Recent development of luminescent rhenium(i) tricarbonyl polypyridine complexes as cellular imaging reagents, anticancer drugs, and antibacterial agents

2017 ◽  
Vol 46 (47) ◽  
pp. 16357-16380 ◽  
Author(s):  
Lawrence Cho-Cheung Lee ◽  
Kam-Keung Leung ◽  
Kenneth Kam-Wing Lo
Keyword(s):  
Anticancer Drugs ◽  
Antibacterial Agents ◽  
Cellular Imaging ◽  
Biological Applications ◽  
Recent Advances ◽  
Polypyridine Complexes

This Perspective summarizes recent advances in the biological applications of luminescent rhenium(i) tricarbonyl polypyridine complexes.

Ruthenium(ii) complexes with dppz: from molecular photoswitch to biological applications

2016 ◽  
Vol 45 (34) ◽  
pp. 13261-13276 ◽  
Author(s):  
Guanying Li ◽  
Lingli Sun ◽  
Liangnian Ji ◽  
Hui Chao
Keyword(s):  
Dna Binding ◽  
Protein Aggregation ◽  
Present Article ◽  
Anticancer Drugs ◽  
Cellular Imaging ◽  
Biological Applications ◽  
Recent Advances

The present article describes the recent advances in biological applications of the Ru-dppz systems in DNA binding, cellular imaging, anticancer drugs, phototherapy, protein aggregation detecting and chemosensors.

A REVIEW ON RECENT ADVANCES IN CHEMISTRY, SYNTHESIS AND BIOLOGICAL APPLICATIONS OF ISATIN DERIVATIVES

2018 ◽  
pp. 16-22
Author(s):  
Shukla PK ◽  
Singh MP ◽  
Patel R
Keyword(s):  
Heterocyclic Compounds ◽  
Biologically Active ◽  
Biological Applications ◽  
Plant Origin ◽  
Recent Past ◽  
Pharmacological Activities ◽  
Naturally Occurring ◽  
Recent Advances ◽  
Biological Aspects ◽  
Isatin Derivatives

Indole and its derivatives have engaged a unique place in the chemistry of nitrogen heterocyclic compounds. The recognition of the plant growthhormone, heteroauxin, the significant amino acids, tryptamine & tryptophan and anti-inflammatory drug, indomethacine are the imperativederivatives of indole which have added stimulus to this review work. Isatin (1H-indole-2,3-dione), an indole derivative of plant origin. Althoughit is a naturally occurring compound, but was synthesized by Erdmann and Laurent in 1840 before it was found in nature. Isatin is a versatileprecursor for many biologically active molecules and its diversified nature makes it a versatile substrate for further modifications. It is concernedin many pharmacological activities like anti-malarial, antiviral, anti-allergic, antimicrobial etc; isatin and its derivatives have been also found todemonstrate promising outcomes against various cancer cell lines. This review provides a brief overview on the recent advances and futureperspectives on chemistry and biological aspects of isatin and its derivatives reported in the recent past.

Engineering fluorescent semiconducting polymer nanoparticles for biological applications and beyond

2021 ◽  
Vol 57 (16) ◽  
pp. 1989-2004
Author(s):  
Junyong Sun ◽  
Qiang Zhang ◽  
Xiaomei Dai ◽  
Pinghua Ling ◽  
Feng Gao
Keyword(s):  
Polymer Nanoparticles ◽  
Biological Applications ◽  
Semiconducting Polymer ◽  
Recent Advances ◽  
Semiconducting Polymer Nanoparticles

We summarize the recent advances in engineering approaches to obtain functionalized semiconducting polymer nanoparticles (SPNs) for biological applications. The challenges and outlook of fabricating functionalized SPNs are also provided.

Research in Benzimidazole Compounds as Antibacterial Agents

2013 ◽  
Vol 781-784 ◽  
pp. 1219-1223 ◽  
Author(s):  
Jiang Ping Meng ◽  
Cheng Bo Hu ◽  
Fei Yue Wu
Keyword(s):  
Potential Application ◽  
Antibacterial Agents ◽  
Biological Activities ◽  
Foreseeable Future ◽  
Scientific Area ◽  
Recent Advances

Benzimidazole compounds are known to possess varied biological activities and so far various types of benzimidazole drugs have extensively been used in clinic. Benzimidazole compounds as a antibacterial agents has been a quite rapidly developing and is gradually becoming a relatively independent scientific area. In this paper we presented the recent advances of benzimidazole compounds as antibacterial agents. The perspective of the foreseeable future and potential application of benzimidazole as antibacterial agents are also presented.

Recent advances in biological applications of nanomaterials through defect engineering

2021 ◽  
pp. 151647
Author(s):  
Guizhu Wu ◽  
Jingyu Sun ◽  
Ze Zhang ◽  
Donggang Guo ◽  
Jiandang Liu ◽  
...  
Keyword(s):  
Biological Applications ◽  
Defect Engineering ◽  
Recent Advances

Quantum Dots Based Material for Drug Delivery Applications

2021 ◽  
pp. 191-215
Keyword(s):  
Drug Delivery ◽  
Quantum Dots ◽  
Particle Size ◽  
Physical Properties ◽  
Semiconductor Nanoparticles ◽  
Cellular Imaging ◽  
Biological Applications ◽  
Distinct Class ◽  
Imaging Probes ◽  
Biomedical Field

Quantum dots (QDs) have shown promising potential to many biomedical and biological applications, mainly in drug delivery or activation and cellular imaging. These semiconductor nanoparticles, QDs, whose particle size is in the range of 2-10 nanometer with unique photo-chemical and -physical properties that are not possessed by any other isolated molecules, have become one of the distinct class of imaging probes and worldwide platforms for manufacturing of multifunctional nanodevices. In this chapter, properties, applications of QDs, and importance in the biomedical field especially in drug delivery is presented.

scholarly journals Developments in Platinum-Group Metals as Dual Antibacterial and Anticancer Agents

2019 ◽  
Vol 2019 ◽  
pp. 1-18 ◽  
Author(s):  
Ayodele T. Odularu ◽  
Peter A. Ajibade ◽  
Johannes Z. Mbese ◽  
Opeoluwa O. Oyedeji
Keyword(s):  
Anticancer Drugs ◽  
Anticancer Agents ◽  
Coordination Compounds ◽  
Biological Activities ◽  
Platinum Group Metals ◽  
Biological Applications ◽  
Efficient Delivery ◽  
History Of ◽  
Platinum Group ◽  
Half Sandwich

Platinum-group (PG) complexes have been used as antibacterial and anticancer agents since the discovery of cisplatin. The science world still requires improvement on these complexes because of multidrug and antineoplastic resistances. This review observes discoverers and history of these platinum-group metals (PGMs), as well as their beneficial applications. The focus of this study was biological applications of PGMs in relation to human health. Sandwich and half-sandwich PGM coordination compounds and their metal nanoparticles give improved results for biological activities by enhancing efficient delivery of both antibacterial and anticancer drugs, as well as luminescent bioimaging (biomarkers) for biological identifications.

Recent advances of nanotechnology for the delivery of anticancer drugs for breast cancer treatment

2019 ◽  
Vol 50 (3) ◽  
pp. 261-270 ◽  
Author(s):  
Phuong Tran ◽  
Sang-Eun Lee ◽  
Dong-Hyun Kim ◽  
Yong-Chul Pyo ◽  
Jeong-Sook Park
Keyword(s):  
Breast Cancer ◽  
Cancer Treatment ◽  
Anticancer Drugs ◽  
Breast Cancer Treatment ◽  
Recent Advances

Recent advances in supramolecular block copolymers for biomedical applications

2020 ◽  
Vol 8 (36) ◽  
pp. 8219-8231
Author(s):  
Wumaier Yasen ◽  
Ruijiao Dong ◽  
Aliya Aini ◽  
Xinyuan Zhu
Keyword(s):  
Block Copolymers ◽  
Biomedical Applications ◽  
Future Research ◽  
Biological Applications ◽  
Research Directions ◽  
Recent Advances ◽  
Future Research Directions ◽  
Reversible Nature

Supramolecular block copolymers with a dynamically reversible nature and hierarchical microphase-separated structures can greatly enrich the library of pharmaceutical carriers and outline future research directions for biological applications.

Functionalization of cyclometalated iridium(iii) polypyridine complexes for the design of intracellular sensors, organelle-targeting imaging reagents, and metallodrugs

2015 ◽  
Vol 2 (6) ◽  
pp. 510-524 ◽  
Author(s):  
Kenneth Kam-Wing Lo ◽  
Karson Ka-Shun Tso
Keyword(s):  
Biological Applications ◽  
Polypyridine Complexes ◽  
Organelle Targeting

We summarize the biological applications of selected organometallic iridium(iii) complexes as intracellular sensors, organelle-targeting imaging reagents, and metallodrugs.

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