scholarly journals A solid phase-assisted approach for the facile synthesis of a highly water-soluble zirconium-89 chelator for radiopharmaceutical development

2017 ◽  
Vol 46 (47) ◽  
pp. 16387-16389 ◽  
Author(s):  
Manon Briand ◽  
Margaret L. Aulsebrook ◽  
Thomas L. Mindt ◽  
Gilles Gasser
Keyword(s):  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Water Soluble ◽  
Facile Synthesis ◽  
Phase Synthesis ◽  
Bifunctional Chelator

The solid-phase synthesis of a water-soluble bifunctional chelator for 89Zr is reported.

Solid Phase Synthesis of Aromatic Oligoamides: Application to Helical Water-Soluble Foldamers

2010 ◽  
Vol 75 (21) ◽  
pp. 7175-7185 ◽  
Author(s):  
Benoît Baptiste ◽  
Céline Douat-Casassus ◽  
Katta Laxmi-Reddy ◽  
Frédéric Godde ◽  
Ivan Huc
Keyword(s):  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Water Soluble ◽  
Phase Synthesis

scholarly journals Facile synthesis of a 3-deazaadenosine phosphoramidite for RNA solid-phase synthesis

2016 ◽  
Vol 12 ◽  
pp. 2556-2562 ◽  
Author(s):  
Elisabeth Mairhofer ◽  
Elisabeth Fuchs ◽  
Ronald Micura
Keyword(s):  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Building Blocks ◽  
The Novel ◽  
Facile Synthesis ◽  
Phase Synthesis

Access to 3-deazaadenosine (c3A) building blocks for RNA solid-phase synthesis represents a severe bottleneck in modern RNA research, in particular for atomic mutagenesis experiments to explore mechanistic aspects of ribozyme catalysis. Here, we report the 5-step synthesis of a c3A phosphoramidite from cost-affordable starting materials. The key reaction is a silyl-Hilbert–Johnson nucleosidation using unprotected 6-amino-3-deazapurine and benzoyl-protected 1-O-acetylribose. The novel path is superior to previously described syntheses in terms of efficacy and ease of laboratory handling.

scholarly journals OPTIMIZATION OF MICROWAVE ASSISTED SOLID-PHASE SYNTHESIS OF OCTREOTATE PEPTIDE AND COUPLING WITH PROTECTED BIFUNCTIONAL CHELATOR DOTA(tBu)3

2020 ◽  
Vol 77 (4) ◽  
pp. 589-600
Author(s):  
Arkadiusz Sikora ◽  
Michał Maurin ◽  
Antoni Jaroń ◽  
Justyna Pijarowska – Kruszyna ◽  
Łukasz Kordowski ◽  
...  
Keyword(s):  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Phase Synthesis ◽  
Bifunctional Chelator ◽  
Microwave Assisted

Efficient solid-phase synthesis of sulfated tyrosine-containing peptides using 2-chlorotrityl resin: Facile synthesis of gastrin/cholecystokinin peptides

1997 ◽  
Vol 38 (4) ◽  
pp. 599-602 ◽  
Author(s):  
Kouki Kitagawa ◽  
Chikako Aida ◽  
Hidetoshi Fujiwara ◽  
Takeshi Yagami ◽  
Shiroh Futaki
Keyword(s):  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Facile Synthesis ◽  
Phase Synthesis

scholarly journals Facile Synthesis of a Next Generation Safety-Catch Acid-Labile Linker, SCAL-2, Suitable for Solid-Phase Synthesis, On-Support Display and for Post-Synthesis Tagging

2017 ◽  
Vol 2 (23) ◽  
pp. 6658-6662
Author(s):  
Christophe Portal ◽  
Martin Hintersteiner ◽  
Olivier Barbeau ◽  
Peter Dodd ◽  
Margaret Huggett ◽  
...  
Keyword(s):  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Next Generation ◽  
Facile Synthesis ◽  
Phase Synthesis ◽  
Post Synthesis ◽  
Acid Labile

scholarly journals Solid-Phase Synthesis of Water-Soluble Helically Folded Hybrid α-Amino Acid/Quinoline Oligoamides

2016 ◽  
Vol 81 (3) ◽  
pp. 1137-1150 ◽  
Author(s):  
Xiaobo Hu ◽  
Simon J. Dawson ◽  
Yui Nagaoka ◽  
Aya Tanatani ◽  
Ivan Huc
Keyword(s):  
Amino Acid ◽  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Water Soluble ◽  
Phase Synthesis

scholarly journals Solid-phase synthesis and evaluation of tumour-targeting phenylboronate-based MRI contrast agents

2020 ◽  
Vol 18 (39) ◽  
pp. 7899-7906
Author(s):  
Jonathan Martinelli ◽  
Rogelio Jiménez-Juárez ◽  
Diego Alberti ◽  
Simonetta Geninatti Crich ◽  
Kristina Djanashvili
Keyword(s):  
Contrast Agents ◽  
Functional Groups ◽  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Mri Contrast Agents ◽  
Water Soluble ◽  
Tumour Targeting ◽  
Mri Contrast ◽  
Phase Synthesis ◽  
Synthetic Strategy

The advantage of a solid-phase synthetic strategy with DEAM-PS resin is applied for a clean and efficient preparation of water-soluble DOTA derivatives conjugated with phenylboronic functional groups.

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