scholarly journals Fluorescent silver nanoparticle based highly sensitive immunoassay for early detection of HIV infection

RSC Advances ◽  
2017 ◽  
Vol 7 (32) ◽  
pp. 19863-19877 ◽  
Author(s):  
Aditya Dileep Kurdekar ◽  
L. A. Avinash Chunduri ◽  
Sai Manohar Chelli ◽  
Mohan Kumar Haleyurgirisetty ◽  
Eswarappa Pradeep Bulagonda ◽  
...  

Fluorescent silver nanoparticles have been employed in an immunoassay to detect HIV p24 antigen with high sensitivity in the linear range of 10–1000 pg mL−1.

1993 ◽  
Vol 328 (5) ◽  
pp. 297-302 ◽  
Author(s):  
Steven A. Miles ◽  
Erin Balden ◽  
Larry Magpantay ◽  
LeAnn Wei ◽  
Alison Leiblein ◽  
...  

Nanomaterials ◽  
2019 ◽  
Vol 9 (3) ◽  
pp. 384 ◽  
Author(s):  
Zhiliang Zhang ◽  
Tiantian Si ◽  
Jun Liu ◽  
Guowei Zhou

The rapid sampling and efficient collection of target molecules from a real-world surface is fairly crucial for surface-enhanced Raman scattering (SERS) to detect trace pesticide residues in the environment and in agriculture fields. In this work, a versatile approach was exploited to fabricate a flexible SERS substrate for highly sensitive detection of carbaryl pesticides, using in-situ grown silver nanoparticles (AgNPs)on non-woven (NW) fabric surfaces based on mussel-inspired polydopamine (PDA) molecules. The obtained NW@PDA@AgNPs fabrics showed extremely sensitive and reproducible SERS signals toward crystal violet (CV) molecules, and the detection limit was as low as 1.0 × 10−12 M. More importantly, these NW@PDA@AgNPs fabrics could be directly utilized as flexible SERS substrates for the rapid extraction and detection of trace carbaryl pesticides from various fruit surfaces through a simple swabbing approach. It was identified that the detection limits of carbaryl residues from apple, orange, and banana surfaces were approximately decreased to 4.02 × 10−12, 6.04 × 10−12, and 5.03 × 10−12 g, respectively, demonstrating high sensitivity and superior reliability. These flexible substrates could not only drastically increase the collection efficiency from multifarious irregular-shaped matrices, but also greatly enhance analytical sensitivity and reliability for carbaryl pesticides. The fabricated flexible and multifunctional SERS substrates would have great potential to trace pesticide residue detection in the environment and bioscience fields.


1993 ◽  
Vol 42 (3) ◽  
pp. 322-323
Author(s):  
S.A. Miles ◽  
E. Balden ◽  
L. Magpantay ◽  
L. Wei ◽  
A. Leiblein ◽  
...  

2017 ◽  
Author(s):  
Hossein Zare ◽  
Ghasem Najafpour ◽  
Mohsen Jahanshahi ◽  
Mostafa Rahimnejad ◽  
Mohsen Rezvani

A highly sensitive biosensor based on silver nanoparticles (AgNPs) was fabricated for glucose detection in aqueous phase. Firstly, a platinum (Pt) electrode was modified with the mixture of glucose oxidase and chitosan. AgNPs were electrodeposited into the modified electrode by single pulse potentiostatic method at –0.4 V. The electrochemical performance of the modified electrode was evaluated by cyclic voltammetry and amperometry. The fabricated biosensor had a high sensitivity of 58.6 μA mM−1 cm−2 and detection limit of 4.4 μM glucose at a signal to noise ratio of 3. In addition, the biosensor showed a short response time less than 5 s and a wide linear range of 0.05-11.5 mM. The apparent Michaelis–Menten constant (KM) was found to be 9.14 mM. In addition, thermal stability and anti-interference ability of the biosensor were investigated. The results demonstrated that AgNPs enhanced the analytical performance of the biosensor.


RSC Advances ◽  
2019 ◽  
Vol 9 (68) ◽  
pp. 39958-39964
Author(s):  
Xinxiu Wu ◽  
Fangfang Niu ◽  
Ao Zhong ◽  
Fei Han ◽  
Yun Chen ◽  
...  

Silver nanoparticle-decorated three-dimensional graphene foams were prepared and packaged with half-cured PMDS films, forming a special “hollow packaged” structure that exhibited high sensitivity for wearable strain sensor applications.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Siwar Jebril ◽  
Alaeddine Fdhila ◽  
Chérif Dridi

AbstractThe production of environmentally friendly silver nanoparticles (AgNPs) has aroused the interest of the scientific community due to their wide applications mainly in the field of environmental pollution detection and water quality monitoring. Here, for the first time, five plant leaf extracts were used for the synthesis of AgNPs such as Basil, Geranium, Eucalyptus, Melia, and Ruta by a simple and eco-friendly method. Stable AgNPs were obtained by adding a silver nitrate (AgNO3) solution with the leaves extract as reducers, stabilizers and cappers. Only, within ten minutes of reaction, the yellow mixture changed to brown due to the reduction of Ag+ ions to Ag atoms. The optical, structural, and morphology characteristics of synthesized AgNPs were determined using a full technique like UV–visible spectroscopy, FTIR spectrum, XRD, EDX spectroscopy, and the SEM. Thus, Melia azedarach was found to exhibit smaller nanoparticles (AgNPs-M), which would be interesting for electrochemical application. So, a highly sensitive electrochemical sensor based on AgNPs-M modified GCE for phenol determination in water samples was developed, indicating that the AgNPs-M displayed good electrocatalytic activity. The developed sensor showed good sensing performances: a high sensitivity, a low LOD of 0.42 µM and good stability with a lifetime of about one month, as well as a good selectivity towards BPA and CC (with a deviation less than 10%) especially for nanoplastics analysis in the water contained in plastics bottles. The obtained results are repeatable and reproducible with RSDs of 5.49% and 3.18% respectively. Besides, our developed sensor was successfully applied for the determination of phenol in tap and mineral water samples. The proposed new approach is highly recommended to develop a simple, cost effective, ecofriendly, and highly sensitive sensor for the electrochemical detection of phenol which can further broaden the applications of green silver NPs.


RSC Advances ◽  
2015 ◽  
Vol 5 (52) ◽  
pp. 41595-41603 ◽  
Author(s):  
Lokesh Shastri ◽  
Hani Nasser Abdelhamid ◽  
Mohd Nawaz ◽  
Hui-Fen Wu

Synthesis, characterization and bifunctional applications of silver nanoparticles with two different surface capping reagents are reported.


2014 ◽  
Vol 38 (12) ◽  
pp. 5873-5879 ◽  
Author(s):  
Ahmad Umar ◽  
Rafiq Ahmad ◽  
Ali Al-Hajry ◽  
Sang Hoon Kim ◽  
Mohamed Eisa Abaker ◽  
...  

A highly sensitive and selective amperometric glucose biosensor based on spruce branched α-Fe2O3 nanostructures exhibited high sensitivity over a wide linear range.


NANO ◽  
2017 ◽  
Vol 12 (07) ◽  
pp. 1750090
Author(s):  
Na Li ◽  
Yaoyong Meng ◽  
Yongfang Dong ◽  
Zhiyou Guo ◽  
Nan Li

A system for the highly sensitive detection of Pb[Formula: see text] ions by surface-enhanced Raman scattering (SERS) was designed based on silver nanoparticles (AgNPs) capped with iminodiacetic acid (IDA)/4-mercaptopyridine (4-MPY). In this system, IDA was absorbed on the surface of the AgNPs to induce the coupling of Pb[Formula: see text] ions for aggregation in the aqueous solution. 4-MPY, which was also attached to the surface of the AgNPs, was used as a Raman reporter. When the concentration of Pb[Formula: see text] ions increased, a stronger 4-MPY Raman signal was detected. The IDA and 4-MPY concentrations were adjusted to maximize the 4-MPY Raman signal. Under this optimal condition, the concentration of Pb[Formula: see text] ions had a linear relationship with 4-MPY Raman signal in the range of 1[Formula: see text][Formula: see text][Formula: see text]108 to [Formula: see text][Formula: see text]mol/L ([Formula: see text]). The limit of detection (LOD) of 1.816[Formula: see text]nmol/L was obtained, which is significantly lower than the World Health Organization’s (WHO) defined limit of 100[Formula: see text][Formula: see text]g/L in drinking water. This system was successfully applied to determine the Pb[Formula: see text] concentration in a contaminated water sample, which is obtained by adding a trace of Pb[Formula: see text] ions to drinking mineral water. The results proved that the IDA/4-MPY-modified AgNPs sensing system had a potential application for the Pb[Formula: see text] measurement with high sensitivity and excellent selectivity.


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