Solventless mechanochemical preparation of novel magnetic bioconjugates

2017 ◽  
Vol 53 (54) ◽  
pp. 7635-7637 ◽  
Author(s):  
Daily Rodriguez-Padrón ◽  
Alain R. Puente-Santiago ◽  
Alina M. Balu ◽  
Antonio A. Romero ◽  
Rafael Luque
Keyword(s):  
Iron Oxide ◽  
Magnetic Nanoparticles ◽  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Mechanochemical Synthesis ◽  
Bovine Serum ◽  
Iron Oxide Magnetic Nanoparticles

A solventless mechanochemical approach was employed to obtain a bioconjugate (BSA–DA–Fe2O3) based on bovine serum albumin (BSA) and dopamine (DA) coated iron oxide magnetic nanoparticles. BSA molecules retained their native-like structure after the mechanochemical synthesis.

IMMOBILIZATION OF BSA ON DENDRIMER FUNCTIONALIZED MAGNETIC NANOPARTICLES

2011 ◽  
Vol 10 (04n05) ◽  
pp. 919-923 ◽  
Author(s):  
S. CHANDRA ◽  
N. NITHYAMATHI ◽  
P. SELVAMANI ◽  
D. BAHADUR
Keyword(s):  
Particle Size ◽  
Iron Oxide ◽  
Magnetic Nanoparticles ◽  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Ftir Spectroscopy ◽  
Magnetite Nanoparticles ◽  
Bovine Serum ◽  
Oxide Nanoparticles ◽  
Functionalized Magnetic Nanoparticles

Iron oxide nanoparticles were prepared and functionalized by succinamide based dendrimer. The resultant particles were characterized by XRD, VSM, and FTIR spectroscopy. The results indicate that the dendrimers has effectively functionalized the magnetite nanoparticles which remain dispersive and exhibited super-paramagnetism with a magnetization value of 33.2 emu/g in a field of 2T. Mean particle size as calculated from the AFM was found to be ~ 23 nm. Bovine serum albumin was immobilized on the magnetic nanoparticles as was confirmed by the FTIR results.

Degradation of BSA Coating on Magnetite Nanoparticles

2014 ◽  
Vol 782 ◽  
pp. 607-610 ◽  
Author(s):  
Kornel Csach ◽  
Alena Juríková ◽  
Jozef Miškuf ◽  
Martina Koneracká ◽  
Vlasta Závišová ◽  
...  
Keyword(s):  
Magnetic Nanoparticles ◽  
Thermogravimetric Analysis ◽  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Magnetite Nanoparticles ◽  
Bovine Serum ◽  
Magnetic Particle ◽  
Particle Surface ◽  
Protein Bovine Serum Albumin

Magnetic nanoparticles used in biomedicine have to be biocompatible what can be achieved by the modification of the magnetic particle surface with an appropriate biocompatible substance. In the work protein bovine serum albumin (BSA) was chosen to modify the surface of magnetite nanoparticles. BSA coated magnetite nanoparticles (MFBSA) with different feed weight ratios of BSA to the magnetite Fe3O4were prepared and thermally characterized using thermogravimetric analysis.

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