Template-based formation of ultrasound microbubble contrast agents

RSC Advances ◽  
2016 ◽  
Vol 6 (73) ◽  
pp. 69185-69190 ◽  
Author(s):  
Hsiu-Ying Huang ◽  
Cheng-An J. Lin ◽  
Walter H. Chang ◽  
Chih-Kuang Yeh

Precisely controlling microbubble size is critical for medical ultrasound imaging, where large microbubble contrast agents may lead to pulmonary microvascular embolization. Here we introduced a method of preparing uniform microbubbles for ultrasound images.

2003 ◽  
Vol 3 (1) ◽  
pp. 11-17 ◽  
Author(s):  
Alan Cuthbertson ◽  
Audun Tornes ◽  
Magne Solbakken ◽  
Ove Moen ◽  
Morten Eriksen

2004 ◽  
Author(s):  
Kausik Sarkar ◽  
Pankaj Jain ◽  
Dhiman Chatterjee

Microbubble based contrast agents improves medical ultrasound images. Destruction of contrast agent Definity® (Bristol Meyer-Squibb Imaging, North Ballerina, MA) is studied using broadband attenuation technique. Single-cycle ultrasound pulses are sent through a bubble suspension at different pulse repetition frequencies (PRF) and pressure amplitudes. For each PRF, there is a critical pressure amplitude (~1.1–1.2MPa for 50, 100, 200 Hz PRFs studied), below which there is no evidence of bubble destruction. Above the critical pressure amplitudes the rate of destruction depends on PRF and pressure. But at high pressure amplitudes (e.g. 2.97 MPa) destruction becomes independent at higher PRFs.


1995 ◽  
pp. 349-355
Author(s):  
Timothy J. Pitt ◽  
Leonard A. Ferrari ◽  
Andy Healey ◽  
R. Anthony Reynolds ◽  
Keith N. Humphries

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