Laser desorption single-conformation UV and IR spectroscopy of the sulfonamide drug sulfanilamide, the sulfanilamide–water complex, and the sulfanilamide dimer

2017 ◽  
Vol 19 (22) ◽  
pp. 14625-14640 ◽  
Author(s):  
Thomas Uhlemann ◽  
Sebastian Seidel ◽  
Christian W. Müller
Keyword(s):  
Ir Spectroscopy ◽  
Noncovalent Interactions ◽  
Laser Desorption ◽  
Conformational Preference ◽  
Water Complex ◽  
Sulfonamide Drug ◽  
Sulfonamide Group

We elucidate sulfanilamide's conformational preference and the noncovalent interactions of the sulfonamide group with single-conformation IR spectroscopy.

Accessing different binding sites of a multifunctional molecule: IR spectroscopy of propargyl alcohol⋯water complexes in helium droplets

2019 ◽  
Vol 21 (37) ◽  
pp. 20582-20587 ◽  
Author(s):  
Devendra Mani ◽  
Nitish Pal ◽  
Mathias Smialkowski ◽  
Claudio Beakovic ◽  
Gerhard Schwaab ◽  
...  
Keyword(s):  
Ir Spectroscopy ◽  
Binding Sites ◽  
Local Minimum ◽  
Propargyl Alcohol ◽  
Helium Droplets ◽  
Water Complex ◽  
Alcohol Water

Helium droplets facilitate the formation of two distinct local minimum structures for 1 : 1 propargyl alcohol⋯water complex.

IR Spectroscopy of the Cesium Iodide–Water Complex

2020 ◽  
Vol 124 (32) ◽  
pp. 6528-6535 ◽  
Author(s):  
Julia A. Davies ◽  
Martin Mugglestone ◽  
Shengfu Yang ◽  
Andrew M. Ellis
Keyword(s):  
Ir Spectroscopy ◽  
Cesium Iodide ◽  
Water Complex

Site-specific binding of a water molecule to the sulfa drugs sulfamethoxazole and sulfisoxazole: a laser-desorption isomer-specific UV and IR study

2018 ◽  
Vol 20 (10) ◽  
pp. 6891-6904 ◽  
Author(s):  
Thomas Uhlemann ◽  
Sebastian Seidel ◽  
Christian W. Müller
Keyword(s):  
Ir Spectroscopy ◽  
Water Molecule ◽  
Specific Binding ◽  
Laser Desorption ◽  
Sulfa Drugs ◽  
Site Specific ◽  
Distinct Site ◽  
Ir Study

Using isomer-specific IR spectroscopy, we show that sulfamethoxazole and sulfisoxazole exhibit distinct site specificities for binding a water molecule.

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