scholarly journals Evaluation of a chloroaluminium phthalocyanine-loaded magnetic nanoemulsion as a drug delivery device to treat glioblastoma using hyperthermia and photodynamic therapy

RSC Advances ◽  
2017 ◽  
Vol 7 (15) ◽  
pp. 9115-9122 ◽  
Author(s):  
L. B. de Paula ◽  
F. L. Primo ◽  
M. R. Pinto ◽  
P. C. Morais ◽  
A. C. Tedesco
Keyword(s):  
Drug Delivery ◽  
Photodynamic Therapy ◽  
Cell Lines ◽  
Maghemite Nanoparticles ◽  
Delivery Device ◽  
Drug Delivery Device

The study describes the development of magnetic nanoemulsion loaded with citrate-coated maghemite nanoparticles and photosensitizer and the in vitro studies using cell lines while combining the use of hyperthermia and photodynamic therapy therapies.

DC Bead: In Vitro Characterization of a Drug-delivery Device for Transarterial Chemoembolization

2006 ◽  
Vol 17 (2) ◽  
pp. 335-342 ◽  
Author(s):  
Andrew L. Lewis ◽  
M. Victoria Gonzalez ◽  
Andrew W. Lloyd ◽  
Brenda Hall ◽  
Yiqing Tang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Transarterial Chemoembolization ◽  
Delivery Device ◽  
Drug Delivery Device ◽  
In Vitro Characterization

In Vitro–In Vivo Evaluation of an Oral Ghost Drug Delivery Device for the Delivery of Salmon Calcitonin

2018 ◽  
Vol 107 (6) ◽  
pp. 1605-1614 ◽  
Author(s):  
Angus R. Hibbins ◽  
Mershen Govender ◽  
Sunaina Indermun ◽  
Pradeep Kumar ◽  
Lisa C. du Toit ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Salmon Calcitonin ◽  
Delivery Device ◽  
In Vivo Evaluation ◽  
Drug Delivery Device

scholarly journals Design and in Vitro Biocompatibility of a Novel Ocular Drug Delivery Device

2013 ◽  
Vol 4 (1) ◽  
pp. 14-26 ◽  
Author(s):  
Nathan Gooch ◽  
Randon Burr ◽  
Dolly Holt ◽  
Bruce Gale ◽  
Balamurali Ambati
Keyword(s):  
Drug Delivery ◽  
Ocular Drug Delivery ◽  
Delivery Device ◽  
Drug Delivery Device ◽  
In Vitro Biocompatibility

scholarly journals A 3D Printed Self-Sustainable Cell-Encapsulation Drug Delivery Device for Periocular Transplant-Based Treatment of Retinal Degenerative Diseases

Micromachines ◽  
2020 ◽  
Vol 11 (4) ◽  
pp. 436 ◽  
Author(s):  
Hideto Kojima ◽  
Bibek Raut ◽  
Li-Jiun Chen ◽  
Nobuhiro Nagai ◽  
Toshiaki Abe ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Minimally Invasive ◽  
Retinal Pigment ◽  
Cell Encapsulation ◽  
Degenerative Diseases ◽  
Delivery Device ◽  
Drug Delivery Device ◽  
3D Printed ◽  
Retinal Degenerative Diseases

Self-sustainable release of brain-derived neurotrophic factor (BDNF) to the retina using minimally invasive cell-encapsulation devices is a promising approach to treat retinal degenerative diseases (RDD). Herein, we describe such a self-sustainable drug delivery device with human retinal pigment epithelial (ARPE-19) cells (cultured on collagen coated polystyrene (PS) sheets) enclosed inside a 3D printed semi-porous capsule. The capsule was 3D printed with two photo curable polymers: triethylene glycol dimethacrylate (TEGDM) and polyethylene glycol dimethylacrylate (PEGDM). The capsule’s semi-porous membrane (PEGDM) could serve three functions: protecting the cells from body’s immune system by limiting diffusion (5.97 ± 0.11%) of large molecules like immunoglobin G (IgG)(150 kDa); helping the cells to survive inside the capsule by allowing diffusion (43.20 ± 2.16%) of small molecules (40 kDa) like oxygen and necessary nutrients; and helping in the treatment of RDD by allowing diffusion of cell-secreted BDNF to the outside environment. In vitro results showed a continuous BDNF secretion from the device for at least 16 days, demonstrating future potential of the cell-encapsulation device for the treatment of RDD in a minimally invasive and self-sustainable way through a periocular transplant.

scholarly journals Novel Drug Delivery Device Using Silicone: Controlled Release of Insoluble Drugs or Two Kinds of Water-Soluble Drugs

2003 ◽  
Vol 51 (1) ◽  
pp. 15-19 ◽  
Author(s):  
Masako Kajihara ◽  
Toshihiko Sugie ◽  
Hiroo Maeda ◽  
Akihiko Sano ◽  
Keiji Fujioka ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Controlled Release ◽  
Water Soluble ◽  
Delivery Device ◽  
Drug Delivery Device ◽  
Water Soluble Drugs ◽  
Insoluble Drugs ◽  
Novel Drug
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