CC/B–N substitution in five membered heterocycles. A computational analysis

2017 ◽  
Vol 41 (9) ◽  
pp. 3619-3633 ◽  
Author(s):  
Vaibhav A. Dixit ◽  
William R. F. Goundry ◽  
Simone Tomasi
Keyword(s):  
Computational Analysis ◽  
Stabilization Energy ◽  
Stabilization Energies ◽  
Neutral Conditions ◽  
Aromatic Stabilization

Novel five-membered azaboroles are aromatic, stable under neutral conditions, isomer stabilization energy is explained using σ-bond and aromatic stabilization energies.

Effects of aromatic stabilization energies of aryl rings of symmetrical diarylethenes

Tetrahedron ◽  
2017 ◽  
Vol 73 (45) ◽  
pp. 6479-6485 ◽  
Author(s):  
Huitao Xu ◽  
Shasha Wei ◽  
Congbin Fan ◽  
Gang Liu ◽  
Shouzhi Pu
Keyword(s):  
Stabilization Energies ◽  
Aromatic Stabilization

scholarly journals Synthesis of a Highly Aromatic and Planar [10]Annulene

2021 ◽  
Author(s):  
Karnjit Parmar ◽  
Christa S. Blaquiere ◽  
Brianna Lukan ◽  
Sydnie Gengler ◽  
Michel Gravel
Keyword(s):  
Stabilization Energy ◽  
Alternative Strategy ◽  
Ring Size ◽  
Ring Strain ◽  
Aromatic Structure ◽  
Close Proximity ◽  
Ring Interaction ◽  
Aromatic Stabilization

As the next neutral structure following Hückels rule, a planar and aromatic [10]annulene is ideal to study the link between ring size and aromaticity. However, the puckered geometry of the parent [10]annulene suggests that the aromatic stabilization energy is not sufficient to overcome the ring strain that exists when the system is forced into planarity. It has been shown computationally that this ring strain can be alleviated through the addition of two or more cyclopropane rings to the periphery, thereby creating theoretically aromatic structures. An alternative strategy to eliminating the issue of ring strain was demonstrated experimentally with the successful preparation of the highly aromatic 1,6-didehydro[10]annulene. However, the system rapidly cyclizes at -40°C to a naphthalene diradical due to the close proximity of the in-plane p-orbitals present in the system. Here we show that cyclopropanating one side of the unstable annulene successfully prevents the destabilizing cross-ring interaction while maintaining a highly aromatic structure. Remarkably, the formed [10]annulene is bench stable and can be stored for extended periods of time.<br>

How Much Aromatic Naphthalene and Graphene Are?

2018 ◽  
Author(s):  
Vaibhav Dixit ◽  
Yashita Y. Singh
Keyword(s):  
Material Science ◽  
Regression Models ◽  
Experimental Validation ◽  
High Reactivity ◽  
Stabilization Energy ◽  
Reference Systems ◽  
Axis Extension ◽  
Molecular Sizes ◽  
Size Estimates ◽  
Aromatic Stabilization

<p>Naphthalene, (Aromatic stabilization Energy; ASE, 50-60 kcal/mol) polyacenes and graphene are considered aromatic. Existing models for polyacenes predict a linearly increasing ASE and give little insights into their high reactivity and decreasing stability. Graphene’s aromaticity has been studied earlier qualitatively suggesting alternate Clar’s sextet and two-electrons per ring, but ASE estimates have not been reported yet. In this paper, various Heat of Hydrogenation (HoH) and isodesmic schemes have been proposed and compared for the estimation of naphthalene ASE. Results show that HoH schemes are simple to design, are equivalent to isodesmic schemes, and unconjugated unsaturated reference systems predict ASE values in agreement with literature reports. Partially aromatic reference systems underestimate ASE. HoH schemes require calculations for a smaller number of structures, and offer scope for experimental validation, and involve enthalpy differences. Polyacene (X-axis extensions of benzene) ASE estimates (using HoH scheme) correlate well with experimental instability data and offer new physical insights explaining the absence of arbitrarily larger polyacenes. ASEs extrapolated from quadratic and logarithmic regression models have been used to estimate the largest polyacene with limiting ASE values. ASE values for Pyrene (Y-axis extension of benzene) and higher analogues (here called pyrene-vertacenes) are estimated using HoH schemes. Further truncated graphene models and graphene are approximated as combinations of polyacene and pyrene-vertacene units. First ever ASE and molecular sizes (22-255 nM) estimates predict nanometer size ranges for flat graphene in agreement with recent experiments and offer new physical insights. These ASE and size estimates for graphene may prove useful in the design of novel energy (hydrogen) storage, electronic and material science applications.</p>

On the σ,π-energy separation of the aromatic stabilization energy of cyclobutadiene

2007 ◽  
Vol 9 (20) ◽  
pp. 2517-2530 ◽  
Author(s):  
Georg Hohlneicher ◽  
Lars Packschies ◽  
Johannes Weber
Keyword(s):  
Stabilization Energy ◽  
Energy Separation ◽  
Aromatic Stabilization

Calculation of stabilization energy of parallel hexane molecules

1982 ◽  
Vol 47 (11) ◽  
pp. 3004-3012
Author(s):  
Ján Gajdoš ◽  
Tomáš Bleha
Keyword(s):  
Quantum Chemical ◽  
Molecular Crystals ◽  
Stabilization Energy ◽  
Chemical Methods ◽  
Quantum Chemical Methods ◽  
Pcilo Method ◽  
Stabilization Energies ◽  
Energy Determination ◽  
Rotational Freedom ◽  
Calculation Procedures

Molecular-mechanics method has been used for calculation od stable configurations of n-hexane pairs and triads in extended all-trans conformations with full translational and rotational freedom of the molecules during optimization. The calculated stabilization energies and equilibrium distances have been compared with the experimental data obtained for molecular crystals of paraffins. The comparison enables to distinguish the effects characteristical of the collective packing forces in the crystal. The optimum configurations of some hexane pairs have also been calculated by the quantum-chemical PCILO method. The results indicate superiority of MMC to the quantum-chemical methods and other empirical calculation procedures for the purposes of the stabilization energy determination.

Recommendations for the Evaluation of Aromatic Stabilization Energies

2002 ◽  
Vol 4 (17) ◽  
pp. 2873-2876 ◽  
Author(s):  
Paul von Ragué Schleyer ◽  
Frank Pühlhofer
Keyword(s):  
Stabilization Energies ◽  
Aromatic Stabilization
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