scholarly journals Controlled release of vancomycin from 3D porous graphene-based composites for dual-purpose treatment of infected bone defects

RSC Advances ◽  
2017 ◽  
Vol 7 (5) ◽  
pp. 2753-2765 ◽  
Author(s):  
Weizong Weng ◽  
Wei Nie ◽  
Qirong Zhou ◽  
Xiaojun Zhou ◽  
Liehu Cao ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Controlled Release ◽  
Bone Regeneration ◽  
Reduced Graphene Oxide ◽  
Bone Defects ◽  
Bone Infection ◽  
Porous Composite ◽  
Dual Purpose ◽  
Porous Graphene ◽  
Reduced Graphene

A vancomycin-loaded reduced graphene oxide/nano-hydroxyapatite (RGO–nHA) 3D porous composite for eradication of bone infection and facilitation of bone regeneration.

Electro-stimulated release from a reduced graphene oxide composite hydrogel

2015 ◽  
Vol 3 (12) ◽  
pp. 2530-2537 ◽  
Author(s):  
Nicky Mac Kenna ◽  
Paul Calvert ◽  
Aoife Morrin ◽  
Gordon G. Wallace ◽  
Simon E. Moulton
Keyword(s):  
Graphene Oxide ◽  
Controlled Release ◽  
Reduced Graphene Oxide ◽  
Composite Hydrogel ◽  
Oxide Composite ◽  
Reduced Graphene

Composite hydrogel containing reduced graphene oxide (rGO) demonstrating the ability to perform electro-stimulated controlled release.

Three-dimensional porous graphene/polyaniline composites for high-rate electrochemical capacitors

2014 ◽  
Vol 2 (41) ◽  
pp. 17489-17494 ◽  
Author(s):  
Qinqin Zhou ◽  
Yingru Li ◽  
Liang Huang ◽  
Chun Li ◽  
Gaoquan Shi
Keyword(s):  
Graphene Oxide ◽  
Reduced Graphene Oxide ◽  
Three Dimensional ◽  
Electrochemical Capacitors ◽  
Rate Capability ◽  
High Rate ◽  
Porous Graphene ◽  
Reduced Graphene ◽  
Polyaniline Composites ◽  
Porous Composites

Three-dimensional porous composites of reduced graphene oxide and polyaniline prepared by electro-codeposition exhibited much higher areal specific capacitances and greatly improved rate capability compared with those of their individual components.

scholarly journals Oxygen Plasma Technology-Assisted Preparation of Three-Dimensional Reduced Graphene Oxide/Polypyrrole/Strontium Composite Scaffold for Repair of Bone Defects Caused by Osteoporosis

Molecules ◽  
2021 ◽  
Vol 26 (15) ◽  
pp. 4451
Author(s):  
Xiaoxue Mai ◽  
Zebiao Kang ◽  
Na Wang ◽  
Xiaoli Qin ◽  
Weibo Xie ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Graphene Oxide ◽  
Bone Tissue Engineering ◽  
Reduced Graphene Oxide ◽  
Oxygen Plasma ◽  
Composite Scaffold ◽  
Three Dimensional ◽  
Bone Defects ◽  
Plasma Technology ◽  
Reduced Graphene

Repairs of bone defects caused by osteoporosis have always relied on bone tissue engineering. However, the preparation of composite tissue engineering scaffolds with a three-dimensional (3D) macroporous structure poses huge challenges in achieving osteoconduction and osteoinduction for repairing bone defects caused by osteoporosis. In the current study, a three-dimensional macroporous (150–300 μm) reduced graphene oxide/polypyrrole composite scaffold modified by strontium (Sr) (3D rGO/PPY/Sr) was successfully prepared using the oxygen plasma technology-assisted method, which is simple, safe, and inexpensive. The findings of the MTT assay and AO/EB fluorescence double staining showed that 3D rGO/PPY/Sr has a good biocompatibility and effectively promoted MC3T3-E1 cell proliferation. Furthermore, the ALP assay and alizarin red staining showed that 3D rGO/PPY/Sr increased the expression levels of ALP activity and the formation of calcified nodules. The desirable biocompatibility, osteoconduction, and osteoinduction abilities, assure that the 3D macroporous rGO/PPY/Sr composite scaffold offers promising potential for use in the repair of bone defects caused by osteoporosis in bone tissue engineering.

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