Multiplex detection of cardiac biomarkers

2017 ◽  
Vol 9 (25) ◽  
pp. 3773-3776 ◽  
Author(s):  
Mukesh Digambar Sonawane ◽  
Satish Balasaheb Nimse ◽  
Keum-Soo Song ◽  
Taisun Kim
Keyword(s):  
Cardiac Biomarkers ◽  
Cardiac Markers ◽  
Multiplex Detection

A method for multiplex detection of three cardiac markers cTnI, NT-proBNP, and cTnT specific to CVD is reported.

scholarly journals Blu-ray Technology-Based Quantitative Assays for Cardiac Markers: From Disc Activation to Multiplex Detection

2016 ◽  
Vol 88 (13) ◽  
pp. 6889-6896 ◽  
Author(s):  
Samuel Weng ◽  
Xiaochun Li ◽  
Michelle Niu ◽  
Bixia Ge ◽  
Hua-Zhong Yu
Keyword(s):  
Cardiac Markers ◽  
Multiplex Detection

scholarly journals Cardiac markers in five different breeds of rabbits (Oryctolagus cuniculus Linnaeus, 1758) used for cardiovascular research

2016 ◽  
Vol 36 (8) ◽  
pp. 737-742 ◽  
Author(s):  
Felipp S. Ferreira ◽  
Flávia L. Barretto ◽  
Arianne Fabres ◽  
Leonardo S. Silveira ◽  
Claudio B. Carvalho
Keyword(s):  
Normal Values ◽  
Heart Diseases ◽  
Large Population ◽  
Reference Interval ◽  
Cardiac Biomarkers ◽  
Cardiac Markers ◽  
Physiological Variable ◽  
Cardiovascular Research ◽  
Tukey Test ◽  
Commercial Kits

Abstract: Cardiac biomarkers for clinical and experimental heart diseases have previously been evaluated in rabbits. However, several laboratory assays performed and reported with inconsistent results. This study aimed to assess the effects of breed on serum ANP, CRP, and ACE and establish reference interval (RI) for these biomarkers in a large population of healthy rabbits. Ninety-seven adult rabbits from five breeds were included in this study. Assays were performed using specific ELISA commercial kits. The results were statistically analyzed using ANOVA, Tukey test (p<0.05), arithmetic mean, RI of mean, and standard deviation. A significant effect of breed was shown, indicating different RI between breeds for each biomarker. In conclusion, this study demonstrated that breed is an important physiological variable influencing the normal values of cardiac markers in healthy rabbits.

scholarly journals Paper-based cascade cationic isotachophoresis: Multiplex detection of cardiac markers

Talanta ◽  
2019 ◽  
Vol 205 ◽  
pp. 120112 ◽  
Author(s):  
Shuang Guo ◽  
William Schlecht ◽  
Lei Li ◽  
Wen-Ji Dong
Keyword(s):  
Cardiac Markers ◽  
Multiplex Detection

scholarly journals Correlation of Serum Cardiac Markers with Acute Decompensating Events in Liver Cirrhosis

2020 ◽  
Vol 2020 ◽  
pp. 1-15
Author(s):  
Miaomiao Li ◽  
Zeqi Guo ◽  
Dan Zhang ◽  
Xiangbo Xu ◽  
Fernando Gomes Romeiro ◽  
...  
Keyword(s):  
Creatine Kinase ◽  
Liver Cirrhosis ◽  
Gastrointestinal Hemorrhage ◽  
Troponin T ◽  
Cardiac Biomarkers ◽  
Cardiac Markers ◽  
Cross Sectional ◽  
Ctnt Level ◽  
Creatine Kinase Mb ◽  
Cirrhotic Patients

Background and Aim. Liver cirrhosis is often accompanied by insidious cardiac dysfunction. This retrospective cross-sectional study is aimed at exploring the correlation between serum cardiac markers and decompensating events in liver cirrhosis. Methods. Cirrhotic patients who were consecutively hospitalized between January 2016 and March 2019 were screened. Serum cardiac biomarkers at admission, including N-Terminal pro-B-type natriuretic peptide (NT-pro BNP), high-sensitivity cardiac troponin T (hs-cTnT), creatine kinase (CK), creatine kinase MB (CK-MB), and lactate dehydrogenase (LDH), were collected. Acute decompensating events at admission, primarily including ascites, acute gastrointestinal hemorrhage, and acute-on-chronic liver failure (ACLF), were recorded. Results. The NT-pro BNP level was significantly higher in cirrhotic patients with acute decompensating events than in those without any decompensating events (median: 140.75 pg/mL versus 41.86 pg/mL, P<0.001). The NT-pro BNP level significantly correlated with ascites, acute gastrointestinal hemorrhage, and ACLF. The hs-cTnT level was significantly higher in cirrhotic patients with acute decompensating events than in those without decompensating events (median: 0.008 ng/mL versus 0.006 ng/mL, P=0.007). The hs-cTnT level significantly correlated with acute gastrointestinal hemorrhage, but not ascites or ACLF. LDH (185.0 U/L versus 173.5 U/L, P=0.281), CK (71 U/L versus 84 U/L, P=0.157), and CK-MB (29.5 U/L versus 33.0 U/L, P=0.604) levels were not significantly different between cirrhotic patients with and without acute decompensating events. Conclusion. The elevated NT-pro BNP level seems to be closely related to the development of acute decompensating events in liver cirrhosis.

Cardiac biomarkers in goats with experimental ruminal lactic acidosis and supplemented with monensin sodium

2020 ◽  
Vol 3 (1) ◽  
pp. 7-17
Author(s):  
Ana Clara Sarzedas Ribeiro ◽  
◽  
Gliére Silmara Leite Soares ◽  
Saulo de Tarso Gusmão da Silva ◽  
Eldinê Gomes de Miranda Neto ◽  
...  
Keyword(s):  
Lactic Acidosis ◽  
Cardiac Biomarkers

Cardiac biomarkers in goats with experimental ruminal lactic acidosis and supplemented with monensin sodium

2020 ◽  
Vol 3 (1) ◽  
pp. 7-16
Author(s):  
Ana Clara Sarzedas Ribeiro ◽  
Gliére Silmara Leite Soares ◽  
Saulo de Tarso Gusmão da Silva ◽  
Eldinê Gomes de Miranda Neto ◽  
Rebeka Menezes Pontes ◽  
...  
Keyword(s):  
Lactic Acidosis ◽  
Cardiac Biomarkers
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