Transferrin-conjugated paclitaxel prodrugs for targeted cancer therapy

RSC Advances ◽  
2016 ◽  
Vol 6 (81) ◽  
pp. 77987-77998 ◽  
Author(s):  
Lingling Shan ◽  
Xin Shan ◽  
Tinging Zhang ◽  
Kefeng Zhai ◽  
Guizhen Gao ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Wide Spectrum ◽  
Targeted Cancer Therapy ◽  
Chemotherapeutic Drugs

Paclitaxel (PTX) is one of the most effective chemotherapeutic drugs ever developed and is effective against a wide spectrum of tumors.

scholarly journals Chemotherapeutic, Toxin, and Therapeutic Protein Delivery via Nucleolin Aptamer-functionalized Nanoplatforms for Targeted Cancer Therapy

2021 ◽  
Vol 1 (1) ◽  
Author(s):  
Pouya Safarzadeh Kozani ◽  
Pooria Safarzadeh Kozani ◽  
Fatemeh Rahbarizadeh
Keyword(s):  
Cancer Therapy ◽  
Targeted Delivery ◽  
Protein Delivery ◽  
Therapeutic Potential ◽  
Therapeutic Protein ◽  
Targeted Cancer Therapy ◽  
Chemotherapeutic Drugs ◽  
Different Types ◽  
As1411 Aptamer ◽  
Targeting Peptide

: Nucleolin is a protein abundantly present in the nucleolus, but its expression on the surface of cells is potentially associated with various types of malignancies. So far, several nucleolin-targeting strategies, including the nucleolin-targeting peptide, anti-nucleolin pseudopeptides, anti-nucleolin antibodies, and the anti-nucleolin aptamer, AS1411, have been developed and investigated in different types of studies. The AS1411 aptamer has been known as the outstanding approach for targeting nucleolin with superior specificity and therapeutic potential in comparison with other targeting strategies. In this review, we highlight different nucleolin-targeting strategies for the targeted delivery of chemotherapeutic drugs, proteins with therapeutic potential, and toxins.

Targeted Cancer Therapy; Nanotechnology Approaches for Overcoming Drug Resistance

2015 ◽  
Vol 22 (11) ◽  
pp. 1335-1347 ◽  
Author(s):  
Yan Gao ◽  
Jacson Shen ◽  
Lara Milane ◽  
Francis Hornicek ◽  
Mansoor Amiji ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Cancer Therapy ◽  
Targeted Cancer Therapy

Biological Carrier Molecules of Radiopharmaceuticals for Molecular Cancer Imaging and Targeted Cancer Therapy

2014 ◽  
Vol 20 (32) ◽  
pp. 5218-5244 ◽  
Author(s):  
A. Aerts ◽  
N.R.E.N. Impens ◽  
M. Gijs ◽  
M. D'Huyvetter ◽  
H. Vanmarcke ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Cancer Imaging ◽  
Targeted Cancer Therapy

Exploring Nanoemulsion for Liver Cancer Therapy

2020 ◽  
Vol 16 (4) ◽  
pp. 260-268
Author(s):  
Tanmay Upadhyay ◽  
Vaseem A. Ansari ◽  
Usama Ahmad ◽  
Nazneen Sultana ◽  
Juber Akhtar
Keyword(s):  
Cancer Therapy ◽  
Liver Cancer ◽  
Treatment Plan ◽  
Chemotherapeutic Drugs ◽  
Drug Delivery Vehicles ◽  
Chronic Hepatitis B Virus ◽  
Anti Cancer ◽  
B Virus ◽  
Delivery Vehicles ◽  
Liquid Dosage Form

Cancer is a leading cause of mortality worldwide, accounting for 8.8 million deaths in 2015. Among these, at least 0.78 million people died of liver cancer alone. The recognized risk factors for liver cancer include chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infection, exposure to dietary aflatoxin, fatty liver disease, alcohol-induced cirrhosis, obesity, smoking, diabetes, and iron overload. The treatment plan for early diagnosed patients includes radiation therapy, tumour ablation, surgery, immunotherapy, and chemotherapy. Some sort of drug delivery vehicles has to be used when the treatment plan is targeted chemotherapy. Nanoemulsions are a class of biphasic liquid dosage form which are mixtures of oil and water stabilized by a surfactant. They are either transparent or bluish in hue and serve as a wonderful carrier system for chemotherapeutic drugs. These vehicles have a particle size in the range of 20-200 nm allowing them to be delivered successfully in the deepest of tissues. Recent publications on nanoemulsions reveal their acceptance and a popular choice for delivering both synthetic and herbal drugs to the liver. This work focuses on some anti-cancer agents that utilized the advantages of nanoemulsion for liver cancer therapy.

TEM8 Targeted Cancer Therapy

2011 ◽  
Vol 11 (10) ◽  
pp. 983-992 ◽  
Author(s):  
Arthur E. Frankel ◽  
Carol Carter ◽  
Shu-Ru Kuo ◽  
Jung-Hee Woo ◽  
Jeremy Mauldin ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Targeted Cancer Therapy

Novel Nanotechnology Approaches for Targeted Cancer Therapy

2014 ◽  
Vol 3 (2) ◽  
pp. 83-88 ◽  
Author(s):  
Maria Gazouli ◽  
Nikolitsa Nomikou ◽  
John F Callan ◽  
Efstathios P. Efstathopoulos
Keyword(s):  
Cancer Therapy ◽  
Targeted Cancer Therapy

Comparative radium-223 labeling with NOTA and DOTA-somatostatin derivatives for a potential use in targeted cancer therapy

2019 ◽  
Vol 72-73 ◽  
pp. S50-S51
Author(s):  
M. Riondato ◽  
S. Pastorino ◽  
V. Duce ◽  
E. Giovannini ◽  
A. Ciarmiello
Keyword(s):  
Cancer Therapy ◽  
Targeted Cancer Therapy ◽  
Radium 223 ◽  
Potential Use

Multicolor Two‐photon Nanosystem for Multiplexed Intracellular Imaging and Targeted Cancer Therapy

2021 ◽  
Author(s):  
Yong-Xiang Wu ◽  
Dailiang Zhang ◽  
Xiaoxiao Hu ◽  
Ruizi Peng ◽  
Junbin Li ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Targeted Cancer Therapy ◽  
Intracellular Imaging ◽  
Two Photon

scholarly journals Immune Cell Membrane‐Coated Biomimetic Nanoparticles for Targeted Cancer Therapy

Small ◽  
2021 ◽  
pp. 2006484
Author(s):  
Fatemeh Oroojalian ◽  
Mohammad Beygi ◽  
Behzad Baradaran ◽  
Ahad Mokhtarzadeh ◽  
Mohammad‐Ali Shahbazi
Keyword(s):  
Cancer Therapy ◽  
Cell Membrane ◽  
Immune Cell ◽  
Targeted Cancer Therapy ◽  
Biomimetic Nanoparticles
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