scholarly journals A universal fluorogenic switch for Fe(ii) ion based on N-oxide chemistry permits the visualization of intracellular redox equilibrium shift towards labile iron in hypoxic tumor cells

2017 ◽  
Vol 8 (7) ◽  
pp. 4858-4866 ◽  
Author(s):  
Tasuku Hirayama ◽  
Hitomi Tsuboi ◽  
Masato Niwa ◽  
Ayaji Miki ◽  
Satoki Kadota ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Fluorescent Probe ◽  
Redox Equilibrium ◽  
Hypoxic Tumor ◽  
Equilibrium Shift ◽  
Labile Iron ◽  
Intracellular Redox

Oxygen-dependent fluctuation of labile Fe(ii) was visualized by a new N-oxide-based fluorescent probe for Fe(ii) ion.

A cyanine-derived “turn-on” fluorescent probe for imaging nitroreductase in hypoxic tumor cells

2015 ◽  
Vol 7 (24) ◽  
pp. 10125-10128 ◽  
Author(s):  
Cong Xue ◽  
Yingjie Lei ◽  
Sichun Zhang ◽  
Yaowu Sha
Keyword(s):  
Tumor Cells ◽  
Fluorescent Probe ◽  
Phenol Group ◽  
Turn On ◽  
Hypoxic Tumor

A new “turn-on” fluorescent probe, composed of a protected phenol group with ap-nitrobenzyl moiety that functions as a latent donor and conjugated with two benzo[f]indolinium acceptors, was developed and applied for imaging nitroreductase (NTR) in hypoxic tumor cells.

A rapid response “Turn-On” fluorescent probe for nitroreductase detection and its application in hypoxic tumor cell imaging

The Analyst ◽  
2015 ◽  
Vol 140 (2) ◽  
pp. 574-581 ◽  
Author(s):  
Jian Xu ◽  
Shaobo Sun ◽  
Qian Li ◽  
Ying Yue ◽  
Yingdong Li ◽  
...  
Keyword(s):  
Tumor Cell ◽  
Tumor Cells ◽  
Fluorescent Probe ◽  
Cell Imaging ◽  
Rapid Response ◽  
Indirect Detection ◽  
Turn On ◽  
Hypoxic Tumor

A novel “Turn-On” fluorescent probe, quaternarized 4-pyridinyl-substituted BODIPY dye by incorporating a 5-nitrofuran moiety, was developed and applied for imaging the hypoxic status of tumor cells by the indirect detection of nitroreductase.

A fluorescent turn-on probe for visualizing lysosomes in hypoxic tumor cells

The Analyst ◽  
2016 ◽  
Vol 141 (10) ◽  
pp. 2879-2882 ◽  
Author(s):  
Sihang Luo ◽  
Yingchao Liu ◽  
Feiyi Wang ◽  
Qiang Fei ◽  
Ben Shi ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Tumor Cells ◽  
Fluorescent Probe ◽  
Reductive Cleavage ◽  
Strong Fluorescence ◽  
Turn On ◽  
Hypoxic Tumor

A fluorescent probe localized in lysosomes after reductive cleavage with azoreductase gave strong fluorescence, providing specificity for imaging lysosomes in hypoxic cancer cells.

scholarly journals Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice

2008 ◽  
Author(s):  
Pierre Sonveaux ◽  
Frédérique Végran ◽  
Thies Schroeder ◽  
Melanie C. Wergin ◽  
Julien Verrax ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Hypoxic Tumor

A melatonin-based targetable fluorescent probe activated by hydrogen peroxide for tumor cells screening

2021 ◽  
pp. 131051
Author(s):  
Xiwei Li ◽  
Na Gao ◽  
Caiyun Liu ◽  
Miaohui Yu ◽  
Xiaodi Rong ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Tumor Cells ◽  
Fluorescent Probe

911: Molecular mechanisms of the antineoplastic action of erufosine in hypoxic tumor cells

2014 ◽  
Vol 50 ◽  
pp. S223
Author(s):  
H. Riffkin ◽  
S. Oeck ◽  
G. Renzelman ◽  
R. Handrick ◽  
V. Jendrossek
Keyword(s):  
Tumor Cells ◽  
Molecular Mechanisms ◽  
Antineoplastic Action ◽  
Hypoxic Tumor

δ-Tocotrienol treatment is more effective against hypoxic tumor cells than normoxic cells: potential implications for cancer therapy

2015 ◽  
Vol 26 (8) ◽  
pp. 832-840 ◽  
Author(s):  
Akira Shibata ◽  
Kiyotaka Nakagawa ◽  
Tsuyoshi Tsuduki ◽  
Teruo Miyazawa
Keyword(s):  
Cancer Therapy ◽  
Tumor Cells ◽  
Hypoxic Tumor

scholarly journals Se-methylselenocysteine sensitizes hypoxic tumor cells to irinotecan by targeting hypoxia-inducible factor 1α

2010 ◽  
Vol 66 (5) ◽  
pp. 899-911 ◽  
Author(s):  
Sreenivasulu Chintala ◽  
Károly Tόth ◽  
Shousong Cao ◽  
Farukh A. Durrani ◽  
Mary M. Vaughan ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Hypoxia Inducible Factor ◽  
Hypoxia Inducible Factor 1Α ◽  
Hypoxic Tumor
Sign in / Sign up

Export Citation Format

Share Document