Gold nanoparticle aggregation enables colorimetric sensing assays for enzymatic decarboxylation

2017 ◽  
Vol 9 (19) ◽  
pp. 2784-2787 ◽  
Author(s):  
Mohamed Nilam ◽  
Andreas Hennig ◽  
Werner M. Nau ◽  
Khaleel I. Assaf

Monitoring enzymatic processes is of fundamental importance for the understanding of the associated biological phenomena.

2016 ◽  
Vol 52 (22) ◽  
pp. 4167-4170 ◽  
Author(s):  
Chia-Chen Chang ◽  
Chie-Pein Chen ◽  
Chen-Yu Chen ◽  
Chii-Wann Lin

A label-free and enzyme-free colorimetric sensing platform for the amplified detection of fibronectin was developed based on an ingenious combination of catalytic hairpin assembly and a base stacking hybridization-based gold nanoparticle aggregation strategy.


2009 ◽  
Vol 27 (10) ◽  
pp. 1855-1859 ◽  
Author(s):  
Xueping Liu ◽  
Zhenhua Zhou ◽  
Liangliang Zhang ◽  
Zhongyang Tan ◽  
Guoli Shen ◽  
...  

2021 ◽  
Author(s):  
Yiren Cao ◽  
Jinjun Wu ◽  
Bo Pang ◽  
Hongquan Zhang ◽  
X. Chris Le

The trans-cleavage activity of the target-activated CRISPR-Cas12a liberated an RNA crosslinker from a molecular transducer, which facilitated assembly of gold nanoparticles. Integration of the molecular transducer with isothermal amplification and...


The Analyst ◽  
2019 ◽  
Vol 144 (18) ◽  
pp. 5486-5496 ◽  
Author(s):  
Xue Mi ◽  
Elizabeth M. Lucier ◽  
Dylan G. Turpeinen ◽  
Eugenia Li Ling Yeo ◽  
James Chen Yong Kah ◽  
...  

Addition of osmolytes causes viruses-coated AuNPs to aggregate and not protein-coated AuNPs. Ligand-free detection of virus was developed without the need for prior knowledge of the specific virus target.


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