Vitamin E Succinate Promotes Breast Cancer Tumor Dormancy

2000 ◽  
Vol 93 (1) ◽  
pp. 163-170 ◽  
Author(s):  
Mokenge P. Malafa ◽  
Leslie T. Neitzel
Keyword(s):  
Breast Cancer ◽  
Vitamin E ◽  
Tumor Dormancy ◽  
Vitamin E Succinate ◽  
Cancer Tumor

scholarly journals Anti-Cancer Effects of Sulfasalazine and Vitamin E Succinate in MDA-MB 231 Triple-Negative Breast Cancer Cells

2019 ◽  
Vol 16 (4) ◽  
pp. 494-500 ◽  
Author(s):  
Chyou-Wei Wei ◽  
Yung-Luen Yu ◽  
Ji-Ying Lu ◽  
Yu-Ting Hung ◽  
Hsiao-Chun Liu ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Vitamin E ◽  
Cancer Cells ◽  
Triple Negative Breast Cancer ◽  
Breast Cancer Cells ◽  
Triple Negative ◽  
Vitamin E Succinate ◽  
Anti Cancer

scholarly journals A Peptide Conjugate of Vitamin E Succinate Targets Breast Cancer Cells with High ErbB2 Expression

2007 ◽  
Vol 67 (7) ◽  
pp. 3337-3344 ◽  
Author(s):  
Xiu-Fang Wang ◽  
Marc Birringer ◽  
Lan-Feng Dong ◽  
Pavel Veprek ◽  
Pauline Low ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Vitamin E ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Vitamin E Succinate ◽  
Erbb2 Expression

Vitamin E Succinate Decreases Lung Cancer Tumor Growth in Mice

2005 ◽  
Vol 127 (2) ◽  
pp. 139-143 ◽  
Author(s):  
Jacquelyn Quin ◽  
Deborah Engle ◽  
Abigail Litwiller ◽  
Elizabeth Peralta ◽  
Anthony Grasch ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Vitamin E ◽  
Tumor Growth ◽  
Vitamin E Succinate ◽  
Cancer Tumor

Vitamin E succinate decreases lung cancer tumor growth in mice

2004 ◽  
Vol 121 (2) ◽  
pp. 281
Author(s):  
J. Quin ◽  
D. Engles ◽  
A. Litwiller ◽  
E. Peralta ◽  
A. Grasch ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Vitamin E ◽  
Tumor Growth ◽  
Vitamin E Succinate ◽  
Cancer Tumor

scholarly journals Fat Composition Measured by Proton Spectroscopy: A Breast Cancer Tumor Marker?

Diagnostics ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 564
Author(s):  
Almir Bitencourt ◽  
Varadan Sevilimedu ◽  
Elizabeth A. Morris ◽  
Katja Pinker ◽  
Sunitha B. Thakur
Keyword(s):  
Breast Cancer ◽  
Saturation Index ◽  
Multivariable Analysis ◽  
Area Under The Curve ◽  
Resonance Spectroscopy ◽  
Breast Cancers ◽  
Her2 Positive ◽  
Tumor Tissues ◽  
Cancer Tumor ◽  
Fat Composition

Altered metabolism including lipids is an emerging hallmark of breast cancer. The purpose of this study was to investigate if breast cancers exhibit different magnetic resonance spectroscopy (MRS)-based lipid composition than normal fibroglandular tissue (FGT). MRS spectra, using the stimulated echo acquisition mode sequence, were collected with a 3T scanner from patients with suspicious lesions and contralateral normal tissue. Fat peaks at 1.3 + 1.6 ppm (L13 + L16), 2.1 + 2.3 ppm (L21 + L23), 2.8 ppm (L28), 4.1 + 4.3 ppm (L41 + L43), and 5.2 + 5.3 ppm (L52 + L53) were quantified using LCModel software. The saturation index (SI), number of double bods (NBD), mono and polyunsaturated fatty acids (MUFA and PUFA), and mean chain length (MCL) were also computed. Results showed that mean concentrations of all lipid metabolites and PUFA were significantly lower in tumors compared with that of normal FGT (p ≤ 0.002 and 0.04, respectively). The measure best separating normal and tumor tissues after adjusting with multivariable analysis was L21 + L23, which yielded an area under the curve of 0.87 (95% CI: 0.75–0.98). Similar results were obtained between HER2 positive versus HER2 negative tumors. Hence, MRS-based lipid measurements may serve as independent variables in a multivariate approach to increase the specificity of breast cancer characterization.

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