scholarly journals Development of a BALB/c mouse model for food allergy: comparison of allergy-related responses to peanut agglutinin, β-lactoglobulin and potato acid phosphatase

2017 ◽  
Vol 6 (2) ◽  
pp. 251-261 ◽  
Author(s):  
Chen Chen ◽  
Lu Lianhua ◽  
Sun Nana ◽  
Li Yongning ◽  
Jia Xudong
Keyword(s):  
Food Allergy ◽  
Acid Phosphatase ◽  
Mouse Model ◽  
Peanut Agglutinin ◽  
Β Lactoglobulin

Histopathology results of ear segments in mice (sensitized with 0.05 mg and 0 protein) i.p. and i.g. challenged with the corresponding proteins are shown below.

Anti-allergenic effects of peanut sprouts extract in a systemic anaphylaxis food allergy mouse model

2019 ◽  
Author(s):  
WK Yang ◽  
DS Kim ◽  
E Son ◽  
YM Lee ◽  
DS Lee ◽  
...  
Keyword(s):  
Food Allergy ◽  
Mouse Model ◽  
Systemic Anaphylaxis

Therapeutic Effect of Kakkonto in a Mouse Model of Food Allergy with Gastrointestinal Symptoms

2009 ◽  
Vol 148 (3) ◽  
pp. 175-185 ◽  
Author(s):  
Takeshi Yamamoto ◽  
Kanae Fujiwara ◽  
Minako Yoshida ◽  
Natsuko Kageyama-Yahara ◽  
Hirofumi Kuramoto ◽  
...  
Keyword(s):  
Food Allergy ◽  
Mouse Model ◽  
Therapeutic Effect ◽  
Gastrointestinal Symptoms

scholarly journals Gastric Enzyme Supplementation Inhibits Food Allergy in a BALB/c Mouse Model

Nutrients ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 738
Author(s):  
Nazanin Samadi ◽  
Denise Heiden ◽  
Martina Klems ◽  
Martina Salzmann ◽  
Johanna Rohrhofer ◽  
...  
Keyword(s):  
Food Allergy ◽  
Mouse Model ◽  
Gastric Acid ◽  
Clinical Symptoms ◽  
Acid Suppression ◽  
Gastric Digestion ◽  
Enzyme Solution ◽  
Allergic Symptoms ◽  
Gastric Acid Suppression ◽  
The Impact

Impaired gastric digestion due to suppressed gastric acidity enhances the risk for food allergy development. In the current study, we aimed to evaluate the impact of a supported gastric digestion via application of a pharmaceutical gastric enzyme solution (GES) on food allergy development and allergic reactions in a BALB/c mouse model. The ability of the GES to restore hypoacidic conditions was tested in mice treated with gastric acid suppression medication. To evaluate the impact on allergic symptoms, mice were orally sensitized with ovalbumin (OVA) under gastric acid suppression and subjected to oral challenges with or without GES. The immune response was evaluated by measurement of antibody titers, cytokine levels, mucosal allergy effector cell influx and regulatory T-cell counts. Clinical response was objectified by core body temperature measurements after oral OVA challenge. Supplementation of GES transiently restored physiological pH levels in the stomach after pharmaceutical gastric acid suppression. During oral sensitization, supplementation of gastric enzymes significantly reduced systemic IgE, IgG1 and IgG2a levels and allergic symptoms. In food allergic mice, clinical symptoms were reduced by co-administration of the gastric enzyme solution. Support of gastric digestion efficiently prevents food allergy induction and alleviates clinical symptoms in our food allergy model.

Study on alleviation effect of stachyose on food allergy through TLR2/NF-κB signal pathway in a mouse model

Life Sciences ◽  
2021 ◽  
pp. 120038
Author(s):  
Qian Li ◽  
Xinlei Tang ◽  
Jianghao Xu ◽  
Xingyuan Ren ◽  
Rui Wang ◽  
...  
Keyword(s):  
Food Allergy ◽  
Mouse Model ◽  
Signal Pathway

scholarly journals Structural changes induced by heating affect ovalbumin-antigen processing and reduce allergic response in mouse model of food allergy

2014 ◽  
Vol 4 (S2) ◽  
Author(s):  
Jaroslav Goliáš ◽  
Martin Schwarzer ◽  
Hana Kozáková ◽  
Dagmar Šrùtková ◽  
Ludmila Tuèková
Keyword(s):  
Food Allergy ◽  
Mouse Model ◽  
Antigen Processing ◽  
Structural Changes ◽  
Allergic Response

Turmeric (Curcuma longa) attenuates food allergy symptoms by regulating type 1/type 2 helper T cells (Th1/Th2) balance in a mouse model of food allergy

2015 ◽  
Vol 175 ◽  
pp. 21-29 ◽  
Author(s):  
Hee Soon Shin ◽  
Hye-Jeong See ◽  
Sun Young Jung ◽  
Dae Woon Choi ◽  
Da-Ae Kwon ◽  
...  
Keyword(s):  
T Cells ◽  
Food Allergy ◽  
Mouse Model ◽  
Curcuma Longa ◽  
Helper T Cells

Antigen-specific T cell–mediated apoptosis of dendritic cells is impaired in a mouse model of food allergy☆

2004 ◽  
Vol 113 (5) ◽  
pp. 965-972 ◽  
Author(s):  
Angela L. Man ◽  
Eugenio Bertelli ◽  
Mari Regoli ◽  
Stephen J. Chambers ◽  
Claudio Nicoletti
Keyword(s):  
Dendritic Cells ◽  
Food Allergy ◽  
T Cell ◽  
Mouse Model
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