Variation of the bone forming ability with the physicochemical properties of calcium phosphate bone substitutes

2018 ◽  
Vol 6 (1) ◽  
pp. 136-145 ◽  
Author(s):  
Rongquan Duan ◽  
Davide Barbieri ◽  
Xiaoman Luo ◽  
Jie Weng ◽  
Chongyun Bao ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Physicochemical Properties ◽  
Surface Structure ◽  
Protein Adsorption ◽  
Calcium Ion ◽  
Bone Substitutes ◽  
Ion Release ◽  
Adsorption Surface

The submicron-scaled surface structure triggers osteoinduction in CaPs via mechanotransduction, rather than protein adsorption, surface mineralization and calcium ion release.

Amorphous Calcium Phosphate Based Polymeric Composites: Effects of Polymer Composition and Filler's Particle Size on Composite Properties

2005 ◽  
Vol 284-286 ◽  
pp. 737-740 ◽  
Author(s):  
Drago Skrtic ◽  
S.Y. Lee ◽  
Joseph M. Antonucci ◽  
D.W. Liu
Keyword(s):  
Particle Size ◽  
Calcium Phosphate ◽  
Physicochemical Properties ◽  
Amorphous Calcium Phosphate ◽  
Fine Tuning ◽  
Polymer Composition ◽  
Ion Release ◽  
The Matrix ◽  
Carboxylic Groups ◽  
Composite Properties

This study explores how a) the resin grafting potential for amorphous calcium phosphate (ACP) and b) particle size of ACP affects physicochemical properties of composites. Copolymers and composites were evaluated for biaxial flexure strength (BFS), degree of vinyl conversion (DC), mineral ion release and water sorption (WS). Milled ACP composites were superior to unmilled ACP composites and exhibited 62 % and 77 % higher BFS values (dry and wet state, respectively). The average DC of copolymers 24 h after curing was 80 %. DC of composites decreased 10.3 % for unmilled Zr-ACP and 4.6 % for milled Zr-ACP when compared to the corresponding copolymers. The WS increased as follows: copolymers < milled Zr-ACP composites < unmilled Zr-ACP composites. The levels of Ca and PO4 released from both types of composites increased with the increasing EBPADMA/TEGDMA ratio in the matrix. They were significantly above the minimum necessary for the redeposition of HAP to occur. No significant consumption of released calcium by the carboxylic groups of methacryloxyethyl phtahalate (MEP) occurred at a mass fraction of 2.6 % of MEP in the resin. Improvements in ACP composite’s physicochemical properties are achieved by fine tuning of the resin and improved ACP’s dispersion within the polymer matrix after ball-milling.

scholarly journals Evaluation of pH, Calcium Ion Release, and Dimensional Stability of an Experimental Silver Nanoparticle-Incorporated Calcium Silicate-Based Cement

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Teena Sheethal Dsouza ◽  
Aditya Shetty ◽  
Neevan Dsouza
Keyword(s):  
Physicochemical Properties ◽  
Dimensional Stability ◽  
Calcium Ion ◽  
Calcium Silicate ◽  
Filling Material ◽  
Ion Release ◽  
Filling Materials ◽  
Sample Test ◽  
Initial Ph ◽  
Experimental Group

An experimental calcium silicate-based root-end filling material incorporated with silver nanoparticles intended for use in periapical surgeries was developed with the purpose to overcome the drawbacks of existing materials and to satisfy the ideal requirements of root-end filling materials. This study was designed to evaluate the physicochemical properties, pH, calcium ion release, and dimensional stability of the experimental cement, and compare the results with commercially available ProRoot MTA (Dentsply). An independent sample test was used to analyze the data. Mean initial pH (immediately after mixing) of the experimental cement was 10.42 ± 0.04 which was higher than that of MTA. However, there was a significant increase in pH of MTA at 1 day, 2 days, and 7 days. Presence of calcium chloride favored the release of calcium ions which was significantly increased in the experimental group at 24 hours. At the end of 30 days, MTA showed a significant expansion when compared to the experimental cement p < 0.001 . In conclusion, the experimental nanoparticle-incorporated calcium silicate-based cement showed clinically acceptable physicochemical properties.

scholarly journals Evaluation of Physicochemical Properties of New Calcium Silicate-Based Sealer

2018 ◽  
Vol 29 (6) ◽  
pp. 536-540 ◽  
Author(s):  
Aline Teixeira Mendes ◽  
Paula Barcellos da Silva ◽  
Bruna Barcelos Só ◽  
Lina Naomi Hashizume ◽  
Rodrigo Ricci Vivan ◽  
...  
Keyword(s):  
Physicochemical Properties ◽  
Calcium Ion ◽  
Calcium Silicate ◽  
Calcium Release ◽  
Setting Time ◽  
Porto Alegre ◽  
Ion Release ◽  
Ph Values ◽  
Time Flow ◽  
Ah Plus

Abstract This study aimed to evaluate the physicochemical properties of a calcium silicate-based sealer (Sealer Plus BC; MK Life, Porto Alegre, Brazil) compared with an epoxy-resin sealer (AH Plus; Dentsply DeTrey GmbH, Konstanz, Germany). Initial and final setting time was assessed based on ISO 6876:2012 and ASTM C266:03. Calcium ion release and pH were evaluated by filling polyethylene tubes with sealers and then immersing them in 10 mL of deionized water. Following experimental periods of 1, 24, 72 and 168 hours, the samples were measured regarding pH and calcium ion release with a pH meter and a colorimetric spectrophotometer, respectively. The flow was examined based on ISO 6876:2012. Rings of 10 mm in diameter with 1 mm thickness were prepared to analyze the radiopacity (ISO 6876:2012 and ADA n.57) and solubility (ISO 6876:2012). The data were analyzed by variance analysis, Student-T and Tukey tests (p<0.05). The calcium ion release and pH values were significantly higher for the Sealer Plus BC compared with the AH Plus (p<0.05). Lower setting time, flow and radiopacity were observed for the bioceramic sealer than for AH Plus (p<0.05). Sealer Plus BC exhibited higher solubility compared with AH Plus (p<0.05). Sealer Plus BC showed physicochemical properties as setting time, pH, calcium release, flow, and radiopacity following the required standards, but higher solubility than the minimum values required by ISO 6876:2012.

scholarly journals The role of calcium ion release on biocompatibility and antimicrobial properties of hydraulic cements

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Andreas Koutroulis ◽  
Sarah A. Kuehne ◽  
Paul R. Cooper ◽  
Josette Camilleri
Keyword(s):  
Antibacterial Activity ◽  
Calcium Phosphate ◽  
Calcium Hydroxide ◽  
Calcium Ion ◽  
Antimicrobial Properties ◽  
Antimicrobial Effect ◽  
Hydration Reaction ◽  
Ion Release ◽  
Micro Silica

AbstractTricalcium silicate (TCS)-based materials produce calcium hydroxide as a byproduct of their hydration reaction. The present study investigated whether calcium ion release (CIR) affects their biological and antimicrobial properties when used as pulp protection materials. The effect of incorporation of micro-silica and calcium phosphate monobasic to radiopacified TCS-based materials was investigated. The commercial TCS-based Biodentine, Bio-C Pulpo, TotalFill Root Repair Material, TheraCal LC and a base/liner- ACTIVA BioACTIVE (Activa) were also evaluated. The hydration and CIR were monitored and correlated with biocompatibility and antimicrobial assessment of eluates. Overall, the additives altered the hydration and leaching profile of the prototype cements. The micro-silica inclusion resulted in a decreased long-term calcium hydroxide formation which was associated with neutralised cytotoxicity and antibacterial activity. Calcium phosphate did not alter the leaching profile, although a stronger antibacterial effect was induced. The commercial materials also had different CIR profiles. The water-based ones had higher CIR, and this was associated with stronger antimicrobial effect but not enhanced biological activity. Both TheraCal LC and Activa exhibited poor degree of conversion, low CIR, acceptable biocompatibility and moderate antibacterial activity. A positive correlation of CIR with antibacterial effectiveness was observed (0.3 < r < 0.49; p = 0.021, p = 0.011 for the two test bacterial cultures). No relation was shown between CIR and cytotoxicity (0.3 < r < 0.49; p = 0.150, p = 0.068 for the two cell cultures studied). The additives modified the CIR. The antimicrobial properties were dependent on the CIR; the cytotoxicity of the materials was unaffected.

scholarly journals Ion release and recharge from a fissure sealant containing amorphous calcium phosphate

PLoS ONE ◽  
2020 ◽  
Vol 15 (11) ◽  
pp. e0241272
Author(s):  
Mahtab Memarpour ◽  
Neda Afzali Baghdadabadi ◽  
Azade Rafiee ◽  
Mehrdad Vossoughi
Keyword(s):  
Calcium Phosphate ◽  
Amorphous Calcium Phosphate ◽  
Calcium Ion ◽  
Ion Release ◽  
Three Solutions ◽  
Fissure Sealant ◽  
Phosphate Ion ◽  
Phosphate Ions ◽  
Release Capacity ◽  
Casein Phosphopeptide

To assess- the release of calcium and phosphate ions from a fissure sealant containing amorphous calcium phosphate (ACP), and to determine the re-release capacity of these ions when charged with a solution containing casein phosphopeptide-amorphous calcium phosphate (CPP-ACP). Nine blocks of ACP resin-based sealant were prepared and immersed in three solutions at different pH (4.0, 5.5, 7.0), and calcium and phosphate ion release was measured with ion chromatography at 1, 3, 5, 7, 14, 21 and 28 days after immersion. Sixty days after immersion, each block was charged with CPP-ACP solution in three 7-day cycles to investigate the re-release of these ions, which was measured on days 1, 3, and 7. No difference was observed in initial calcium ion release at pH 4.0 and pH 5.5. At both values, ion release was significantly higher than at pH 7.0 (p<0.001). Initial phosphate release was significantly different among the three pH values (p<0.001). After re-charging the specimens, calcium ion re-release was greater than phosphate ion release. Initial ion release from ACP resin-based sealant was greatest at the lowest pH. Ion release decreased with time. As the number of recharge cycles increased, ion re-release also improved. Phosphate ion re-release required more recharge cycles than calcium ion re-release.

scholarly journals Correction: Rajasekharan, S., et al. Effect of Exposed Surface Area, Volume and Environmental pH on the Calcium Ion Release of Three Commercially Available Tricalcium Silicate Based Dental Cements. Materials 2018, 11, 123

Materials ◽  
2021 ◽  
Vol 14 (2) ◽  
pp. 340
Author(s):  
Sivaprakash Rajasekharan ◽  
Chris Vercruysse ◽  
Luc Martens ◽  
Ronald Verbeeck
Keyword(s):  
Surface Area ◽  
Calcium Ion ◽  
Tricalcium Silicate ◽  
Exposed Surface ◽  
Ion Release ◽  
Exposed Surface Area

The authors wish to make the following correction to the paper [...]

Polymer-calcium phosphate cement composites for bone substitutes

2002 ◽  
Vol 61 (4) ◽  
pp. 581-592 ◽  
Author(s):  
Rafal A. Mickiewicz ◽  
Anne M. Mayes ◽  
David Knaack
Keyword(s):  
Calcium Phosphate ◽  
Calcium Phosphate Cement ◽  
Bone Substitutes ◽  
Cement Composites
Sign in / Sign up

Export Citation Format

Share Document