A cost-effective disposable graphene-modified electrode decorated with alternating layers of Au NPs for the simultaneous detection of dopamine and uric acid in human urine

RSC Advances ◽  
2016 ◽  
Vol 6 (84) ◽  
pp. 80756-80765 ◽  
Author(s):  
Nadeem Baig ◽  
Abdel-Nasser Kawde

A disposable electrode based on a highly sensitive and readily fabricated arrangement of alternating AuNP and graphene layers was introduced for the simultaneous determination of dopamine and uric acid.

2008 ◽  
Vol 24 (12) ◽  
pp. 1589-1592 ◽  
Author(s):  
Yuegang ZUO ◽  
Chengjun WANG ◽  
Jiping ZHOU ◽  
Amita SACHDEVA ◽  
Vanessa C. RUELOS

Materials ◽  
2018 ◽  
Vol 11 (9) ◽  
pp. 1691 ◽  
Author(s):  
Yue Wang ◽  
Tian Yang ◽  
Yasushi Hasebe ◽  
Zhiqiang Zhang ◽  
Dongping Tao

Carbon black (CB) and carbon nanotube (CNT) co-doped polyimide (PI) modified glassy carbon electrode (CB-CNT/PI/GCE) was first prepared for the simultaneous determination of ascorbic acid (AA), dopamine (DA), and uric acid (UA). The CB-CNT/PI/GCE exhibited persistent electrochemical behavior and excellent catalytic activities. Cyclic voltammetry (CV) and differential pulse voltammetry (DPV) were used for the simultaneous detection of AA, DA, and UA in their ternary mixture. The peak separations between AA and DA, and DA and UA, are up to 166 mV and 148 mV, respectively. The CB-CNT/PI/GCE exhibited high sensitivity to DA and UA, with the detection limit of 1.9 µM and 3 µM, respectively. In addition, the CB-CNT/PI/GCE showed sufficient selectivity and long-term stability, and was applicable to detect AA, DA, and UA in human urine sample.


Biosensors ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 287
Author(s):  
Maria A. Bukharinova ◽  
Natalia Yu. Stozhko ◽  
Elizaveta A. Novakovskaya ◽  
Ekaterina I. Khamzina ◽  
Aleksey V. Tarasov ◽  
...  

The paper describes the development of a carbon veil-based electrode (CVE) for determining uric acid (UA) in saliva. The electrode was manufactured by lamination technology, electrochemically activated and used as a highly sensitive voltammetric sensor (CVEact). Potentiostatic polarization of the electrode at 2.0 V in H2SO4 solution resulted in a higher number of oxygen and nitrogen-containing groups on the electrode surface; lower charge transfer resistance; a 1.5 times increase in the effective surface area and a decrease in the UA oxidation potential by over 0.4 V, compared with the non-activated CVE, which was confirmed by energy dispersive X-ray spectroscopy, electrochemical impedance spectroscopy, chronoamperometry and linear sweep voltammetry. The developed sensor is characterized by a low detection limit of 0.05 µM and a wide linear range (0.09–700 µM). The results suggest that the sensor has perspective applications for quick determination of UA in artificial and human saliva. RSD does not exceed 3.9%, and recovery is 96–105%. UA makes a significant contribution to the antioxidant activity (AOA) of saliva (≈60%). In addition to its high analytical characteristics, the important advantages of the proposed CVEact are the simple, scalable, and cost-effective manufacturing technology and the absence of additional complex and time-consuming modification operations.


2018 ◽  
Vol 165 (5) ◽  
pp. B174-B183 ◽  
Author(s):  
A. J. Saleh Ahammad ◽  
Tamanna Islam ◽  
Md. Mahedi Hasan ◽  
M. N. Islam Mozumder ◽  
Rejwana Karim ◽  
...  

Author(s):  
Qinyi Fu ◽  
Hongwei Zheng ◽  
Xiangning Han ◽  
Limin Cao ◽  
Jianxin Sui

AbstractA highly sensitive high-performance liquid chromatography (HPLC) method was developed for the simultaneous determination of eight biogenic amines in aquatic products. The biogenic amines in the sample were extracted with 5% trichloroacetic acid, derived with dansyl chloride (Dns-Cl) and quantified by a UV detector. The results showed that tryptamine (TRY), 2-phenethylamine (PHE), putrescine (PUT), cadaverine (CAD), histamine (HIS), tyramine (TPY), spermidine (SPD), and spermine (SPM) were effectively separated in 18 min in the range of 0.1–50 mg/kg with a good linear coefficient (r2 > 0.999). The detection limits (LODs) of the eight biogenic amines were 0.007–0.021 mg/kg while the limits of quantification (LOQs) were 0.024–0.069 mg/kg with the recoveries basically between 68 and 123%. The determination of eight biogenic amines in five commercial fermented aquatic products indicating that the developed method could be applied for the simultaneous detection of biogenic amines in multiple aquatic products.


The Analyst ◽  
2018 ◽  
Vol 143 (18) ◽  
pp. 4422-4428 ◽  
Author(s):  
Jin Huang ◽  
Xue-Li Zhu ◽  
Yu-Min Wang ◽  
Jian-Hui Ge ◽  
Jin-Wen Liu ◽  
...  

In this work, a versatile point-of-care assay platform based on a microfluidic paper-based analytic device (μPAD) was developed for the simultaneous detection of multiple targets.


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