In situ growth of metal–organic frameworks (MOFs) on the surface of other MOFs: a new strategy for constructing magnetic resonance/optical dual mode imaging materials

2017 ◽  
Vol 46 (40) ◽  
pp. 13686-13689 ◽  
Author(s):  
Xuechuan Gao ◽  
Guanfeng Ji ◽  
Ruixue Cui ◽  
Jingjuan Liu ◽  
Zhiliang Liu
Keyword(s):  
Drug Delivery ◽  
Magnetic Resonance ◽  
Optical Imaging ◽  
Metal Organic Frameworks ◽  
In Situ Growth ◽  
Dual Mode ◽  
New Strategy ◽  
Metal Organic ◽  
First Time

This work presents for the first time the synthesis of a novel nanoscale Fe-MOF/Eu-MOF heterostructure, which exhibits excellent magnetic resonance/optical imaging capacity and satisfactory drug delivery behavior.

scholarly journals Degradation Mechanism of Porous Metal-Organic Frameworks by In Situ Atomic Force Microscopy

Nanomaterials ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 722
Author(s):  
Ioanna Christodoulou ◽  
Tom Bourguignon ◽  
Xue Li ◽  
Gilles Patriarche ◽  
Christian Serre ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Degradation Mechanism ◽  
Metal Organic Frameworks ◽  
Porous Metal ◽  
Force Microscopy ◽  
Atomic Force ◽  
Metal Organic ◽  
The Media ◽  
Ph Conditions

In recent years, Metal-Organic Frameworks (MOFs) have attracted a growing interest for biomedical applications. The design of MOFs should take into consideration the subtle balance between stability and biodegradability. However, only few studies have focused on the MOFs’ stability in physiological media and their degradation mechanism. Here, we investigate the degradation of mesoporous iron (III) carboxylate MOFs, which are among the most employed MOFs for drug delivery, by a set of complementary methods. In situ AFM allowed monitoring with nanoscale resolution the morphological, dimensional, and mechanical properties of a series of MOFs in phosphate buffer saline and in real time. Depending on the synthetic route, the external surface presented either well-defined crystalline planes or initial defects, which influenced the degradation mechanism of the particles. Moreover, MOF stability was investigated under different pH conditions, from acidic to neutral. Interestingly, despite pronounced erosion, especially at neutral pH, the dimensions of the crystals were unchanged. It was revealed that the external surfaces of MOF crystals rapidly respond to in situ changes of the composition of the media they are in contact with. These observations are of a crucial importance for the design of nanosized MOFs for drug delivery applications.

In-situ growth of ZIF-8 on gold nanoparticles/magnetic carbon nanotubes for electrochemical detection of bisphenol A

2021 ◽  
Author(s):  
Hexiang Li ◽  
Fawei Zhu ◽  
Jun Xiang ◽  
Fangbin Wang ◽  
Qi Liu ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Gold Nanoparticles ◽  
Bisphenol A ◽  
Electrochemical Detection ◽  
Metal Organic Frameworks ◽  
In Situ Growth ◽  
Metal Organic ◽  
Magnetic Carbon ◽  
Magnetic Carbon Nanotubes

We herein report a facile and scalable strategy for fabrication of the metal organic frameworks (MOFs) based composite by in-situ growing ZIF-8 on the gold nanoparticles (AuNPs) loaded magnetic carbon...

Metal–organic frameworks: a universal strategy towards super-elastic hydrogels

2019 ◽  
Vol 10 (18) ◽  
pp. 2263-2272 ◽  
Author(s):  
Huaizhi Liu ◽  
Hao Peng ◽  
Yumeng Xin ◽  
Jiuyang Zhang
Keyword(s):  
Drug Delivery ◽  
Mechanical Performance ◽  
Metal Organic Framework ◽  
Metal Organic Frameworks ◽  
High Loading ◽  
Loading Capacity ◽  
Metal Organic ◽  
First Time ◽  
Organic Framework

We reported for the first time using metal–organic framework (MOF) nanoparticles as effective nanofillers to significantly enhance the mechanical performance of hydrogels. The MOF hydrogels have been developed for drug delivery materials with high loading capacity and much extended drug releasing profiles.

Synthesis of novel mesoporous sulfated zirconia nanosheets derived from Zr-based metal–organic frameworks

CrystEngComm ◽  
2020 ◽  
Vol 22 (1) ◽  
pp. 44-51 ◽  
Author(s):  
Ningyue Lu ◽  
Xuelian Zhang ◽  
Xiaoliang Yan ◽  
Dahai Pan ◽  
Binbin Fan ◽  
...  
Keyword(s):  
Sulfated Zirconia ◽  
Metal Organic Frameworks ◽  
Metal Organic ◽  
First Time

Flower-like mesoporous sulfated zirconia nanosheets (SZNs) were developed by pyrolysis of in situ sulfated Zr-MOFs for the first time.

Magnetic Metal-Organic Frameworks: γ-Fe2O3@MOFs via Confined In Situ Pyrolysis Method for Drug Delivery

Small ◽  
2014 ◽  
Vol 10 (14) ◽  
pp. 2927-2936 ◽  
Author(s):  
Yi-nan Wu ◽  
Meimei Zhou ◽  
Shu Li ◽  
Zehua Li ◽  
Jie Li ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Metal Organic Frameworks ◽  
Pyrolysis Method ◽  
Magnetic Metal ◽  
Metal Organic
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