scholarly journals CRISPR/Cas12a-mediated gold nanoparticle aggregation for colorimetric detection of SARS-CoV-2

2021 ◽  
Author(s):  
Yiren Cao ◽  
Jinjun Wu ◽  
Bo Pang ◽  
Hongquan Zhang ◽  
X. Chris Le
Keyword(s):  
Gold Nanoparticles ◽  
Gold Nanoparticle ◽  
Colorimetric Detection ◽  
Isothermal Amplification ◽  
Nanoparticle Aggregation ◽  
Cleavage Activity ◽  
Gold Nanoparticle Aggregation

The trans-cleavage activity of the target-activated CRISPR-Cas12a liberated an RNA crosslinker from a molecular transducer, which facilitated assembly of gold nanoparticles. Integration of the molecular transducer with isothermal amplification and...

Gold nanoparticle aggregation: Colorimetric detection of the interactions between avidin and biotin

Talanta ◽  
2018 ◽  
Vol 185 ◽  
pp. 106-112 ◽  
Author(s):  
Dongmin Shi ◽  
Feifan Sheng ◽  
Xiaojun Zhang ◽  
Guangfeng Wang
Keyword(s):  
Gold Nanoparticle ◽  
Colorimetric Detection ◽  
Nanoparticle Aggregation ◽  
Gold Nanoparticle Aggregation
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