scholarly journals Quantum dot probes for cellular analysis

2017 ◽  
Vol 9 (18) ◽  
pp. 2621-2632 ◽  
Author(s):  
Dahai Ren ◽  
Bin Wang ◽  
Chen Hu ◽  
Zheng You
Keyword(s):  
Quantum Dots ◽  
Quantum Dot ◽  
Semiconductor Nanocrystals ◽  
Pivotal Role ◽  
Biological Applications ◽  
Cellular Analysis

Highly fluorescent and robust semiconductor nanocrystals (known as quantum dots or QDs) play a pivotal role in biological applications.

Quantum Dot-Sensitized Solar Cells via Integrated Experimental and Modeling Study

2019 ◽  
Vol 16 (2) ◽  
pp. 436-440
Author(s):  
Lekshmi Gangadhar ◽  
Anusha Kannan ◽  
P. K. Praseetha
Keyword(s):  
Quantum Dots ◽  
Solar Cells ◽  
Solar Cell ◽  
Quantum Dot ◽  
Low Cost ◽  
Semiconductor Nanocrystals ◽  
Green Energy ◽  
Research Areas ◽  
Sensitized Solar Cells ◽  
Modeling Study

The solar energy is one of the potential renewable green energy source considering the availability of sunlight in abundance and the need for clean and renewable source of energy. Quantum dots are semiconductor nanocrystals having considerable interest in photovoltaic research areas. Cadmium sulfide-sensitized solar cells are synthesized by Chemical bath deposition and titanium nanowires were fabricated by hydrothermal method. The synthesized CdS quantum dots are sensitized to nanoporous TiO2 films to form quantum dots-sensitized solar cell applications. The introduction of TNWs enables the electrolyte to penetrate easily inside the film which increases the interfacial contact between the nanowires, the quantum dots and the electrolyte results in improvement in efficiency of solar cell. The goal of our research is to understand the fundamental physics and performance of quantum dot-sensitized solar cells with improved photoconversion efficiency at the low cost based on selection of TiO2 nanostructures, sensitizers and electrodes through an integrated experimental and modeling study.

scholarly journals Synthesis, Characterization and Evaluation of the Cytotoxicity of Ni-Doped Zn(Se,S) Quantum Dots

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Melissa Cruz-Acuña ◽  
Sonia Bailón-Ruiz ◽  
Carlos R. Marti-Figueroa ◽  
Ricardo Cruz-Acuña ◽  
Oscar J. Perales-Pérez
Keyword(s):  
Drug Delivery ◽  
Quantum Dots ◽  
Optical Properties ◽  
Cell Viability ◽  
Zinc Chloride ◽  
Semiconductor Nanocrystals ◽  
Carcinoma Cells ◽  
Biological Applications ◽  
Potential Toxicity ◽  
Light Excitation

Quantum dots (QDs) are semiconductor nanocrystals with desirable optical properties for biological applications, such as bioimaging and drug delivery. However, the potential toxicity of these nanostructures in biological systems limits their application. The present work is focused on the synthesis, characterization, and evaluation of the toxicity of water-stable Ni-doped Zn(Se,S) QDs. Also, the study of nondoped nanostructures was included for comparison purposes. Ni-doped nanostructures were produced from zinc chloride and selenide aqueous solutions in presence of 3-mercaptopropionic acid and Ni molar concentration of 0.001 M. In order to evaluate the potential cytoxicity of these doped nanostructures, human pancreatic carcinoma cells (PANC-1) were used as model. The cell viability was monitored in presence of Ni-doped Zn(Se,S) QDs at concentrations ranging from 0 μg/mL to 500 μg/mL and light excited Ni-doped Zn(Se,S) nanostructures were evaluated at 50 μg/mL. Results suggested that Ni-doped Zn(Se,S) nanostructures were completely safe to PANC-1 when concentrations from 0 μg/mL to 500 μg/mL were used, whereas non-doped nanostructures evidenced toxicity at concentrations higher than 200 μg/mL. Also, Ni-doped Zn(Se,S) QDs under light excitation do not evidence toxicity to PANC-1. These findings suggest strongly that Zn(Se,S) nanostructures doped with nickel could be used in a safe manner in light-driving biological applications and drug delivery.

Synthesis and Application of Quantum Dot-Tagged Fluorescent Microbeads

2008 ◽  
Vol 8 (3) ◽  
pp. 1138-1149 ◽  
Author(s):  
Qiang Ma ◽  
Chao Wang ◽  
Xingguang Su
Keyword(s):  
Quantum Dots ◽  
Surface Modification ◽  
Quantum Dot ◽  
Biological Applications ◽  
Fluorescent Labels ◽  
Biological Detection ◽  
New Class ◽  
Fluorescent Microbeads

Fluorescent quantum dots have been used in biological applications as desirable fluorescent labels instead of traditional fluorophores. Incorporation into microspheres enhances many features of quantum dots that make them ideal for biological detection, such as photostability, multi-target, and improved brightness. Quantum dot-tagged microbeads are emerging as a new class of fluorescent labels and are expected to open new opportunities in nanotechnology and biology. In this review, we describe different approaches for the synthesis of quantum dot-tagged microbeads, surface modification methods that make microbeads suitable for bioconjugation, and the biological applications of the quantum dot-tagged fluorescent microbeads with their desired features in recent research. We also discuss the limitations of some kinds of quantum dot-tagged microbeads and the developments that will enhance their abilities in biological applications.

Biocompatible Polymeric Nanoparticles and Films Containing Hydrophobic Quantum Dots

2006 ◽  
Vol 950 ◽  
Author(s):  
Jisook Lee ◽  
Ick Chan Kwon ◽  
Kyoungja Woo ◽  
Hesson Chung
Keyword(s):  
Quantum Dots ◽  
Quantum Dot ◽  
Tumor Cells ◽  
Polymeric Nanoparticles ◽  
Aqueous Media ◽  
Nano Particles ◽  
Film Casting ◽  
Biological Applications ◽  
Stable Particles ◽  
Nih 3T3

ABSTRACTMicro- or nano-particles encapsulating hydrophobic quantum dots were prepared by the emulsion technique. Films containing quantum dots were also prepared by film casting methods. Quantum dots without hydrophilic coating were directly mixed with polymer solution to prepared extremely stable films or particles that do not phase-separate with time. The surface of the particles or films could be modified to have different hydrophilicity and/or functional groups. Particles with 1.5 ± 0.16 μm and 320 ± 26 nm in diameters and films of 300 μm in thickness were prepared. NIH 3T3 and EMT-6 were culture on the films containing quantum dots for 8 – 20 h. Compared to the control, quantum dot were delivered directly and efficiently into the cells without toxicity. When implanted near tumor cells in Balb/C mice, quantum dots migrated from the films into the tumor cells for at least 3 days. Considering that the quantum dot dispersion in aqueous media is relatively unstable and difficult to handle, our stable particles or films containing hydrophobic quantum dots can become versatile probes for biological applications.

Assessing the Environmental Effects Related to Quantum Dot Structure, Function, Synthesis and Exposure

2021 ◽  
Author(s):  
Marissa Giroux ◽  
Zahra Zahra ◽  
Omobayo Adio Salawu ◽  
Robert M. Burgess ◽  
Kay T. Ho ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Quantum Yield ◽  
Quantum Dot ◽  
Structure Function ◽  
Environmental Effects ◽  
Quantum Confinement ◽  
Semiconductor Nanocrystals

Quantum dots (QDs) are engineered semiconductor nanocrystals with unique fluorescent, quantum confinement, and quantum yield properties, making them valuable in a range of commercial and consumer imaging, display, and lighting...

An antibody-conjugated internalizing quantum dot suitable for long-term live imaging of cells

2007 ◽  
Vol 85 (1) ◽  
pp. 133-140 ◽  
Author(s):  
Zeenia Kaul ◽  
Tomoko Yaguchi ◽  
Jun I. Harada ◽  
Yutaka Ikeda ◽  
Takashi Hirano ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Molecular Imaging ◽  
Fluorescent Dyes ◽  
Organic Dyes ◽  
Semiconductor Nanocrystals ◽  
Biological Applications ◽  
Therapeutic Tool ◽  
Sensitive Tool ◽  
Antibody Conjugate

Quantum dots (QD) are fluorescent semiconductor nanocrystals that are emerging as superior alternatives to the conventional organic dyes used in biological applications. Although QDs offer several advantages over conventional fluorescent dyes, including greater photostability and a wider range of excitation and (or) emission wavelengths, their toxicity has been an issue in its wider use as an analytic, diagnostic and therapeutic tool. We prepared a conjugate QD with an internalizing antibody and demonstrated that the QD–antibody conjugate is efficiently internalized into cells and is visible even after multiple divisions. We demonstrate that the internalized QD is nontoxic to cells and provides a sensitive tool for long-term molecular imaging.

scholarly journals A novel pollen-tracking method: using quantum dots as pollen labels

2018 ◽  
Author(s):  
Corneile Minnaar ◽  
Bruce Anderson
Keyword(s):  
Quantum Dots ◽  
Oleic Acid ◽  
Quantum Dot ◽  
Uv Light ◽  
Semiconductor Nanocrystals ◽  
Bright Light ◽  
Pollen Grains ◽  
Pollen Grain ◽  
Pollen Transport ◽  
History Of

ABSTRACTTo understand the evolution of flowers and mating systems in animal-pollinated plants, we have to directly address the function for which flowers evolved—the movement of pollen from anthers to stigmas. However, despite a long history of making significant advances in our understanding natural selection and evolution, the field of pollination biology has largely studied pollen movement indirectly (e.g., pollen analogues or paternity assignment to seeds) due to a lack of suitable pollen tracking methods. Here, we develop and test a novel pollen-tracking technique using quantum dots as pollen-grain labels. Quantum dots are semiconductor nanocrystals so small in size that they behave like artificial atoms. When exposed to UV light, they emit extremely bright light in a range of different colours. Their photostability, broad excitation range, and customisable binding-li-gands make quantum dots ideal bio-labels. We tested the suitability of CuInSexS2-x/ZnS (core/shell) quantum dots with oleic acid (zinc-oleate complex) ligands as pollen-grain labels. We found that quantum dots attach to pollen grains of four different species even after agitation in a polar solvent, suggesting that the oleic acid ligands on quantum dots bind to pollenkitt surrounding pollen grains. We also showed that most pollen grains within anthers of the same four species are labelled with quantum dots after applying sufficient quantum-dot solution to anthers. To test whether quantum-dot pollen-labels influenced pollen transport, we conducted pollen transfer trials on Sparaxis villosa (Iridaceae) using captively reared honeybees. We found no difference in pollen transport between labelled and unlabelled pollen grains. Our experiments therefore demonstrate the potential for quantum dots to be used as easily applied pollen labels, which allow subsequent tracking of the fates of pollen grains in the field. The ability to track pollen grain movement in situ, may finally allow us to address an historically neglected aspect of plant reproductive ecology and evolution.

Comparative cradle-to-gate energy assessment of indium phosphide and cadmium selenide quantum dot displays

2017 ◽  
Vol 4 (1) ◽  
pp. 244-254 ◽  
Author(s):  
Shauhrat S. Chopra ◽  
Thomas L. Theis
Keyword(s):  
Quantum Dots ◽  
Quantum Dot ◽  
Indium Phosphide ◽  
Cadmium Selenide ◽  
Semiconductor Nanocrystals ◽  
Band Gaps ◽  
Luminescence Properties ◽  
Energy Assessment ◽  
Cradle To Gate

Quantum dots (QDs) are semiconductor nanocrystals (2–10 nm) with tunable band gaps and desirable luminescence properties.

Preparation of Graphene Quantum Dots and Their Biological Applications

2016 ◽  
Vol 31 (4) ◽  
pp. 337 ◽  
Author(s):  
SUN Xiao-Dan ◽  
LIU Zhong-Qun ◽  
YAN Hao
Keyword(s):  
Quantum Dots ◽  
Graphene Quantum Dots ◽  
Biological Applications

NiAg-graphene quantum dot-graphene hybrid with high oxidase-like catalytic activity for sensitive colorimetric detection of malathion

2021 ◽  
Author(s):  
Xu Dan ◽  
Ruiyi Li ◽  
Qinsheng Wang ◽  
Yongqiang Yang ◽  
Haiyan Zhu ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Graphene Oxide ◽  
Catalytic Activity ◽  
Quantum Dot ◽  
Colorimetric Detection ◽  
Graphene Quantum Dots ◽  
Functionalized Graphene ◽  
Graphene Quantum Dot ◽  
Nickel Silver

The paper reports the synthesis of nickel-silver-graphene quantum dot-graphene hybrid. Histidine-functionalized graphene quantum dots (His-GQDs) were bonded to graphene oxide (GO) and then combined with Ni2+ and Ag+ to form...

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