RTG-loaded nanomicelles (CS–VES–NAC) for oral anti-HIV drug delivery

RSC Advances ◽  
2016 ◽  
Vol 6 (79) ◽  
pp. 75890-75895 ◽  
Author(s):  
Liming Hu ◽  
Jiazhou Wu ◽  
Zhipeng Li ◽  
Ming Bu ◽  
Shenglin Qiao ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Vitamin E ◽  
Vitamin E Succinate ◽  
Self Assembled ◽  
Anti Hiv

An acetylcysteine–chitosan–vitamin E succinate copolymer (CVN) was synthesized from chitosan (CS), vitamin E succinate (VES) and N-acetyl-l-cysteine (NAC) as self-assembled nanomicelles for multifunctional delivery of anti-HIV drug Raltegravir (RTG).

Vitamin E–TPGS Stabilized Self-Assembled Tripeptide Nanostructures for Drug Delivery

2015 ◽  
Vol 15 (13) ◽  
pp. 1227-1235 ◽  
Author(s):  
Santosh Yadav ◽  
Vartika Rai ◽  
Manohar Mahato ◽  
Mahak Singh ◽  
Smriti Deka ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Vitamin E ◽  
Vitamin E Tpgs ◽  
Self Assembled

scholarly journals Efficient drug delivery and anticancer effect of micelles based on vitamin E succinate and chitosan derivatives

2021 ◽  
Vol 6 (10) ◽  
pp. 3025-3035
Author(s):  
Xiaotong Chen ◽  
Junxiang Gu ◽  
Le Sun ◽  
Wenya Li ◽  
Lili Guo ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Vitamin E ◽  
Vitamin E Succinate ◽  
Anticancer Effect ◽  
Chitosan Derivatives

scholarly journals A Co-Delivery Strategy of Abemaciclib Combined with Vitamin E Succinate Based on Hyaluronic Acid Modified Calcium Phosphate to Enhance the Anti-Cancer Effect

2021 ◽  
Author(s):  
Yuanyuan Liu ◽  
Na Gan ◽  
Shuangshuang Zhang ◽  
Qiaomei Sun ◽  
Xin Wei ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Vitamin E ◽  
Calcium Phosphate ◽  
Synergistic Effects ◽  
Hollow Structure ◽  
Inhibitory Effect ◽  
Vitamin E Succinate ◽  
Delivery Strategy ◽  
Anti Cancer ◽  
High Doses

Abstract Combination therapy including anticancer drugs usually induces synergistic effects, especially in combination with natural compounds as a chemical sensitizer. Nano-based drug delivery technology is also effective in solving the toxicity of single drugs at high doses. In this study, we established a co-delivery strategy for abemaciclib (ABE) combined with vitamin E succinate (VES) based on HA-modified calcium phosphate (CaP) nanomaterials to enhance anti-cancer effect. The nano-sized HA/CaP particles (90 nm) have a hollow structure. Surprisingly, after modification with HA, HA/CaP has more pH sensitivity. CaP released 30% ABE and 91% VES at pH 7.4, whereas HA/CaP vsreleased 14% ABE and 32% VES at the same pH. Cell experiments showed that HA/CaP/ABE-VES had stronger cell inhibitory effect on MCF-7 compared with CaP/ABE-VES. This inorganic/organic composite for the co-delivery of ABE and VES has obvious tumor inhibition effect, and is ideal for anti-tumor drug delivery.

Self-Assembled Nanocarriers Based on Amphiphilic Natural Polymers for Anti- Cancer Drug Delivery Applications

2018 ◽  
Vol 23 (35) ◽  
Author(s):  
Sally Sabra ◽  
Mona Abdelmoneem ◽  
Mahmoud Abdelwakil ◽  
Moustafa Taha Mabrouk ◽  
Doaa Anwar ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Drug ◽  
Natural Polymers ◽  
Anti Cancer ◽  
Drug Delivery Applications ◽  
Self Assembled ◽  
Cancer Drug Delivery

128 POSTER Vitamin E succinate inhibits the in vitro growth of pancreatic cancer cells

2006 ◽  
Vol 4 (12) ◽  
pp. 42
Author(s):  
D. Kumar ◽  
D. Patacsil ◽  
S. Osayi ◽  
P.C. Gokhale ◽  
M. Verma ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Vitamin E ◽  
Cancer Cells ◽  
In Vitro Growth ◽  
Vitamin E Succinate ◽  
Pancreatic Cancer Cells

Vitamin E Succinate Promotes Breast Cancer Tumor Dormancy

2000 ◽  
Vol 93 (1) ◽  
pp. 163-170 ◽  
Author(s):  
Mokenge P. Malafa ◽  
Leslie T. Neitzel
Keyword(s):  
Breast Cancer ◽  
Vitamin E ◽  
Tumor Dormancy ◽  
Vitamin E Succinate ◽  
Cancer Tumor
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