scholarly journals A programmable platform for sub-second multichemical dynamic stimulation and neuronal functional imaging inC. elegans

Lab on a Chip ◽  
2018 ◽  
Vol 18 (3) ◽  
pp. 505-513 ◽  
Author(s):  
T. Rouse ◽  
G. Aubry ◽  
Y. Cho ◽  
M. Zimmer ◽  
H. Lu
Keyword(s):  
Neuronal Activity ◽  
Functional Imaging ◽  
Microfluidic Platform ◽  
C Elegans ◽  
Dynamic Stimulation

This microfluidic platform enables monitoring neuronal activity ofC. elegansin response to dynamic multichemical cues.

scholarly journals Automated and controlled mechanical stimulation and functional imaging in vivo in C. elegans

Lab on a Chip ◽  
2017 ◽  
Vol 17 (15) ◽  
pp. 2609-2618 ◽  
Author(s):  
Yongmin Cho ◽  
Daniel A. Porto ◽  
Hyundoo Hwang ◽  
Laura J. Grundy ◽  
William R. Schafer ◽  
...  
Keyword(s):  
Functional Imaging ◽  
Mechanical Stimulation ◽  
Mechanical Stimuli ◽  
Microfluidic Platform ◽  
C Elegans ◽  
Neural Imaging ◽  
Wide Range

A new automated microfluidic platform can deliver a wide range of mechanical stimuli for functional neural imaging inC. elegans.

Functional imaging of neuronal activity for odor avoidance of the nematode C. elegans

2011 ◽  
Vol 71 ◽  
pp. e152
Author(s):  
Yosuke Miyanishi ◽  
Junichi Nakai ◽  
Kotaro Kimura
Keyword(s):  
Neuronal Activity ◽  
Functional Imaging ◽  
C Elegans ◽  
Odor Avoidance

scholarly journals Microfluidic Platform for Analyzing the Thermotaxis of C. elegans in a Linear Temperature Gradient

2017 ◽  
Vol 33 (12) ◽  
pp. 1435-1440 ◽  
Author(s):  
Sunhee YOON ◽  
Hailing PIAO ◽  
Tae-Joon JEON ◽  
Sun Min KIM
Keyword(s):  
Temperature Gradient ◽  
Linear Temperature ◽  
Microfluidic Platform ◽  
C Elegans ◽  
Linear Temperature Gradient

scholarly journals Correction: automated and controlled mechanical stimulation and functional imaging in vivo in C. elegans

Lab on a Chip ◽  
2017 ◽  
Vol 17 (22) ◽  
pp. 3935-3935
Author(s):  
Yongmin Cho ◽  
Daniel A. Porto ◽  
Hyundoo Hwang ◽  
Laura J. Grundy ◽  
William R. Schafer ◽  
...  
Keyword(s):  
Functional Imaging ◽  
Mechanical Stimulation ◽  
C Elegans

Correction for ‘Automated and controlled mechanical stimulation and functional imaging in vivo in C. elegans’ by Yongmin Cho et al., Lab Chip, 2017, 17, 2609–2618.

scholarly journals A Putative Cation Channel, NCA-1, and a Novel Protein, UNC-80, Transmit Neuronal Activity in C. elegans

PLoS Biology ◽  
2008 ◽  
Vol 6 (3) ◽  
pp. e55 ◽  
Author(s):  
Edward Yeh ◽  
Sharon Ng ◽  
Mi Zhang ◽  
Magali Bouhours ◽  
Ying Wang ◽  
...  
Keyword(s):  
Neuronal Activity ◽  
Cation Channel ◽  
C Elegans ◽  
Novel Protein

scholarly journals Serotonin differentially modulates Ca2+ transients and depolarization in a C. elegans nociceptor

2015 ◽  
Vol 113 (4) ◽  
pp. 1041-1050 ◽  
Author(s):  
Jeffrey A. Zahratka ◽  
Paul D. E. Williams ◽  
Philip J. Summers ◽  
Richard W. Komuniecki ◽  
Bruce A. Bamber
Keyword(s):  
Steady State ◽  
Neuronal Activity ◽  
Neuronal Excitability ◽  
Cell Soma ◽  
Voltage Gated ◽  
C Elegans ◽  
Escape Responses

Monoamines and neuropeptides modulate neuronal excitability and synaptic strengths, shaping circuit activity to optimize behavioral output. In C. elegans, a pair of bipolar polymodal nociceptors, the ASHs, sense 1-octanol to initiate escape responses. In the present study, 1-octanol stimulated large increases in ASH Ca2+, mediated by L-type voltage-gated Ca2+ channels (VGCCs) in the cell soma and L-plus P/Q-type VGCCs in the axon, which were further amplified by Ca2+ released from intracellular stores. Importantly, 1-octanol-dependent aversive responses were not inhibited by reducing ASH L-VGCC activity genetically or pharmacologically. Serotonin, an enhancer of 1-octanol avoidance, potentiated 1-octanol-dependent ASH depolarization measured electrophysiologically, but surprisingly, decreased the ASH somal Ca2+ transients. These results suggest that ASH somal Ca2+ transient amplitudes may not always be predictive of neuronal depolarization and synaptic output. Therefore, although increases in steady-state Ca2+ can reliably indicate when neurons become active, quantitative relationships between Ca2+ transient amplitudes and neuronal activity may not be as straightforward as previously anticipated.

Quantitative functional imaging of the brain: towards mapping neuronal activity by BOLD fMRI

2001 ◽  
Vol 14 (7-8) ◽  
pp. 413-431 ◽  
Author(s):  
Fahmeed Hyder ◽  
Ikuhiro Kida ◽  
Kevin L. Behar ◽  
Richard P. Kennan ◽  
Paul K. Maciejewski ◽  
...  
Keyword(s):  
Neuronal Activity ◽  
Functional Imaging ◽  
Bold Fmri ◽  
The Brain
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