Neuronal adhesion and growth on nanopatterned EA5-POPC synthetic membranes

Nanoscale ◽  
2018 ◽  
Vol 10 (11) ◽  
pp. 5295-5301 ◽  
Author(s):  
Ranjita Ghosh Moulick ◽  
Gregor Panaitov ◽  
Liping Du ◽  
Dirk Mayer ◽  
Andreas Offenhäusser

Here we have fractionated synthetic membranes using metal nano-grid structures where EphrinA5 (EA5), a neuronal adhesion promoter, was anchored via its Fc domain.

2011 ◽  
Vol 39 (1) ◽  
pp. 20-43 ◽  
Author(s):  
A. Ashirgade ◽  
P. B. Harakuni ◽  
W. J. Vanooij

Abstract Adhesion between rubber compound and brass-plated steel tire cord is crucial in governing the overall performance of tires. The rubber-brass interfacial adhesion is influenced by the chemical composition and thickness of the interfacial layer. It has been shown that the interfacial layer consists mainly of sulfides and oxides of copper and zinc. This paper discusses the effect of changes in the chemical composition and the structure of the interfacial layers due to addition of adhesion promoter resins. Grazing incidence x-ray diffraction (GIXRD) experiments were run on sulfidized polished brass coupons previously bonded to five experimental rubber compounds. It was confirmed that heat and humidity conditions lead to physical and chemical changes of the rubber-steel tire cord interfacial layer, closely related to the degree of rubber-brass adhesion. Morphological transformation of the interfacial layer led to loss of adhesion after aging. The adhesion promoter resins inhibit unfavorable morphological changes in the interfacial layer, thus stabilizing it during aging and prolonging failure. Tire cord adhesion tests illustrated that the one-component resins improved adhesion after aging using a rubber compound with lower cobalt loading. Based on the acquired diffraction profiles, these resins were also found to impede crystallization of the sulfide layer after aging, leading to improved adhesion. Secondary ion mass spectrometry depth profiles and scanning electron microscopy micrographs strongly corroborated the findings from GIXRD. This interfacial analysis adds valuable information to our understanding of the complex nature of the rubber-brass bonding mechanism.


2021 ◽  
Vol 5 (6) ◽  
pp. 162
Author(s):  
Rasmeet Singh ◽  
Mandeep Singh ◽  
Nisha Kumari ◽  
Janak ◽  
Sthitapragyan Maharana ◽  
...  

Synthetic membranes are currently employed for multiple separation applications in various industries. They may have been prepared from organic or inorganic materials. Present research majorly focuses on polymeric (i.e., organic) membranes because they show better flexibility, pore formation mechanism, and thermal and chemical stability, and demand less area for installation. Dendritic, carbon nanotube, graphene and graphene oxide, metal and metal oxide, zwitter-ionic, and zeolite-based membranes are among the most promised water treatment membranes. This paper critically reviews the ongoing developments to utilize nanocomposite membranes to purify water. Various membranes have been reported to study their resistance and fouling properties. A special focus is given towards multiple ways in which these nanocomposite membranes can be employed. Therefore, this review provides a platform to develop the awareness of current research and motivate its readers to make further progress for utilizing nanocomposite membranes in water purification.


2016 ◽  
Vol 512 (1) ◽  
pp. 234-241 ◽  
Author(s):  
Alice Simon ◽  
Maria Inês Amaro ◽  
Anne Marie Healy ◽  
Lucio Mendes Cabral ◽  
Valeria Pereira de Sousa

2011 ◽  
Vol 2011 ◽  
pp. 1-3 ◽  
Author(s):  
Feyisayo Olafiranye ◽  
Win Kyaw ◽  
Oladipupo Olafiranye

Blood and dialyzer membrane interaction can cause significant thrombocytopenia through the activation of complement system. The extent of this interaction determines the biocompatibility of the membrane. Although the newer synthetic membranes have been shown to have better biocompatibility profile than the cellulose-based membranes, little is known about the difference in biocompatibility between synthetic membrane and modified cellulose membrane. Herein, we report a case of a patient on hemodialysis who developed dialyzer-membrane-related thrombocytopenia with use of synthetic membrane (F200NR polysulfone). The diagnosis of dialyzer membrane-associated thrombocytopenia was suspected by the trend of platelet count before and after dialysis, and the absence of other possible causes of thrombocytopenia. We observed significant improvement in platelet count when the membrane was changed to modified cellulose membrane (cellulose triacetate). In patients at high risk for thrombocytopenia, the modified cellulose membrane could be a better alternative to the standard synthetic membranes during hemodialysis.


Biomaterials ◽  
1997 ◽  
Vol 18 (19) ◽  
pp. 1299-1303 ◽  
Author(s):  
Nicholas A. Hoenich ◽  
Celia Woffindin ◽  
Susan Stamp ◽  
Sarah J. Roberts ◽  
Jean Turnbull

2015 ◽  
Vol 112 (27) ◽  
pp. 8187-8192 ◽  
Author(s):  
Michael D. Hardy ◽  
Jun Yang ◽  
Jangir Selimkhanov ◽  
Christian M. Cole ◽  
Lev S. Tsimring ◽  
...  

Cell membranes are dynamic structures found in all living organisms. There have been numerous constructs that model phospholipid membranes. However, unlike natural membranes, these biomimetic systems cannot sustain growth owing to an inability to replenish phospholipid-synthesizing catalysts. Here we report on the design and synthesis of artificial membranes embedded with synthetic, self-reproducing catalysts capable of perpetuating phospholipid bilayer formation. Replacing the complex biochemical pathways used in nature with an autocatalyst that also drives lipid synthesis leads to the continual formation of triazole phospholipids and membrane-bound oligotriazole catalysts from simpler starting materials. In addition to continual phospholipid synthesis and vesicle growth, the synthetic membranes are capable of remodeling their physical composition in response to changes in the environment by preferentially incorporating specific precursors. These results demonstrate that complex membranes capable of indefinite self-synthesis can emerge when supplied with simpler chemical building blocks.


Sign in / Sign up

Export Citation Format

Share Document