scholarly journals Solid-phase synthesis and evaluation of tumour-targeting phenylboronate-based MRI contrast agents

2020 ◽  
Vol 18 (39) ◽  
pp. 7899-7906
Author(s):  
Jonathan Martinelli ◽  
Rogelio Jiménez-Juárez ◽  
Diego Alberti ◽  
Simonetta Geninatti Crich ◽  
Kristina Djanashvili
Keyword(s):  
Contrast Agents ◽  
Functional Groups ◽  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Mri Contrast Agents ◽  
Water Soluble ◽  
Tumour Targeting ◽  
Mri Contrast ◽  
Phase Synthesis ◽  
Synthetic Strategy

The advantage of a solid-phase synthetic strategy with DEAM-PS resin is applied for a clean and efficient preparation of water-soluble DOTA derivatives conjugated with phenylboronic functional groups.

Water-soluble magnetic CoO nanocrystals functionalized with surfactants as T2-weighed MRI contrast agents in vitro

2011 ◽  
Vol 40 (14) ◽  
pp. 3616 ◽  
Author(s):  
Hong Yang ◽  
Hong Zhou ◽  
Cuixia Zhang ◽  
Xuejian Li ◽  
He Hu ◽  
...  
Keyword(s):  
Contrast Agents ◽  
Mri Contrast Agents ◽  
Water Soluble ◽  
Mri Contrast

Synthesis and characterization of a new water-soluble endohedral metallofullerene for MRI contrast agents

Carbon ◽  
2006 ◽  
Vol 44 (3) ◽  
pp. 496-500 ◽  
Author(s):  
Chun-Ying Shu ◽  
Li-Hua Gan ◽  
Chun-Ru Wang ◽  
Xin-long Pei ◽  
Hong-bin Han
Keyword(s):  
Contrast Agents ◽  
Mri Contrast Agents ◽  
Water Soluble ◽  
Synthesis And Characterization ◽  
Mri Contrast ◽  
Endohedral Metallofullerene

scholarly journals Postsynthetic On-Column 2′ Functionalization of RNA by Convenient Versatile Method

2020 ◽  
Vol 21 (14) ◽  
pp. 5127
Author(s):  
Olga A. Krasheninina ◽  
Veniamin S. Fishman ◽  
Alexander A. Lomzov ◽  
Alexey V. Ustinov ◽  
Alya G. Venyaminova
Keyword(s):  
Chemical Synthesis ◽  
Physicochemical Properties ◽  
Functional Groups ◽  
Convenient Method ◽  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Protecting Groups ◽  
Hydroxyl Group ◽  
Phase Synthesis ◽  
Wide Range

We report a universal straightforward strategy for the chemical synthesis of modified oligoribonucleotides containing functional groups of different structures at the 2′ position of ribose. The on-column synthetic concept is based on the incorporation of two types of commercial nucleotide phosphoramidites containing orthogonal 2′-O-protecting groups, namely 2′-O-thiomorpholine-carbothioate (TC, as “permanent”) and 2′-O-tert-butyl(dimethyl)silyl (tBDMS, as “temporary”), to RNA during solid-phase synthesis. Subsequently, the support-bound RNA undergoes selective deprotection and follows postsynthetic 2′ functionalization of the naked hydroxyl group. This convenient method to tailor RNA, utilizing the advantages of solid phase approaches, gives an opportunity to introduce site-specifically a wide range of linkers and functional groups. By this strategy, a series of RNAs containing diverse 2′ functionalities were synthesized and studied with respect to their physicochemical properties.

Evaluation of Water-Soluble Metallofullerenes as MRI Contrast Agents

2002 ◽  
Vol 9 (2) ◽  
pp. S495-S497 ◽  
Author(s):  
Masafumi Okumura ◽  
Masahito Mikawa ◽  
Takashi Yokawa ◽  
Yoko Kanazawa ◽  
Haruhito Kato ◽  
...  
Keyword(s):  
Contrast Agents ◽  
Mri Contrast Agents ◽  
Water Soluble ◽  
Mri Contrast

Solid Phase Synthesis of Aromatic Oligoamides: Application to Helical Water-Soluble Foldamers

2010 ◽  
Vol 75 (21) ◽  
pp. 7175-7185 ◽  
Author(s):  
Benoît Baptiste ◽  
Céline Douat-Casassus ◽  
Katta Laxmi-Reddy ◽  
Frédéric Godde ◽  
Ivan Huc
Keyword(s):  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Water Soluble ◽  
Phase Synthesis

Water-Soluble Gadofullerenes:  Toward High-Relaxivity, pH-Responsive MRI Contrast Agents

2005 ◽  
Vol 127 (2) ◽  
pp. 799-805 ◽  
Author(s):  
Éva Tóth ◽  
Robert D. Bolskar ◽  
Alain Borel ◽  
Gabriel González ◽  
Lothar Helm ◽  
...  
Keyword(s):  
Contrast Agents ◽  
Mri Contrast Agents ◽  
Water Soluble ◽  
Ph Responsive ◽  
Mri Contrast ◽  
High Relaxivity

Nanostructured magnetic nanocomposites as MRI contrast agents

2015 ◽  
Vol 3 (11) ◽  
pp. 2241-2276 ◽  
Author(s):  
Erwin Peng ◽  
Fenghe Wang ◽  
Jun Min Xue
Keyword(s):  
Contrast Agent ◽  
Contrast Agents ◽  
Magnetic Nanoparticle ◽  
Mri Contrast Agents ◽  
Water Soluble ◽  
Mri Contrast Agent ◽  
Magnetic Nanocomposites ◽  
Functional Coating ◽  
Mri Contrast ◽  
Nanoparticle Assemblies

The development of water-soluble nanostructured magnetic nanocomposites based on hydrophobic magnetic nanoparticle assemblies using an organic functional coating for MRI contrast agent applications was discussed.

scholarly journals Application of spin-crossover water soluble nanoparticles for use as MRI contrast agents

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Asami Tsukiashi ◽  
Kil Sik Min ◽  
Hikaru Kitayama ◽  
Hiroaki Terasawa ◽  
Sosuke Yoshinaga ◽  
...  
Keyword(s):  
Contrast Agents ◽  
Spin Crossover ◽  
Mri Contrast Agents ◽  
Water Soluble ◽  
Mri Contrast
Sign in / Sign up

Export Citation Format

Share Document