Polymer-calcium phosphate cement composites for bone substitutes

2002 ◽  
Vol 61 (4) ◽  
pp. 581-592 ◽  
Author(s):  
Rafal A. Mickiewicz ◽  
Anne M. Mayes ◽  
David Knaack
Keyword(s):  
Calcium Phosphate ◽  
Calcium Phosphate Cement ◽  
Bone Substitutes ◽  
Cement Composites

scholarly journals Effect of Polymer Molecular Weight on the Bone Biological Activity of Biodegradable Polymer/Calcium Phosphate Cement Composites

2009 ◽  
Vol 15 (10) ◽  
pp. 3183-3191 ◽  
Author(s):  
Esther W.H. Bodde ◽  
Wouter J.E.M. Habraken ◽  
Antonios G. Mikos ◽  
Paul H.M. Spauwen ◽  
John A. Jansen
Keyword(s):  
Molecular Weight ◽  
Biological Activity ◽  
Calcium Phosphate ◽  
Calcium Phosphate Cement ◽  
Biodegradable Polymer ◽  
Cement Composites ◽  
Polymer Molecular Weight

scholarly journals Polymeric-Calcium Phosphate Cement Composites-Material Properties:In VitroandIn VivoInvestigations

2010 ◽  
Vol 2010 ◽  
pp. 1-14 ◽  
Author(s):  
Rania M. Khashaba ◽  
Mervet M. Moussa ◽  
Donald J. Mettenburg ◽  
Frederick A. Rueggeberg ◽  
Norman B. Chutkan ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Calcium Phosphate Cement ◽  
Setting Time ◽  
Cement Composites ◽  
Tetracalcium Phosphate ◽  
Methyl Vinyl Ether ◽  
Orthopedic Applications ◽  
Hydroxyapatite Cement

New polymeric calcium phosphate cement composites (CPCs) were developed. Cement powder consisting of 60 wt% tetracalcium phosphate, 30 wt% dicalcium phosphate dihydrate, and 10 wt% tricalcium phosphate was combined with either 35% w/w poly methyl vinyl ether maleic acid or polyacrylic acid to obtain CPC-1 and CPC-2. The setting time and compressive and diametral tensile strength of the CPCs were evaluated and compared with that of a commercial hydroxyapatite cement.In vitrocytotoxicity andin vivobiocompatibility of the two CPCs and hydroxyapatite cement were assessed. The setting time of the cements was 5–15 min. CPC-1 and CPC-2 showed significantly higher compressive and diametral strength values compared to hydroxyapatite cement. CPC-1 and CPC-2 were equivalent to Teflon controls after 1 week. CPC-1, CPC-2, and hydroxyapatite cement elicited a moderate to intense inflammatory reaction at 7 days which decreased over time. CPC-1 and CPC-2 show promise for orthopedic applications.

Controlled release of rhBMP-2 loaded poly(dl-lactic-co-glycolic acid)/calcium phosphate cement composites in vivo

2005 ◽  
Vol 106 (1-2) ◽  
pp. 162-171 ◽  
Author(s):  
P.Q. Ruhé ◽  
O.C. Boerman ◽  
F.G.M. Russel ◽  
P.H.M. Spauwen ◽  
A.G. Mikos ◽  
...  
Keyword(s):  
Controlled Release ◽  
Calcium Phosphate ◽  
Calcium Phosphate Cement ◽  
Glycolic Acid ◽  
Cement Composites

RHBMP-2 RELEASE FROM INJECTABLE POLY(DL-LACTIC-CO-GLYCOLIC ACID)/CALCIUM-PHOSPHATE CEMENT COMPOSITES

2003 ◽  
Vol 85 ◽  
pp. 75-81 ◽  
Author(s):  
QUINTEN P. RUHE ◽  
ELIZABETH L. HEDBERG ◽  
NESTOR TORIO PADRON ◽  
PAUL H.M. SPAUWEN ◽  
JOHN A. JANSEN ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Calcium Phosphate Cement ◽  
Glycolic Acid ◽  
Cement Composites

Calcium phosphate cement composites in revision hip arthroplasty

Biomaterials ◽  
2005 ◽  
Vol 26 (35) ◽  
pp. 7310-7318 ◽  
Author(s):  
Andrew D. Speirs ◽  
Thomas R. Oxland ◽  
Bassam A. Masri ◽  
Anoush Poursartip ◽  
Clive P. Duncan
Keyword(s):  
Calcium Phosphate ◽  
Hip Arthroplasty ◽  
Calcium Phosphate Cement ◽  
Revision Hip Arthroplasty ◽  
Cement Composites

Controlled Release of rhBMP-2 Loaded Poly(DL-lactic-co-glycolic Acid)/ Calcium Phosphate Cement Composites In Vivo

2006 ◽  
pp. 973-976
Author(s):  
P.Q. Ruhé ◽  
O.C. Boerman ◽  
F.G.M. Russel ◽  
P.H.M. Spauwen ◽  
Antonious G. Mikos ◽  
...  
Keyword(s):  
Controlled Release ◽  
Calcium Phosphate ◽  
Calcium Phosphate Cement ◽  
Glycolic Acid ◽  
Cement Composites
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