamides on Solid Support - a Key Step en route to Bisoxazoline Ligands

Synlett ◽  
2002 ◽  
Vol 2002 (02) ◽  
pp. 0247-0250
Author(s):  
Avi Weissberg ◽  
Moshe Portnoy
Keyword(s):  
Direct Conversion ◽  
Solid Support

scholarly journals A Novel, One-Step Palladium and Phenylsilane Activated Amidation from Allyl Ester on Solid Support

2008 ◽  
Vol 2008 ◽  
pp. 1-4
Author(s):  
Zheming Ruan ◽  
Katy Van Kirk ◽  
Christopher B. Cooper ◽  
R. Michael Lawrence
Keyword(s):  
Carboxylic Acid ◽  
Solid Phase ◽  
Direct Conversion ◽  
Solid Support ◽  
Phase Array ◽  
Reaction Conditions ◽  
Allyl Ester ◽  
One Step ◽  
Allyl Esters

The direct conversion of solid-supported carboxylic acid allyl esters to carboxamides through the use of phenylsilane and catalytic Pd under mild reaction conditions is reported. The use of this methodology for the generation of a 48 compound solid-phase array is described herein.

scholarly journals C-Terminally modified peptides via cleavage of the HMBA linker by O-, N- or S-nucleophiles

2016 ◽  
Vol 14 (12) ◽  
pp. 3238-3245 ◽  
Author(s):  
J. Hansen ◽  
F. Diness ◽  
M. Meldal
Keyword(s):  
Convenient Method ◽  
Modified Peptides ◽  
Nucleophilic Cleavage ◽  
Protected Peptides

A direct and convenient method for the release of protected peptides with C-terminal modification from the HMBA linker by nucleophilic cleavage with amines, alcoholates or thiolates.

The Synthesis of 2-(1,2,3-Triazol-2-yl)-1,8-Naphthyridines under Microwave Irradiation

2005 ◽  
Vol 2005 (8) ◽  
pp. 523-525 ◽  
Author(s):  
Kaleru Mogilaiah ◽  
Mullangi Prashanthi ◽  
Siddoju Kavitha ◽  
Nagavelli Vasudeva Reddy
Keyword(s):  
Acetic Anhydride ◽  
Microwave Irradiation ◽  
Convenient Method ◽  
Solid Support ◽  
Basic Alumina

An efficient and convenient method is described for the synthesis of 3-aryl-2-(4,5-dimethyl-2H-1,2,3-triazol-2-yl)-1,8-naphthyridines (4) from α-acetylacetaldoxime 3-aryl-1,8-naphthyridin-2-ylhydrazones (3) in the presence of acetic anhydride and DMF using basic alumina as solid support under microwave irradiation.

Use of the Magnetostatic Analogue In Electromagnetic Lens Engineering

1970 ◽  
Vol 28 ◽  
pp. 360-361
Author(s):  
John W. Coleman
Keyword(s):  
Boundary Conditions ◽  
High Performance ◽  
Force Fields ◽  
Optical Design ◽  
Direct Conversion ◽  
Design Engineering ◽  
Design Data ◽  
Scalar Potentials ◽  
Geometric Elements ◽  
At Will

In the design engineering of high performance electromagnetic lenses, the direct conversion of electron optical design data into drawings for reliable hardware is oftentimes difficult, especially in terms of how to mount parts to each other, how to tolerance dimensions, and how to specify finishes. An answer to this is in the use of magnetostatic analytics, corresponding to boundary conditions for the optical design. With such models, the magnetostatic force on a test pole along the axis may be examined, and in this way one may obtain priority listings for holding dimensions, relieving stresses, etc..The development of magnetostatic models most easily proceeds from the derivation of scalar potentials of separate geometric elements. These potentials can then be conbined at will because of the superposition characteristic of conservative force fields.

Thickness and composition determinations from T.E.M. specimens using both x-ray and backscattered electron data

1984 ◽  
Vol 42 ◽  
pp. 576-577
Author(s):  
M.D. Ball ◽  
H. Lagace ◽  
M.C. Thornton
Keyword(s):  
Electron Microscope ◽  
Atomic Number ◽  
Transmission Electron Microscope ◽  
Convenient Method ◽  
Flow Chart ◽  
X Ray ◽  
Intensity Measurements ◽  
Transmission Electron ◽  
Electron Intensity ◽  
Backscattered Electron

The backscattered electron coefficient η for transmission electron microscope specimens depends on both the atomic number Z and the thickness t. Hence for specimens of known atomic number, the thickness can be determined from backscattered electron coefficient measurements. This work describes a simple and convenient method of estimating the thickness and the corrected composition of areas of uncertain atomic number by combining x-ray microanalysis and backscattered electron intensity measurements.The method is best described in terms of the flow chart shown In Figure 1. Having selected a feature of interest, x-ray microanalysis data is recorded and used to estimate the composition. At this stage thickness corrections for absorption and fluorescence are not performed.

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